Methods of Mass Spectrometry in Homeland Security Applications

Mass Spectrometry Handbook

Volumn , Issue , 2012, Pages 417-439

  Laskay, Ünige A ^a   Kaleta, Erin J ^a   Wysocki, Vicki H ^a  

^a University of Arizona   (United States)

Author keywords

CWAs, health effects and relevant toxicity levels; Homeland security applications, and MS methods; Mass spectrometers in CWAs, and bacterial proteomic profiles; Novel approaches, MALDI TOF MS, PCR MS PCR ESI MS, SPME, FAME s, BAMS, CBMS; Proteomics based detection methods

Indexed keywords

EID: 84886672388     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118180730.ch19     Document Type: Chapter

References (57)

1. National Select Agent Registry ( .. ) Select agents and toxins list , http://www.selectagents.gov/select%20agents% 20and%20Toxins%20list.html , updated on Monday, September 19. 2011.
2. Hoenig , S.L. ( 2007 ) Compendium of Chemical Warfare Agents . New York: Springer .
3. D'Agostino , P.A. ( 2008 ) Forensic Science . Amsterdam, The Netherlands: Elsevier , pp. 839-872 .
4. Dietz , C. , Sanz , J. , Camara , C. ( 2006 ) Recent developments in solid-phase microextraction coatings and related techniques . Journal of Chromatography. A , 1103 , 183-192 .
5. Xu , L. , Basheer , C. , Lee , H.K. ( 2007 ) Developments in single-drop microextraction . Journal of Chromatography. A , 1152 , 184-192 .
6. Turner , C. , Eskilsson, C.S. , Bjorklund, E. ( 2002) Collection in analytical-scale supercritical fl uid extraction . Journal of Chromatography. A , 947 , 1-22 .
7. Cornish , T.J. , Antoine , M.D. , Ecelberger , S.A. , Demirev , P.A. ( 2005 ) Arrayed time-of-fl ight mass spectrometry for time-critical detection of hazardous agents . Analytical Chemistry , 77 , 3954-3959 .
8. Demirev , P.A. , Feldman , A.B. , Lin , J.S. ( 2004 ) Bioinformatics-based strategies for rapid microorganism identifi cation by mass spectrometry . Johns Hopkins APL Technical Digest , 25 , 27-37 .
9. Pineda , F.J. , Antoine , M.D. , Demirev , P.A. , Feldman , A.B. , Jackman, J. , Longenecker , M. , Lin, J.S. ( 2003) Microorganism identifi cation by matrix-assisted laser/desorption ionization mass spectrometry and model-derived ribosomal protein biomarkers . Analytical Chemistry , 75 , 3817-3822 .
10. Demirev , P.A. , Fenselau , C. ( 2008 ) Mass spectrometry in biodefense . Journal of Mass Spectrometry , 43 , 1441-1457 .
11. Anhalt , J.P. , Fenselau , C. ( 1975 ) Identifi cation of bacteria using mass spectrometry . Analytical Chemistry , 47 , 219-225 .
12. Claydon , M.A. , Davey , S.N. , Edwards-Jones , V. , Gordon , D.B. ( 1996 ) The rapid identifi cation of intact microorganisms using mass spectrometry . Nature Biotechnology , 14 , 1584-1586 .
13. Holland , R.D. , Wilkes , J.G. , Rafi i , F. , Sutherland , J.B. , Persons , C.C. , Voorhees , K.J. , Lay , J.O. Jr. ( 1996 ) Rapid identifi cation of intact whole bacteria based on spectral patterns using matrix-assisted laser desorption/ionization with time-of-fl ight mass spectrometry . Rapid Com munications in Mass Spectrometry , 10 , 1227-1232 .
14. Chen , P. , Lu , Y. , Harrington , P.B. ( 2008 ) Biomarker profi ling and reproducibility study of MALDI-MS measurements of Escherichia coli by analysis of variance-principal component analysis . Analytical Chemistry , 80 , 1474-1481 .
15. Valentine , N. , Wunschel , S. , Wunschel , D. , Petersen , C. , Wahl , K. ( 2005 ) Effect of culture conditions on microorganism identifi cation by matrix-assisted laser desorption ionization mass spectrometry . Applied and Environmental Microbiology , 71 , 58-64 .
