Incidence, predictors, and outcome of intermediate syndrome in cholinergic insecticide poisoning: A prospective observational cohort study

Clinical Toxicology

Volumn 51, Issue 9, 2013, Pages 838-845

  Indira, M ^a   Andrews, M A ^a   Rakesh, T P ^a  

^a Government Medical College   (India)

Author keywords

Carbamate; Gastric lavage; GCS; IPCS PSS; Organophosphorus

Indexed keywords

CARBAMIC ACID; CHLORPYRIFOS; INSECTICIDE; ORGANOPHOSPHORUS COMPOUND; PARATHION METHYL;

ADULT; ARTICLE; CHEMICAL SAFETY; CHOLINERGIC INSECTICIDE POISONING; CLINICAL TRIAL; COHORT ANALYSIS; EXPOSURE; FEMALE; GLASGOW COMA SCALE; HOSPITAL ADMISSION; HUMAN; INTOXICATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MUSCLE WEAKNESS; NECK MUSCLE; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; RESPIRATORY FAILURE;

ADULT; AGED; ANTICHOLINERGIC SYNDROME; CARBAMATES; CHOLINERGIC ANTAGONISTS; COHORT STUDIES; FEMALE; HOSPITALS, UNIVERSITY; HUMANS; INCIDENCE; INDIA; INSECTICIDES; MALE; MIDDLE AGED; MUSCLE WEAKNESS; NECK MUSCLES; ORGANOPHOSPHATE POISONING; ORGANOPHOSPHATES; PROGNOSIS; RESPIRATORY INSUFFICIENCY; ROC CURVE; TERTIARY CARE CENTERS;

EID: 84886606617     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2013.837915     Document Type: Article

References (29)

