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Volumn 14, Issue 12, 2013, Pages 1152-1154

Axitinib dose titration: What's the limiting factor?

Author keywords

[No Author keywords available]

Indexed keywords

AXITINIB; PLACEBO; SORAFENIB;

EID: 84886730266     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(13)70489-3     Document Type: Letter
Times cited : (5)

References (10)
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    • Van der Veldt AA, Eechoute K, Gelderblom H, et al. Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib. Clin Cancer Res 2011, 17:620-629.
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    • Van der Veldt, A.A.1    Eechoute, K.2    Gelderblom, H.3
  • 2
    • 84880157519 scopus 로고    scopus 로고
    • Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis
    • Rini BI, Garrett M, Poland B, et al. Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis. J Clin Pharmacol 2013, 53:491-504.
    • (2013) J Clin Pharmacol , vol.53 , pp. 491-504
    • Rini, B.I.1    Garrett, M.2    Poland, B.3
  • 3
    • 84864997618 scopus 로고    scopus 로고
    • A phase II trial of intrapatient dose-escalated sorafenib in patients with metastatic renal cell carcinoma
    • Amato R, Zhai J, Willis J, Saxena S, De Foe M A phase II trial of intrapatient dose-escalated sorafenib in patients with metastatic renal cell carcinoma. Clin Genitourin Cancer 2012, 10:153-158.
    • (2012) Clin Genitourin Cancer , vol.10 , pp. 153-158
    • Amato, R.1    Zhai, J.2    Willis, J.3    Saxena, S.4    De Foe, M.5
  • 4
    • 62449186539 scopus 로고    scopus 로고
    • Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinoma
    • Escudier B, Szczylik C, Hutson TE, et al. Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinoma. J Clin Oncol 2009, 27:1280-1289.
    • (2009) J Clin Oncol , vol.27 , pp. 1280-1289
    • Escudier, B.1    Szczylik, C.2    Hutson, T.E.3
  • 5
    • 82755173186 scopus 로고    scopus 로고
    • Efficacy and safety of intrapatient dose escalation of sorafenib as first-line treatment for metastatic renal cell carcinoma (mRCC)
    • abstr 4609.
    • Gore ME, Jones RJ, Ravaud A, et al. Efficacy and safety of intrapatient dose escalation of sorafenib as first-line treatment for metastatic renal cell carcinoma (mRCC). Proc Am Soc Clin Oncol 2011, 29(suppl). abstr 4609.
    • (2011) Proc Am Soc Clin Oncol , vol.29 , Issue.SUPPL.
    • Gore, M.E.1    Jones, R.J.2    Ravaud, A.3
  • 6
    • 84860355062 scopus 로고    scopus 로고
    • Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma
    • Motzer RJ, Hutson TE, Olsen MR, et al. Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma. J Clin Oncol 2012, 30:1371-1377.
    • (2012) J Clin Oncol , vol.30 , pp. 1371-1377
    • Motzer, R.J.1    Hutson, T.E.2    Olsen, M.R.3
  • 7
    • 84874082452 scopus 로고    scopus 로고
    • A new modified schedule of sunitinib for metastatic renal cell carcinoma: a retrospective analysis
    • Buti S, Donini M, Lazzarelli S, Passalacqua R A new modified schedule of sunitinib for metastatic renal cell carcinoma: a retrospective analysis. Acta Biomed 2012, 83:88-94.
    • (2012) Acta Biomed , vol.83 , pp. 88-94
    • Buti, S.1    Donini, M.2    Lazzarelli, S.3    Passalacqua, R.4
  • 8
    • 84893831040 scopus 로고    scopus 로고
    • Clinical outcomes in metastatic renal cell carcinoma patients treated with alternative sunitinib schedules
    • published online Sept 6.
    • Atkinson BJ, Kalra S, Wang X, et al. Clinical outcomes in metastatic renal cell carcinoma patients treated with alternative sunitinib schedules. J Urol 2013, published online Sept 6. 10.1016/j.juro.2013.08.090.
    • (2013) J Urol
    • Atkinson, B.J.1    Kalra, S.2    Wang, X.3
  • 9
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    • Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial
    • published online Oct 18.
    • Rini BI, Melichar B, Ueda T, et al. Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial. Lancet Oncol 2013, published online Oct 18. http://dx.doi.org/10.1016/S1470-2045(13)70464-9.
    • (2013) Lancet Oncol
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  • 10
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    • Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial
    • in press.
    • Hutson TE, Gallardo J, Lesovoy V, et al. Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial. Lancet Oncol 2013, in press.
    • (2013) Lancet Oncol
    • Hutson, T.E.1    Gallardo, J.2    Lesovoy, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.