-
2
-
-
77950329947
-
Evidence for polygenic susceptibility to multiple sclerosis-The shape of things to come
-
Bush WS, Sawcer SJ, de Jager PL, Oksenberg JR, McCauley JL, Pericak-Vance MA et al. Evidence for polygenic susceptibility to multiple sclerosis-the shape of things to come. Am J Hum Genet 2010; 86: 621-625.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 621-625
-
-
Bush, W.S.1
Sawcer, S.J.2
De Jager, P.L.3
Oksenberg, J.R.4
McCauley, J.L.5
Pericak-Vance, M.A.6
-
4
-
-
80051684615
-
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
-
Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476: 214-219.
-
(2011)
Nature
, vol.476
, pp. 214-219
-
-
Sawcer, S.1
Hellenthal, G.2
Pirinen, M.3
Spencer, C.C.4
Patsopoulos, N.A.5
Moutsianas, L.6
-
5
-
-
35748981184
-
Association scan of 14, 500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A et al. Association scan of 14, 500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007; 39: 1329-1337.
-
(2007)
Nat Genet
, vol.39
, pp. 1329-1337
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
-
6
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007; 357: 851-862.
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
-
7
-
-
55849139823
-
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500, 000 single nucleotide polymorphisms
-
Comabella M, Craig DW, Camina-Tato M, Morcillo C, Lopez C, Navarro A et al. Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500, 000 single nucleotide polymorphisms. PLoS One 2008; 3: E3490.
-
(2008)
PLoS One
, vol.3
-
-
Comabella, M.1
Craig, D.W.2
Camina-Tato, M.3
Morcillo, C.4
Lopez, C.5
Navarro, A.6
-
8
-
-
67649881102
-
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
-
ANZGENE-consortium
-
ANZGENE-consortium. Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet 2009; 41: 824-828.
-
(2009)
Nat Genet
, vol.41
, pp. 824-828
-
-
-
9
-
-
58949099391
-
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
-
Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F et al. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet 2009; 18: 767-778.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 767-778
-
-
Baranzini, S.E.1
Wang, J.2
Gibson, R.A.3
Galwey, N.4
Naegelin, Y.5
Barkhof, F.6
-
10
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 2009; 41: 776-782.
-
(2009)
Nat Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
De Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
-
11
-
-
76049083598
-
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene
-
Jakkula E, Leppa V, Sulonen AM, Varilo T, Kallio S, Kemppinen A et al. Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet 2010; 86: 285-291.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 285-291
-
-
Jakkula, E.1
Leppa, V.2
Sulonen, A.M.3
Varilo, T.4
Kallio, S.5
Kemppinen, A.6
-
12
-
-
77956649792
-
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis
-
Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Muller-Sarnowski F et al. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. J Neuroimmunol 2010; 227: 162-166.
-
(2010)
J Neuroimmunol
, vol.227
, pp. 162-166
-
-
Nischwitz, S.1
Cepok, S.2
Kroner, A.3
Wolf, C.4
Knop, M.5
Muller-Sarnowski, F.6
-
13
-
-
77952884985
-
Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis
-
Sanna S, Pitzalis M, Zoledziewska M, Zara I, Sidore C, Murru R et al. Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet 2010; 42: 495-497.
-
(2010)
Nat Genet
, vol.42
, pp. 495-497
-
-
Sanna, S.1
Pitzalis, M.2
Zoledziewska, M.3
Zara, I.4
Sidore, C.5
Murru, R.6
-
14
-
-
65549084289
-
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
-
Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D et al. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet 2009; 18: 2078-2090.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2078-2090
-
-
Baranzini, S.E.1
Galwey, N.W.2
Wang, J.3
Khankhanian, P.4
Lindberg, R.5
Pelletier, D.6
-
15
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet 2011; 7: E1002254.
-
(2011)
PLoS Genet
, vol.7
-
-
Cotsapas, C.1
Voight, B.F.2
Rossin, E.3
Lage, K.4
Neale, B.M.5
Wallace, C.6
-
16
-
-
73249122274
-
Mapping of multiple susceptibility variants within the MHC region for 7 immunemediated diseases
-
Rioux JD, Goyette P, Vyse TJ, Hammarstrom L, Fernando MM, Green T et al. Mapping of multiple susceptibility variants within the MHC region for 7 immunemediated diseases. Proc Natl Acad Sci USA 2009; 106: 18680-18685.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18680-18685
-
-
Rioux, J.D.1
Goyette, P.2
Vyse, T.J.3
Hammarstrom, L.4
Fernando, M.M.5
Green, T.6
-
17
-
-
79952158486
-
Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility
-
Couturier N, Bucciarelli F, Nurtdinov RN, Debouverie M, Lebrun-Frenay C, Defer G et al. Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility. Brain 2011; 134(Pt 3): 693-703.