16. Walker , J. , Fox , A.J. , Edwards-Jones , V. , Gordon , D.B. ( 2002 ) Intact cell mass spectrometry (ICMS) used to type methicillin-resistant Staphylococcus aureus: media effects and inter-laboratory reproducibility . Journal of Microbiological Methods , 48 , 117-126 .
17. Williams , T.L. , Andrzejewski , D. , Lay , J.O. Jr. , Musser , S.M. ( 2003 ) Experimental factors affecting the quality and reproducibility of MALDI TOF mass spectra obtained from whole bacteria cells . Journal of the American Society for Mass Spectrometry , 14 , 342-351 .
18. Wunschel , D.S. , Hill , E.A. , McLean , J.S. , Jarman , K. , Gorby , Y.A. , Valentine , N. , Wahl , K. ( 2005 ) Effects of varied pH, growth rate and temperature using controlled fermentation and batch culture on matrix assisted laser desorption/ ionization whole cell protein fi ngerprints . Journal of Microbiological Methods , 62 , 259-271 .
19. Arnold , R.J. , Karty , J.A. , Ellington , A.D. , Reilly , J.P. ( 1999 ) Monitoring the growth of a bacteria culture by MALDI-MS of whole cells . Analytical Chemistry , 71 , 1990-1996 .
20. Domin , M.A. , Welham , K.J. , Ashton , D.S. ( 1999 ) The effect of solvent and matrix combinations on the analysis of bacteria by matrix-assisted laser desorption/ionization time-of-fl ight mass spectrometry . Rapid Communications in Mass Spectrometry , 13 , 222-226 .
21. Jackson , K.A. , Edwards-Jones , V. , Sutton , C.W. , Fox , A.J. ( 2005 ) Optimisation of intact cell MALDI method for fi ngerprinting of methicillin-resistant Staphylococcus aureus . Journal of Microbiological Methods , 62 , 273-284 .
22. Mazzeo , M.F. , Sorrentino , A. , Gaita , M. , Cacace , G. , Di Stasio , M. , Facchiano , A. , Comi , G. , Malorni , A. , Siciliano , R.A. ( 2006 ) Matrix-assisted laser desorption ionization-time of fl ight mass spectrometry for the discrimination of food-borne microorganisms . Applied and Environmental Microbiology , 72 , 1180-1189 .
23. Wunschel , S.C. , Jarman , K.H. , Petersen , C.E. , Valentine , N.B. , Wahl , K.L. , Schauki , D. , Jackman , J. , Nelson , C.P. , White , E. ( 2005 ) Bacterial analysis by MALDI-TOF mass spectrometry: an inter-laboratory comparison . Journal of the American Society for Mass Spectrometry , 16 , 456-462 .
24. Jarman , K.H. , Cebula , S.T. , Saenz , A.J. , Petersen , C.E. , Valentine , N.B. , Kingsley , M.T. , Wahl , K.L. ( 2000 ) An algorithm for automated bacterial identifi cation using matrix-assisted laser desorption/ionization mass spectrometry . Analytical Chemistry , 72 , 1217-1223 .
25. Jarman , K.H. , Daly , D.S. , Petersen , C.E. , Saenz , A.J. , Valentine , N.B. , Wahl , K.L. ( 1999 ) Extracting and visualizing matrix-assisted laser desorption/ionization time-of-fl ight mass spectral fi ngerprints . Rapid Communications in Mass Spectrometry , 13 , 1586-1594 .
26. Jones , J.J. , Stump , M.J. , Fleming , R.C. , Lay , J.O. , Wilkins , C.L. ( 2003 ) Investigation of MALDI-TOF and FT-MS techniques for analysis of Escherichia coli whole cells . Analytical Chemistry , 75 , 1340-1347 .
27. Mellmann , A. , Cloud , J. , Maier , T. , Keckevoet , U. , Ramminger , I. , Iwen , P. , Dunn , J. , Hall , G. , Wilson , D. , LaSala , P. , Kostrzewa , M. , Harmsen , D. ( 2008 ) Evaluation of matrix-assisted laser desorption ionization-time-of-fl ight mass spectrometry in comparison to 16S rRNA gene sequencing for species identifi cation of nonfermenting bacteria . Journal of Clinical Microbiology , 46 , 1946-1954 .
