-
1
-
-
84875459651
-
Computational drug repositioning: From data to therapeutics
-
Hurle, M.R., Yang, L., Xie, Q., Rajpal, D.K., Sanseau, P., Agarwal, P.: Computational drug repositioning: from data to therapeutics. Clin. Pharmacol. Ther. 93(4), 335-341 (2013)
-
(2013)
Clin. Pharmacol. Ther.
, vol.93
, Issue.4
, pp. 335-341
-
-
Hurle, M.R.1
Yang, L.2
Xie, Q.3
Rajpal, D.K.4
Sanseau, P.5
Agarwal, P.6
-
2
-
-
4344668661
-
Drug Repositioning: Identifying and Developing New Uses for Existing Drugs
-
Ashburn, T.T., Thor, K.B.: Drug Repositioning: Identifying and Developing New Uses for Existing Drugs. Nature Reviews Drug Discovery 3, 645-646 (2004)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, pp. 645-646
-
-
Ashburn, T.T.1
Thor, K.B.2
-
3
-
-
79960775459
-
Drug repositioning for orphan diseases
-
Sardana, D., Zhu, C., Zhang, M., Gudivada, R.C., Yang, L., Jegga, A.G.: Drug repositioning for orphan diseases. Brief Bioinform 12(4), 346-356 (2011)
-
(2011)
Brief Bioinform
, vol.12
, Issue.4
, pp. 346-356
-
-
Sardana, D.1
Zhu, C.2
Zhang, M.3
Gudivada, R.C.4
Yang, L.5
Jegga, A.G.6
-
4
-
-
70449634957
-
Predicting new molecular targets for known drugs
-
Keiser, M.J., Setola, V., Irwin, J.J., Laggner, C., Abbas, A.I., Hufeisen, S.J., Jensen, N.H., Kuijer, M.B., Matos, R.C., Tran, T.B., Whaley, R., Glennon, R.A., Hert, J., Thomas, K.L., Edwards, D.D., Shoichet, B.K., Roth, B.L.: Predicting new molecular targets for known drugs. Nature 462, 175-181 (2009)
-
(2009)
Nature
, vol.462
, pp. 175-181
-
-
Keiser, M.J.1
Setola, V.2
Irwin, J.J.3
Laggner, C.4
Abbas, A.I.5
Hufeisen, S.J.6
Jensen, N.H.7
Kuijer, M.B.8
Matos, R.C.9
Tran, T.B.10
Whaley, R.11
Glennon, R.A.12
Hert, J.13
Thomas, K.L.14
Edwards, D.D.15
Shoichet, B.K.16
Roth, B.L.17
-
5
-
-
68249111344
-
Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts
-
Li, J., Zhu, X., Chen, J.Y.: Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts. PLoS Comput. Biol. 5(7), e1000450 (2009)
-
(2009)
PLoS Comput. Biol.
, vol.5
, Issue.7
-
-
Li, J.1
Zhu, X.2
Chen, J.Y.3
-
6
-
-
77953682031
-
Computational approaches for drug repositioning and combination therapy design
-
Kotelnikova, E., Yuryev, A., Mazo, I., Daraselia, N.: Computational approaches for drug repositioning and combination therapy design. J. Bioinform Comput. Biol. 8(3), 593-606 (2010)
-
(2010)
J. Bioinform Comput. Biol.
, vol.8
, Issue.3
, pp. 593-606
-
-
Kotelnikova, E.1
Yuryev, A.2
Mazo, I.3
Daraselia, N.4
-
7
-
-
47249146126
-
Drug target identification using side-effect similarity
-
Campillos, M., Kuhn, M., Gavin, A.C., Jensen, L.J., Bork, P.: Drug target identification using side-effect similarity. Science 321, 263-266 (2008)
-
(2008)
Science
, vol.321
, pp. 263-266
-
-
Campillos, M.1
Kuhn, M.2
Gavin, A.C.3
Jensen, L.J.4
Bork, P.5
-
8
-
-
83755163958
-
Systematic Drug Repositioning Based on Clinical Side-Effects
-
Yang, L., Agarwal, P.: Systematic Drug Repositioning Based on Clinical Side-Effects. PLoS ONE 6(12), e28025 (2011)
-
(2011)
PLoS ONE
, vol.6
, Issue.12
-
-
Yang, L.1
Agarwal, P.2
-
9
-
-
68449088145
-
Human Disease-Drug Network Based on Genomic Expression Profiles
-
Hu, G., Agarwal, P.: Human Disease-Drug Network Based on Genomic Expression Profiles. PLoS ONE 4(8), e6536 (2009)
-
(2009)
PLoS ONE
, vol.4
, Issue.8
-
-
Hu, G.1
Agarwal, P.2
-
10
-
-
84867338003
-
Discovery and preclinical validation of drug indications using compendia of public gene expression data
-
Sirota, M., Dudley, J.T., Kim, J., Chiang, A.P., Morgan, A.A., Sweet-Cordero, A., Sage, J., Butte, A.J.: Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci. Transl. Med. 3(96), 96ra77 (2011)
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.96
-
-
Sirota, M.1
Dudley, J.T.2
Kim, J.3
Chiang, A.P.4
Morgan, A.A.5
Sweet-Cordero, A.6
Sage, J.7
Butte, A.J.8
-
11
-
-
79959926410
-
DRAR-CPI: A server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome
-
Luo, H., Chen, J., Shi, L., Mikailov, M., Zhu, H., Wang, K., He, L., Yang, L.: DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome. Nucleic Acids Res. 39(Web Server Issue), W492-W498 (2011)
-
(2011)
Nucleic Acids Res.
