Insulin secretion and carbohydrate metabolism in patients with Laron syndrome: From hypoglycemia to diabetes mellitus

Laron Syndrome - From Man to Mouse: Lessons from Clinical and Experimental Experience

Volumn , Issue , 2011, Pages 259-272

  Laron, Zvi ^a  

^a SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84886642583     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-11183-9_30     Document Type: Chapter

References (19)

1. Dobbins RL, Cowley MA, Foster DW (2004) Glucose, lipid and protein metabolism. In: Griffin JE, Ojeda SR (eds) Textbook of endocrine physiology, 5th edn. Oxford University Press, New York, pp 377-406
2. Inokuchi N, Ikeda T, Yasuda F, Shirai S, Uchihori Y (1999) Severe proliferative diabetic retinopathy associated with acromegaly. Letter to the Editor. Br J Ophthalmol 83:628
3. Josefsberg Z, Vilunski E, Hanukuglu A, Bialik O, Brown M, Karp M, Laron Z (1976) Glucose and insulin responses to an oral glucose load in normal children and adolescents in Israel. Israel J Med Sci 12:189-194
4. Krsek M, Prazny M, Marek K, Skrha J, Justova V, Lacinova Z (2002) The relationship between serum levels of insulin like growth factor I and its binding proteins and microvascular function in acromegalic patients. Growth Horm IGF Res 12:54-59
5. Laron Z (1983) Deficiencies of growth hormone and somatomedins in man. Special Topics in Endocrinol Metab 5:149-199
6. Laron Z (1984) Laron type dwarfism (hereditary somatomedin deficiency): A review. In: Frick P, Von Harnack GA, Kochsiek K, Martini GA, Prader A, (eds) Advances in internal medicine and pediatrics. Springer, Berlin, pp 117-150
7. Laron Z (2002) Molecular mutations in the human growth hormone axis. In: Eugster EA, Pescovitz OH (eds) Contemporary endocrinology. Human Press, Totowa, pp 43-76
8. Laron Z (2008) Insulin - A growth hormone. Arch Physiol Biochem 114:11-16
9. Laron Z, Avizur Y, Klinger B (1995) Carbohydrate metabolism in primary growth hormone resistance (Laron syndrome) before and during insulin like growth factor I treatment. Metabolism 44:113-118
10. Laron Z, Avizur Y, Klinger B (1997) Insulin resistance in Laron syndrome (primary insulin like growth factor -I (IGF-I) deficiency) and effect of IGF-I replacement therapy. J Pediat Endocrinol Metab 10:105-115
11. Laron Z, Karp M (1980) Carbohydrate metabolism in the syndrome of familial dwarfism and high plasma immunoreactive growth hormone (Laron type dwarfism). In: Podolsky S, Viswanathan M (eds) Secondary diabetes: The spectrum of the diabetic syndromes. Raven Press, New York, pp 363-371
12. Laron Z, Pertzelan A, Mannheimer S (1966) Genetic pituitary dwarfism with high serum concentration of growth hormone. A new inborn error of metabolism? Israel J Med Sci 2: 152-155
13. Laron Z, Pertzelan A, Karp M (1968) Pituitary dwarfism with high serum levels of growth hormone. Israel J Med Sci 4: 883-894
14. Laron Z, Weinberger D (2004) Diabetic retinopathy in two patients with congenital IGF-I deficiency (Laron syndrome). Eur J Endocrinol 151:103-106
15. Laron Z, Weinberger D (2005) Diabetic retinopathy, nephropathy and cardiovascular disease in a patient with GH gene deletion (letter). Clin Endocrinol 63:699-700
16. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419
17. McAuley KA, Mann JI, Chase JG, Lotz TF, Shaw GM (2007) Point: HOMA - satisfactory for the time being. Diabetes Care 30:2411-2413
18. Unger RH, Aguilar-Parada E, Müller WA, Eisentraut AM (1970) Studies of pancreatic alpha cell function in normal and diabetic subjects. J Clin Invest 49:837-848
19. Wolfsdorf JI, Weinstein DA (2007) Hypoglycemia in children. In: Lifshitz F (ed) Pediatric endocrinology, 5th edn. Informa Health Care, New York, pp 291-327