28. Alispahic , M. , Hummel , K. , Jandreski-Cvetkovic , D. , Nobauer , K. , Razzazi-Fazeli , E. , Hess , M. , Hess , C. ( 2009 ) Species specifi c identifi cation and differentiation of Arcobacter , Helicobacter and Campylobacter by full-spectral MALDI-TOF MS analysis . Journal of Medical Microbiology , 59 , 295-301 .
29. Ilina , E.N. , Borovskaya , A.D. , Malakhova , M.M. , Vereshchagin , V.A. , Kubanova , A.A. , Kruglov , A.N. , Svistunova , T.S. , Gazarian , A.O. , Maier , T. , Kostrzewa , M. , Govorun , V.M. ( 2009 ) Direct bacterial profi ling by matrix-assisted laser desorption-ionization time-of-fl ight mass spectrometry for identifi cation of pathogenic Neisseria . The Journal of Molecular Diagnostics , 11 , 75-86 .
30. Mellmann , A. , Bimet , F. , Bizet , C. , Borovskaya , A.D. , Drake , R.R. , Eigner , U. , Fahr , A.M. , He , Y. , Ilina , E.N. , Kostrzewa , M. , Maier , T. , Mancinelli , L. , Moussaoui , W. , Prevost , G. , Putignani , L. , Seachord , C.L. , Tang , Y.W. , Harmsen , D. ( 2009 ) High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of fl ight mass spectrometry-based species identifi cation of nonfermenting bacteria . Journal of Clinical Microbiology , 47 , 3732-3734 .
31. van Wuijckhuijse , A.L. , Stowers , M.A. , Kleefsman , W.A. , van Baar , B.L.M. , Kientz , C.E. , Marijnissen , J.C.M. ( 2005 ) Matrix-assisted laser desorption/ionisation aerosol time-of-fl ight mass spectrometry for the analysis of bioaerosols: development of a fast detector for airborne biological pathogens . Journal of Aerosol Science , 36 , 677-687 .
32. Hofstadler , S.A. , Sampath , R. , Blyn , L.B. , Eshoo , M.W. , Hall , T.A. , Jiang , Y. , Drader , J.J. , Hannis , J.C. , Sannes-Lowery , K. , Cummins , L.L. , Libby , B. , Walcott , D.J. , Schink , A. , Massire , C. , Ranken , R. , Gutierrez , J. , Manalili , S. , Ivy , C. , Melton , R. , Levene , H. , Barrett-Wilt , G. , Li , F. , Zapp , V. , White , N. , Samant , V. , McNeil , J.A. , Knize , D. , Robbins , D. , Rudnick , K. , Desai , A. , Moradi , E. , Ecker , D.J. ( 2005 ) TIGER: the universal biosensor . International Journal of Mass Spectrometry , 242 , 23-41 .
33. Sampath , R. , Hofstadler , S.A. , Blyn , L.B. , Eshoo , M.W. , Hall , T.A. , Massire , C. , Levene , H.M. , Hannis , J.C. , Harrell , P.M. , Neuman , B. , Buchmeier , M.J. , Jiang , Y. , Ranken , R. , Drader , J.J. , Samant , V. , Griffey , R.H. , McNeil , J.A. , Crooke , S.T. , Ecker , D.J. ( 2005 ) Rapid identifi cation of emerging pathogens: coronavirus . Emerging Infectious Diseases , 11 , 373-379 .
34. Blyn , L.B. , Hall , T.A. , Libby , B. , Ranken , R. , Sampath , R. , Rudnick , K. , Moradi , E. , Desai , A. , Metzgar , D. , Russell , K.L. , Freed , N.E. , Balansay , M. , Broderick , M.P. , Osuna , M.A. , Hofstadler , S.A. , Ecker , D.J. ( 2008 ) Rapid detection and molecular serotyping of adenovirus by use of PCR followed by electrospray ionization mass spectrometry . Journal of Clinical Microbiology , 46 , 644-651 .
35. Sampath , R. , Russell , K.L. , Massire , C. , Eshoo , M.W. , Harpin , V. , Blyn , L.B. , Melton , R. , Ivy , C. , Pennella , T. , Li , F. , Levene , H. , Hall , T.A. , Libby , B. , Fan , N. , Walcott , D.J. , Ranken , R. , Pear , M. , Schink , A. , Gutierrez , J. , Drader , J. , Moore , D. , Metzgar , D. , Addington , L. , Rothman , R. , Gaydos , C.A. , Yang , S. , St George , K. , Fuschino , M.E. , Dean , A.B. , Stallknecht , D.E. , Goekjian , G. , Yingst , S. , Monteville , M. , Saad , M.D. , Whitehouse , C.A. , Baldwin , C. , Rudnick , K.H. , Hofstadler , S.A. , Lemon , S.M. , Ecker , D.J. ( 2007 ) Global surveillance of emerging Infl uenza virus genotypes by mass spectrometry . PloS ONE , 2 , e489 .
