Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model

Journal of Surgical Research

Volumn 185, Issue 1, 2013, Pages 455-462

  Kurobe, Hirotsugu ^a   Hirata, Yoichiro ^a,b   Matsuoka, Yuki ^a   Sugasawa, Noriko ^a   Higashida, Mayuko ^a   Nakayama, Taisuke ^a   Maxfield, Mark Webster ^a   Yoshida, Yasushi ^a   Shimabukuro, Michio ^a   Kitagawa, Tetsuya ^a   Sata, Masataka ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Aortic aneurysm; MR antagonist; Preventive medicine

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; EPLERENONE; GELATINASE A; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; MINERALOCORTICOID ANTAGONIST; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA ANEURYSM; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DRUG EFFICACY; DRUG SELECTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MODEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MACROPHAGE CULTURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE;

AORTIC ANEURYSM; MR ANTAGONIST; PREVENTIVE MEDICINE;

ANIMALS; AORTIC ANEURYSM; BLOOD PRESSURE; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION; INTERLEUKIN-6; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MINERALOCORTICOID RECEPTOR ANTAGONISTS; SPIRONOLACTONE; TUMOR NECROSIS FACTOR-ALPHA; VASCULITIS;

EID: 84886718839     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.05.002     Document Type: Article

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