A better prognosis for Merkel cell carcinoma of unknown primary origin

American Journal of Surgery

Volumn 206, Issue 5, 2013, Pages 752-757

  Chen, Kathryn T ^a   Papavasiliou, Pavlos ^a   Edwards, Kyle ^b   Zhu, Fang ^a   Perlis, Clifford ^a   Wu, Hong ^a   Turaka, Aruna ^a   Berger, Adam ^b   Farma, Jeffrey M ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

Merkel cell carcinoma; Nodal metastasis; Survival; Unknown primary

Indexed keywords

ADULT; AGED; ARTICLE; CANCER OF UNKNOWN PRIMARY SITE; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE DISSECTION; MALE; MERKEL CELL TUMOR; OVERALL SURVIVAL; PRIORITY JOURNAL;

MERKEL CELL CARCINOMA; NODAL METASTASIS; SURVIVAL; UNKNOWN PRIMARY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, MERKEL CELL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASMS, UNKNOWN PRIMARY; PROGNOSIS; SKIN NEOPLASMS;

EID: 84886726126     PISSN: 00029610     EISSN: 18791883     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2013.02.005     Document Type: Article

References (44)

1. D. Lyhne, J. Lock-Andersen, and K. Dahlstrom Rising incidence of Merkel cell carcinoma J Plast Surg Hand Surgery 45 2011 274 280
2. B. Lemos, and P. Nghiem Merkel cell carcinoma: more deaths but still no pathway to blame J Invest Dermatol 127 2007 2100 2103
3. N.C. Hodgson Merkel cell carcinoma: changing incidence trends J Surg Oncol 89 2005 1 4
4. M. Agelli, and L.X. Clegg Epidemiology of primary Merkel cell carcinoma in the United States J Am Acad Dermatol 49 2003 832 841
5. L.G. Feun, N. Savaraj, and S.S. Legha Chemotherapy for metastatic Merkel cell carcinoma. Review of the M.D. Anderson Hospital's experience Cancer 62 1988 683 685
6. B. Llombart, C. Monteagudo, and J.A. Lopez-Guerrero Clinicopathological and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers Histopathology 46 2005 622 634
7. H. Majewska, and W. Biernat Merkel cell carcinoma. Pathological and molecular aspects of diagnosis and clinical features Pol J Pathol 61 2010 117 123
8. J. Albores-Saavedra, K. Batich, and F. Chable-Montero Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study J Cutan Pathol 37 2010 20 27
9. R.K. Sibley, L.P. Dehner, and J. Rosai Primary neuroendocrine (Merkel cell?) carcinoma of the skin. I. A clinicopathologic and ultrastructural study of 43 cases Am J Surg Pathol 9 1985 95 108
10. T.F. Warner, H. Uno, and G.R. Hafez Merkel cells and Merkel cell tumors. Ultrastructure, immunocytochemistry and review of the literature Cancer 52 1983 238 245
11. A.J. Hanly, G.W. Elgart, and M. Jorda Analysis of thyroid transcription factor-1 and cytokeratin 20 separates merkel cell carcinoma from small cell carcinoma of lung J Cutan Pathol 27 2000 118 120
12. V. Koljonen Merkel cell carcinoma World J Surg Oncol 4 2006 7
13. S. Kuwamoto Recent advances in the biology of Merkel cell carcinoma Hum Pathol 42 2011 1063 1077
14. K.A. Metz, M. Jacob, and U. Schmidt Merkel cell carcinoma of the eyelid: histological and immunohistochemical features with special respect to differential diagnosis Graefes Arch Clin Exp Ophthalmol 236 1998 561 566
15. M. Poulsen Merkel-cell carcinoma of the skin Lancet Oncol 5 2004 593 599
16. U. Schmidt, U. Muller, and K.A. Metz Cytokeratin and neurofilament protein staining in Merkel cell carcinoma of the small cell type and small cell carcinoma of the lung Am J Dermatopathol 20 1998 346 351
17. B.D. Lemos, B.E. Storer, and J.G. Iyer Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system J Am Acad Dermatol 63 2010 751 761
18. S. Akhtar, K.K. Oza, and J. Wright Merkel cell carcinoma: report of 10 cases and review of the literature J Am Acad Dermatol 43 2000 755 767