36. Darc é , K. ( 2009 ) " Carlsbad fi rm helped identify virus. Surveillance program tracks diseases along Mexico border . " The San Diego Union-Tribune , http://www. signonsandiego.com/news/2009/apr/28/1n28surveil001624-carlsbad-fi rm-helped-identify-vi/
37. Ecker , D.J. , Sampath , R. , Blyn , L.B. , Eshoo , M.W. , Ivy , C. , Ecker , J.A. , Libby , B. , Samant , V. , Sannes-Lowery , K.A. , Melton , R.E. , Russell , K. , Freed , N. , Barrozo , C. , Wu , J. , Rudnick , K. , Desai , A. , Moradi , E. , Knize , D.J. , Robbins , D.W. , Hannis , J.C. , Harrell , P.M. , Massire , C. , Hall , T.A. , Jiang , Y. , Ranken , R. , Drader , J.J. , White , N. , McNeil , J.A. , Crooke , S.T. , Hofstadler , S.A. ( 2005 ) Rapid identifi cation and strain-typing of respiratory pathogens for epidemic surveillance . Proceedings of the National Academy of Sciences of the United States of America , 102 , 8012-8017 .
38. Ecker , J.A. , Massire , C. , Hall , T.A. , Ranken , R. , Pennella , T.T. , Agasino , I.C. , Blyn , L.B. , Hofstadler , S.A. , Endy , T.P. , Scott , P.T. , Lindler , L. , Hamilton , T. , Gaddy , C. , Snow , K. , Pe , M. , Fishbain , J. , Craft , D. , Deye , G. , Riddell , S. , Milstrey , E. , Petruccelli , B. , Brisse , S. , Harpin , V. , Schink , A. , Ecker , D.J. , Sampath , R. , Eshoo , M.W. ( 2006 ) Identifi cation of Acinetobacter species and genotyping of Acinetobacter baumannii by multilocus PCR and mass spectrometry . Journal of Clinical Microbiology , 44 , 2921-2932 .
39. Hall , T.A. , Sampath , R. , Blyn , L.B. , Ranken , R. , Ivy , C. , Melton , R. , Matthews , H. , White , N. , Li , F. , Harpin , V. , Ecker , D.J. , McDougal , L.K. , Limbago , B. , Ross , T. , Wolk , D.M. , Wysocki , V. , Carroll , K.C. ( 2009 ) Rapid molecular genotyping and clonal complex assignment of Staphylococcus aureus isolates by PCR coupled to electrospray ionization-mass spectrometry . Journal of Clinical Microbiology , 47 , 1733-1741 .
40. Wolk , D.M. , Blyn , L.B. , Hall , T.A. , Sampath , R. , Ranken , R. , Ivy , C. , Melton , R. , Matthews , H. , White , N. , Li , F. , Harpin , V. , Ecker , D.J. , Limbago , B. , McDougal , L.K. , Wysocki , V.H. , Cai , M. , Carroll , K.C. ( 2009 ) Pathogen profi ling: rapid molecular characterization of Staphylococcus aureus by PCR/electrospray ionization-mass spectrometry and correlation with phenotype . Journal of Clinical Microbiology , 47 , 3129-3137 .
41. Eshoo , M.W. , Crowder , C.D. , Li , H. , Matthews , H.E. , Meng , S. , Sefers , S.E. , Sampath , R. , Stratton , C.W. , Blyn , L.B. , Ecker , D.J. , Tang , Y.W. ( 2009 ) Detection and identifi cation of Ehrlichia species in blood using PCR and electrospray ionization mass spectrometry . Journal of Clinical Microbiology , 48 , 472-478 .
42. Kaleta , E.J. , Clark , A.E. , Johnson , D.R. , Gamage , D.C. , Wysocki , V.H. , Cherkaou , A. , Schrenzel , J. , Wolk , D.M. ( 2011 ) Use of PCR coupled with electrospray ionization mass spectrometry for rapid identifi cation of bacterial and yeast bloodstream pathogens from blood culture bottles . Journal of Clinical Microbiology , 49 , 345-353 .
43. Beverly , M.B. , Basile , F. , Voorhees , K.J. , Hadfi eld , T.L. ( 1996 ) A rapid approach for the detection of dipicolinic acid in bacterial spores using pyrolysis/mass spectrometry . Rapid Communications in Mass Spectrometry , 10 , 455-458 .
