Continuous exposure to chrysotile asbestos can cause transformation of human mesothelial cells via HMGB1 and TNF-α signaling

American Journal of Pathology

Volumn 183, Issue 5, 2013, Pages 1654-1666

  Qi, Fang ^a,b   Okimoto, Gordon ^a   Jube, Sandro ^a   Napolitano, Andrea ^a,b   Pass, Harvey I ^d   Laczko, Rozalia ^a   Demay, Richard M ^e   Khan, Ghazal ^e   Tiirikainen, Maarit ^a   Rinaudo, Caterina ^f   Croce, Alessandro ^f   Yang, Haining ^a,c   Gaudino, Giovanni ^a   Carbone, Michele ^a,c  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^b UNIVERSITY OF HAWAII   (United States)

^c UNIVERSITY OF HAWAII   (United States)

^d NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^f UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHRYSOTILE; CROCIDOLITE; HIGH MOBILITY GROUP B1 PROTEIN; OLIGONUCLEOTIDE; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MESOTHELIUM CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ASBESTOS, CROCIDOLITE; ASBESTOS, SERPENTINE; BETA CATENIN; CADHERINS; CELL DEATH; CELL LINE; CELL SHAPE; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIUM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME, HUMAN; HMGB1 PROTEIN; HUMANS; MICE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84886661068     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.07.029     Document Type: Article

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