1. Gunnell D, Eddleston M. Suicide by intentional ingestion of pesticides: A continuing tragedy in developing countries. Int J Epidemiol 2004; 33: 920.
2. Patel V, Ramasundarahettige C, Vijayakumar L, Thakur JS, Gajalakshmi V, Gururaj G. Suicide mortality in India: A nationally representative survey. Lancet 2012; 379: 2343-2351.
3. Munidasa UA, Gawarammana IB, Kularatne SA, Kumarasiri PV, Goonasekera CD. Survival pattern in patients with acute organophosphate poisoning receiving intensive care. J Toxicol Clin Toxicol 2004 ; 42: 343-347.
4. S enanayake N, K aralliedde L. N eurotoxic effects of organophosphorus insecticides. An intermediate syndrome. N Engl J Med 1987 ; 316: 761-763.
5. Jayawardane P, Dawson AH, Weerasinghe V, Karalliedde L, Buckley NA, Senanayake N. The spectrum of intermediate syndromefollowing acute organophosphate poisoning: A prospective cohort study from Sri Lanka. PLoS Med [online] 2008; 5:e147. Available at: Http:// www.plosmedicine.org/article/ info%3Adoi%2F10.1371%2Fjournal. pmed.0050147. Accessed on 2013 March 12
6. Q in F, X u H, C hen Y. I ntermediate syndrome after acute organophosphorus pesticides poisoning: Clinical analysis of 10 cases. Zhonghua nei ke za zhi [Chinese Journal of Internal Medicine] 1997; 36 : 613-616.
7. Dandapani M, Zachariah A, Kavitha MR, Jeyaseelan L, Oommen A. Oxidative damage in intermediate syndrome of acute organophosphorous poisoning. Indian J Med Res 2003; 117: 253-259.
8. Jayawardane P, Senanayake N, Buckley NA, Dawson AH. Electrophysiological correlates of respiratory failure in acute organophosphate poisoning: Evidence for differential roles of muscarinic and nicotinic stimulation. Clin Toxicol (Phila) [online] 2012; 50: 250-253. Available at: Http://www.ncbi.nlm.nih.gov/ pubmed/22455356. Accessed on 2013 February 24.
9. K aralliedde L, B aker D, M arrs T C. O rganophosphate-induced intermediate syndrome: Aetiology and relationships with myopathy. Toxicol Rev 2006; 25: 1-14.
10. D awson A H, E ddleston M, S enarathna L, M ohamed F, G awarammana I, Bowe SJ, et al. Acute human lethal toxicity of agricultural pesticides: A prospective cohort study. PLoS Med [online] 2010; 7:e1000357. Available at: Http://www.ncbi.nlm.nih.gov/pubmed/e1000357. Accessed on 2013 March 13.
11. Benfenati E, Gini G, Piclin N, Roncaglioni A, Var ì MR. Predicting logP of pesticides using different software. Chemosphere 2003; 53: 1155-1164.
12. Srinivas Rao C, Venkateswarlu V, Surender T, Eddleston M, Buckley NA. Pesticide poisoning in south India: Opportunities for prevention and improved medical management. Trop Med Int Health 2005; 10: 581-588.
13. Banerjee I, Tripathi S, Roy AS. Clinico-epidemiological characteristics of patients presenting with organophosphorus poisoning. N Am J Med Sci 2012; 4: 147-150.
14. Thunga G, Sam KG, Khera K, Pandey S, Vidya S. Evaluation of incidence, clinical characteristics and management in organophosphorus poisoning patients in a tertiary care hospital. J Toxicol Environ Health Sci 2010; 2: 73-76.
15. De Bleecker J, Van den Neucker K, Colardyn F. Intermediate syndrome in organophosphorus poisoning: A prospective study. Crit Care Med 1993; 21: 1706-1711.
16. Yang CC, Deng JF. Intermediate syndrome following organophosphate insecticide poisoning. J Chin Med Assoc 2007 ; 70: 467-72.
17. Tsao TC, Juang YC, Lan RS, Shieh WB, Lee CH. Respiratory failure of acute organophosphate and carbamate poisoning. Chest 1990; 98: 631-636.
18. Paul N, Mannathukkaran TJ. Intermediate syndrome following carbamate poisoning. Clin Toxicol (Phila) 2005; 43: 867-868.
19. Eddleston M, Eyer P, Worek F, Mohamed F, Senarathna L, Von Meyer L, et al. Differences between organophosphorus insecticides in human self-poisoning: A prospective cohort study. Lancet 2005; 366: 1452-1459.
20. Peter JV, Jerobin J, Nair A, Bennett A, Samuel P, Chrispal A, et al. Clinical profi le and outcome of patients hospitalized with dimethyl and diethyl organophosphate poisoning. Clin Toxicol (Phila) 2010 ; 48: 916-923.
21. V ijaya S, S udhakar Y, V enkateswarlu B. C urrent review on organophosphorus poisoning. Arch Appl Sci Res 2010; 2: 199-215.
22. Eddleston M, Dawson A, Karalliedde L, Dissanayake W, Hittarage A, Azher S, Buckley NA. Early management after self-poisoning with an organophosphorus or carbamate pesticide-A treatment protocol for junior doctors. Crit Care 2004; 8: R391-R397.
23. Eddleston M, Mohamed F, Davies JOJ, Eyer P, Worek F, Sheriff MHR, Buckley NA. Respiratory failure in acute organophosphorus pesticide self-poisoning. QJM 2006; 99: 513-522.
24. Li Y, Tse ML, Gawarammana I, Buckley N, Eddleston M. Systematic review of controlled clinical trials of gastric lavage in acute organophosphorus pesticide poisoning. Clin Toxicol (Phila) 2009; 47: 179-192.
25. Benson BE, Hoppu K, Troutman WG, Bedry R, Erdman A, H ö jer J, et al. Position paper update: Gastric lavage for gastrointestinal decontamination. Clin Toxicol (Phila) 2013; 51: 140-146.
26. Li Y, Yu X, Wang Z, Wang H, Zhao X, Cao Y, et al. Gastric lavage in acute organophosphorus pesticide poisoning (GLAOP)-A randomised controlled trial of multiple vs. single gastric lavage in unselected acute organophosphorus insecticide poisoning. BMC Emerg Med 2006; 6: 10.
27. Kang EJ, Seok SJ, Lee KH, Gil HW, Yang JO, Lee EY, Hong SY. Factors for determining survival in acute organophosphate poisoning. Korean J Intern Med 2009; 24: 362-367.
28. Casey PB, Dexter EM, Michell J, Vale JA. The prospective value of the IPCS/EC/EAPCCT poisoning severity score in cases of poisoning. J Toxicol Clin Toxicol 1998; 36: 215-217.
29. Davies JOJ, Eddleston M, Buckley NA. Predicting outcome in acute organophosphorus poisoning with a poison severity score or the Glasgow coma scale. QJM 2008; 101: 371-379.