44. Sasser , M. ( 1990 ) Identifi cation of bacteria by gas chromatography of cellular fatty acids . Tech. Note 101. Microbial ID, Inc., Newark, Delaware .
45. Buyer , J.S. ( 2003 ) Improved fast gas chromatography for FAME analysis of bacteria . Journal of Microbiological Methods , 54 , 117-120 .
46. Buyer , J.S. ( 2002 ) Rapid sample processing and fast gas chromatography for identifi cation of bacteria by fatty acid analysis . Journal of Microbiological Methods , 51 , 209-215 .
47. DeLuca , S. , Sarver , S.W. , Harrington , P.D. , Voorhees , K.J. ( 1990 ) Direct analysis of bacterial fatty acids by Curie-point pyrolysis tandem mass spectrometry . Analytical Chemistry , 62 , 1465-1472 .
48. Basile , F. , Beverly , M.B. , Abbas-Hawks , C. , Mowry , C.D. , Voorhees , K.J. , Hadfi eld , T.L. ( 1998 ) Direct mass spectrometric analysis of in situ thermally hydrolyzed and methylated lipids from whole bacterial cells . Analytical Chemistry , 70 , 1555-1562 .
49. Slabbinck , B. , De Baets , B. , Dawyndt , P. , De Vos , P. ( 2008 ) Genus-wide Bacillus species identifi cation through proper artifi cial neural network experiments on fatty acid profi les . Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology , 94 , 187-198 .
50. Slabbinck , B. , Waegeman , W. , Dawyndt , P. , De Vos , P. , De Baets , B. ( 2010 ) From learning taxonomies to phylogenetic learning: integration of 16S rRNA gene data into FAME-based bacterial classifi cation . BMC Bioinformatics , 11 , 69 .
51. Hart , K.J. , Wise , M.B. , Griest , W.H. , Lammert , S.A. ( 2000 ) Design, development, and performance of a fi eldable chemical and biological agent detector . Field Analytical Chemistry & Technology , 4 , 93-110 .
52. Fergenson , D.P. , Pitesky , M.E. , Tobias , H.J. , Steele , P.T. , Czerwieniec , G.A. , Russell , S.C. , Lebrilla , C.B. , Horn , J.M. , Coffee , K.R. , Srivastava , A. , Pillai , S.P. , Shih , M.T. , Hall , H.L. , Ramponi , A.J. , Chang , J.T. , Langlois , R.G. , Estacio , P.L. , Hadley , R.T. , Frank , M. , Gard , E.E. ( 2004 ) Reagentless detection and classifi cation of individual bioaerosol particles in seconds . Analytical Chemistry , 76 , 373-378 .
53. Russell , S.C. , Czerwieniec , G. , Lebrilla , C. , Steele , P. , Riot , V. , Coffee , K. , Frank , M. , Gard , E.E. ( 2005 ) Achieving high detection sensitivity (14 zmol) of biomolecular ions in bioaerosol mass spectrometry . Analytical Chemistry , 77 , 4734-4741 .
54. Czerwieniec , G.A. , Russell , S.C. , Lebrilla , C.B. , Coffee , K.R. , Riot , V. , Steele , P.T. , Frank , M. , Gard , E.E. ( 2005 ) Improved sensitivity and mass range in time-of-fl ight bioaerosol mass spectrometry using an electrostatic ion guide . Journal of the American Society for Mass Spectrometry , 16 , 1866-1875 .
55. Martin , A.N. , Farquar , G.R. , Frank , M. , Gard , E.E. , Fergenson , D.P. ( 2007 ) Single-particle aerosol mass spectrometry for the detection and identifi cation of chemical warfare agent simulants . Analytical Chemistry , 79 , 6368-6375 .
56. Sekiguchi , H. , Matsushita , K. , Yamashiro , S. , Sano , Y. , Seto , Y. , Okuda , T. , Sato , A. ( 2006 ) On-site determination of nerve and mustard gases using a fi eld-portable gas chromatograph-mass spectrometer . Forensic Toxicology , 24 , 17-22 .
57. Mowry , C.D. , Morgan , C.H. , Frye-Mason , G.C. , Theisen , L.A. , Trudell , D.E. , Baca , Q.J. , Chambers , W.C. , Martinez , J.I. ( 2003 ) Miniature sensors for biological warfare agents using fatty acid profi les . Ldrd 10775 Final Report, Sandia National Laboratories .