, vol.39
, Issue.WEB SERVER ISSUE
-
-
Luo, H.1
Chen, J.2
Shi, L.3
Mikailov, M.4
Zhu, H.5
Wang, K.6
He, L.7
Yang, L.8
-
13
-
-
79958754253
-
PREDICT: A method for inferring novel drug indications with application to personalized medicine
-
Gottlieb, A., Stein, G.Y., Ruppin, E., Sharan, R.: PREDICT: a method for inferring novel drug indications with application to personalized medicine. Mol. Syst. Biol. 7, 496 (2011)
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 496
-
-
Gottlieb, A.1
Stein, G.Y.2
Ruppin, E.3
Sharan, R.4
-
14
-
-
0000107975
-
Relations between two sets of variates
-
Hotelling, H.: Relations between two sets of variates. Biometrika 28, 321-377 (1936)
-
(1936)
Biometrika
, vol.28
, pp. 321-377
-
-
Hotelling, H.1
-
16
-
-
67849104638
-
PubChem: A public information system for analyzing bioactivities of small molecules
-
Wang, Y., Xiao, J., Suzek, T.O., Zhang, J., Wang, J., Bryant, S.H.: PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res. 37(Web Server Issue), W623-W633 (2009)
-
(2009)
Nucleic Acids Res.
, vol.37
, Issue.WEB SERVER ISSUE
-
-
Wang, Y.1
Xiao, J.2
Suzek, T.O.3
Zhang, J.4
Wang, J.5
Bryant, S.H.6
-
17
-
-
0037361967
-
The Chemistry Development Kit (CDK): An open-source Java library for Chemo- and Bioinformatics
-
Steinbeck, C., Han, Y., Kuhn, S., Horlacher, O., Luttmann, E., Willighagen, E.: The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics. J. Chem. Inf. Comput. Sci. 43(2), 493-500 (2003)
-
(2003)
J. Chem. Inf. Comput. Sci.
, vol.43
, Issue.2
, pp. 493-500
-
-
Steinbeck, C.1
Han, Y.2
Kuhn, S.3
Horlacher, O.4
Luttmann, E.5
Willighagen, E.6
-
18
-
-
0022431785
-
The statistical distribution of nucleic acid similarities
-
Smith, T.F., Waterman, M.S., Burks, C.: The statistical distribution of nucleic acid similarities. Nucleic Acids Res. 13, 645-656 (1985)
-
(1985)
Nucleic Acids Res.
, vol.13
, pp. 645-656
-
-
Smith, T.F.1
Waterman, M.S.2
Burks, C.3
-
19
-
-
76149120425
-
A side effect resource to capture phenotypic effects of drugs
-
Kuhn, M., Campillos, M., Letunic, I., Jensen, L.J., Bork, P.: A side effect resource to capture phenotypic effects of drugs. Molecular Systems Biology 6, 343 (2010)
-
(2010)
Molecular Systems Biology
, vol.6
, pp. 343
-
-
Kuhn, M.1
Campillos, M.2
Letunic, I.3
Jensen, L.J.4
Bork, P.5
-
20
-
-
79955969387
-
Predicting drug side-effect profiles: A chemical fragment-based approach
-
Pauwels, E., Stoven, V., Yamanishi, Y.: Predicting drug side-effect profiles: a chemical fragment-based approach. BMC Bioinformatics 12, 169 (2011)
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 169
-
-
Pauwels, E.1
Stoven, V.2
Yamanishi, Y.3
-
21
-
-
67650898284
-
Incorporating functional inter-relationships into protein function prediction algorithms
-
Pandey, G., Myers, C.L., Kumar, V.: Incorporating functional inter-relationships into protein function prediction algorithms. BMC Bioinformatics 10, 142 (2009)
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 142
-
-
Pandey, G.1
Myers, C.L.2
Kumar, V.3
-
22
-
-
38549151817
-
DrugBank: A knowledgebase for drugs, drug actions and drug targets
-
Wishart, D.S., Knox, C., Guo, A.C., Cheng, D., Shrivastava, S., Tzur, D., Gautam, B., Hassanali, M.: DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 36(Database Issue), D901-D906 (2008)
-
(2008)
Nucleic Acids Res.
, vol.36
, Issue.DATABASE ISSUE
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Cheng, D.4
Shrivastava, S.5
Tzur, D.6
Gautam, B.7
Hassanali, M.8
-
23
-
-
0345863927
-
The Unified Medical Language System (UMLS): Integrating biomedical terminology
-
Olivier, B.: The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res. 32(Database Issue), D267-D270 (2004)
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.DATABASE ISSUE
-
-
Olivier, B.1
-
24
-
-
9144232912
-
UniProt: The Universal Protein knowledgebase
-
Apweiler, R., Bairoch, A., Wu, C.H., Barker, W.C., Boeckmann, B., Ferro, S., Gasteiger, E., Huang, H., Lopez, R., Magrane, M., Martin, M.J., Natale, D.A., O'Donovan, C., Redaschi, N., Yeh, L.S.: UniProt: the Universal Protein knowledgebase. Nucleic Acids Res. 32(Database Issue), D115-D119 (2004)
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.DATABASE ISSUE
-
-
Apweiler, R.1
Bairoch, A.2
Wu, C.H.3
Barker, W.C.4
Boeckmann, B.5
Ferro, S.6
Gasteiger, E.7
Huang, H.8
Lopez, R.9
Magrane, M.10
Martin, M.J.11
Natale, D.A.12
O'Donovan, C.13
Redaschi, N.14
Yeh, L.S.15
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