-
(2011)
Brain
, vol.134
, Issue.PART 3
, pp. 693-703
-
-
Couturier, N.1
Bucciarelli, F.2
Nurtdinov, R.N.3
Debouverie, M.4
Lebrun-Frenay, C.5
Defer, G.6
-
18
-
-
65249155425
-
The role of the CD58 locus in multiple sclerosis
-
De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L et al. The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci USA 2009; 106: 5264-5269.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5264-5269
-
-
De Jager, P.L.1
Baecher-Allan, C.2
Maier, L.M.3
Arthur, A.T.4
Ottoboni, L.5
Barcellos, L.6
-
19
-
-
84865261493
-
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis
-
Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F et al. TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. Nature 2012; 488: 508-511.
-
(2012)
Nature
, vol.488
, pp. 508-511
-
-
Gregory, A.P.1
Dendrou, C.A.2
Attfield, K.E.3
Haghikia, A.4
Xifara, D.K.5
Butter, F.6
-
20
-
-
34548351247
-
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
-
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 2007; 39: 1083-1091.
-
(2007)
Nat Genet
, vol.39
, pp. 1083-1091
-
-
Gregory, S.G.1
Schmidt, S.2
Seth, P.3
Oksenberg, J.R.4
Hart, J.5
Prokop, A.6
-
21
-
-
58949100205
-
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production
-
Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C et al. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet 2009; 5: E1000322.
-
(2009)
PLoS Genet
, vol.5
-
-
Maier, L.M.1
Lowe, C.E.2
Cooper, J.3
Downes, K.4
Anderson, D.E.5
Severson, C.6
-
22
-
-
71849098862
-
Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score
-
De Jager PL, Chibnik LB, Cui J, Reischl J, Lehr S, Simon KC et al. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score. Lancet Neurol 2009; 8: 1111-1119.
-
(2009)
Lancet Neurol
, vol.8
, pp. 1111-1119
-
-
De Jager, P.L.1
Chibnik, L.B.2
Cui, J.3
Reischl, J.4
Lehr, S.5
Simon, K.C.6
-
23
-
-
79551484517
-
Aggregation of multiple sclerosis genetic risk variants in multiple and single case families
-
Gourraud PA, McElroy JP, Caillier SJ, Johnson BA, Santaniello A, Hauser SL et al. Aggregation of multiple sclerosis genetic risk variants in multiple and single case families. Ann Neurol 2011; 69: 65-74.
-
(2011)
Ann Neurol
, vol.69
, pp. 65-74
-
-
Gourraud, P.A.1
McElroy, J.P.2
Caillier, S.J.3
Johnson, B.A.4
Santaniello, A.5
Hauser, S.L.6
-
24
-
-
77649289047
-
What role for genetics in the prediction of multiple sclerosis?
-
Sawcer S, Ban M, Wason J, Dudbridge F. What role for genetics in the prediction of multiple sclerosis? Ann Neurol 2010; 67: 3-10.
-
(2010)
Ann Neurol
, vol.67
, pp. 3-10
-
-
Sawcer, S.1
Ban, M.2
Wason, J.3
Dudbridge, F.4
-
25
-
-
84255194782
-
Genomewide meta-analysis identifies novel multiple sclerosis susceptibility loci
-
Patsopoulos NA, Esposito F, Reischl J, Lehr S, Bauer D, Heubach J et al. Genomewide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol 2011; 70: 897-912.
-
(2011)
Ann Neurol
, vol.70
, pp. 897-912
-
-
Patsopoulos, N.A.1
Esposito, F.2
Reischl, J.3
Lehr, S.4
Bauer, D.5
Heubach, J.6
-
26
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467: 832-838.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
Berndt, S.I.4
Weedon, M.N.5
Rivadeneira, F.6
-
27
-
-
0036151386
-
Genetic basis for clinical expression in multiple sclerosis
-
Barcellos LF, Oksenberg JR, Green AJ, Bucher P, Rimmler JB, Schmidt S et al. Genetic basis for clinical expression in multiple sclerosis. Brain 2002; 125(Pt 1): 150-158.
-
(2002)
Brain
, vol.125
, Issue.PART 1
, pp. 150-158
-
-
Barcellos, L.F.1
Oksenberg, J.R.2
Green, A.J.3
Bucher, P.4
Rimmler, J.B.5
Schmidt, S.6
-
28
-
-
0026354602
-
Diagnostic criteria for multiple sclerosis research involving multiply affected families
-
Goodkin DE, Doolittle TH, Hauser SS, Ransohoff RM, Roses AD, Rudick RA. Diagnostic criteria for multiple sclerosis research involving multiply affected families. Arch Neurol 1991; 48: 805-807.
-
(1991)
Arch Neurol
, vol.48
, pp. 805-807
-
-
Goodkin, D.E.1
Doolittle, T.H.2
Hauser, S.S.3
Ransohoff, R.M.4
Roses, A.D.5
Rudick, R.A.6
-
29
-
-
57249114505
-
SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
-
Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, de Bakker PI. SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008; 24: 2938-2939.
-
(2008)
Bioinformatics
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.L.3
Nizzari, M.M.4
O'Donnell, C.J.5
De Bakker, P.I.6
|