Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase

Journal of Biological Chemistry

Volumn 288, Issue 43, 2013, Pages 31093-31104

  Rengachari, Srinivasan ^a   Aschauer, Philipp ^a   Schittmayer, Matthias ^b   Mayer, Nicole ^c   Gruber, Karl ^a   Breinbauer, Rolf ^c   Birner Gruenberger, Ruth ^b   Dreveny, Ingrid ^d   Oberer, Monika ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGE; CONFORMATIONAL PLASTICITY; DIFFERENT SUBSTRATES; HYDROLASE ACTIVITIES; HYDROLYTIC REACTIONS; SITE DIRECTED MUTAGENESIS; STRUCTURAL SIMILARITY; THREE-DIMENSIONAL STRUCTURE;

BACTERIOLOGY; BINDING ENERGY; BINDING SITES; CONFORMATIONS; HYDROLASES; LIGANDS; LIPASES; PLASTICITY; SUBSTRATES;

GLYCEROL;

ACYLGLYCEROL LIPASE; GLUTAMIC ACID; ISOLEUCINE;

ARTICLE; BACILLUS; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

CRYSTAL STRUCTURE; LIPASE; LIPID METABOLISM; LIPIDS; MGL; MONOACYLGLYCEROL; MONOGLYCERIDE; PHOSPHONATE INHIBITOR; SUBSTRATE ANALOGS; X-RAY CRYSTALLOGRAPHY;

BACILLUS; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROLYSIS; MONOACYLGLYCEROL LIPASES; MONOGLYCERIDES; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84886673603     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.491415     Document Type: Article

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