19. M.J. Veness, L. Perera, and J. McCourt Merkel cell carcinoma: improved outcome with adjuvant radiotherapy ANZ J Surg 75 2005 275 281
20. M. Foote, M. Veness, and D. Zarate Merkel cell carcinoma: the prognostic implications of an occult primary in stage IIIB (nodal) disease J Am Acad Dermatol 67 2012 395 399
21. R.C. Fields, K.J. Busam, and J.F. Chou Five hundred patients with Merkel cell carcinoma evaluated at a single institution Ann Surgery 254 2011 465 473 discussion 473-5
22. Merkel Cell Carcinoma ed 7 2009 Springer-Verlag New York, NY
23. J.D. Hainsworth, E.P. Wright, and D.H. Johnson Poorly differentiated carcinoma of unknown primary site: clinical usefulness of immunoperoxidase staining J Clin Oncol 9 1991 1931 1938
24. D.R. Spigel, J.D. Hainsworth, and F.A. Greco Neuroendocrine carcinoma of unknown primary site Semin Oncol 36 2009 52 59
25. E.M. Copeland, and C.M. McBride Axillary metastases from unknown primary sites Ann Surg 178 1973 25 27
26. K.G. Lewis, M.A. Weinstock, and A.L. Weaver Adjuvant local irradiation for Merkel cell carcinoma Arch Dermatol 142 2006 693 700
27. J.N. Cormier, Y. Xing, and L. Feng Metastatic melanoma to lymph nodes in patients with unknown primary sites Cancer 106 2006 2012 2020
28. C.C. Lee, M.B. Faries, and L.A. Wanek Improved survival after lymphadenectomy for nodal metastasis from an unknown primary melanoma J Clin Oncol 26 2008 535 541
29. S.P. Prens, A.P. van der Ploeg, and A.C. van Akkooi Outcome after therapeutic lymph node dissection in patients with unknown primary melanoma site Ann Surg Oncol 18 2011 3586 3592
30. V.J. McGovern Spontaneous regression of melanoma Pathology 7 1975 91 99
31. D. Bottger, R.V. Dowden, and P.P. Kay Complete spontaneous regression of cutaneous primary malignant melanoma Plast Reconstr Surg 89 1992 548 553
32. T.S. Wang, L. Lowe, and J.W. Smith 2nd Complete spontaneous regression of pulmonary metastatic melanoma Dermatol Surg 24 1998 915 919
33. A.S. Sroujieh Spontaneous regression of intestinal malignant melanoma from an occult primary site Cancer 62 1988 1247 1250
34. S.W. McCarthy, A.A. Palmer, and P.M. Bale Naevus cells in lymph nodes Pathology 6 1974 351 358
35. T. Dasgupta, L. Bowden, and J.W. Berg Malignant melanoma of unknown primary origin Surg Gynecol Obstet 117 1963 341 345
36. A.G. Richetta, M. Mancini, and A. Torroni Total spontaneous regression of advanced merkel cell carcinoma after biopsy: review and a new case Dermatol Surg 34 2008 815 822
37. H. Takenaka, S. Kishimoto, and R. Shibagaki Merkel cell carcinoma with partial spontaneous regression: an immunohistochemical, ultrastructural, and TUNEL labeling study Am J Dermatopathol 19 1997 614 618
38. T.J. Brown, B.A. Jackson, and D.F. Macfarlane Merkel cell carcinoma: spontaneous resolution and management of metastatic disease Dermatol Surg 25 1999 23 25
39. L. Junquera, A. Torre, and J.C. Vicente Complete spontaneous regression of Merkel cell carcinoma Ann Otol Rhinol Laryngol 114 2005 376 380
40. M.J. Vesely, D.J. Murray, and P.C. Neligan Complete spontaneous regression in Merkel cell carcinoma J Plast Reconstr Aesthet Surgery 61 2008 165 171
41. T. Inoue, K. Yoneda, and M. Manabe Spontaneous regression of merkel cell carcinoma: a comparative study of TUNEL index and tumor-infiltrating lymphocytes between spontaneous regression and non-regression group J Dermatol Sci 24 2000 203 211
42. H. Feng, M. Shuda, and Y. Chang Clonal integration of a polyomavirus in human Merkel cell carcinoma Science 319 2008 1096 1100
43. K.G. Paulson, J.J. Carter, and L.G. Johnson Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients Cancer Res 70 2010 8388 8397
44. J.L. Deneve, J.L. Messina, and S.S. Marzban Merkel cell carcinoma of unknown primary origin Ann Surg Oncol 19 2012 2360 2366