메뉴 건너뛰기




Volumn 8190 LNAI, Issue PART 3, 2013, Pages 579-594

Computational drug repositioning by ranking and integrating multiple data sources

Author keywords

Drug Indication Prediction; Drug Repositioning; Large Margin Method; Metric Integration; Multiple Data Sources

Indexed keywords

COMPUTATIONAL FRAMEWORK; DRUG REPOSITIONING; INFORMATION SOURCES; LARGE MARGIN METHODS; LARGE-SCALE STUDIES; MULTIPLE DATA SOURCES; SIMILARITY MEASURE; WEIGHTED K-NEAREST NEIGHBORS;

EID: 84886569335     PISSN: 03029743     EISSN: 16113349     Source Type: Book Series    
DOI: 10.1007/978-3-642-40994-3_37     Document Type: Conference Paper
Times cited : (39)

References (25)
  • 2
    • 4344668661 scopus 로고    scopus 로고
    • Drug Repositioning: Identifying and Developing New Uses for Existing Drugs
    • Ashburn, T.T., Thor, K.B.: Drug Repositioning: Identifying and Developing New Uses for Existing Drugs. Nature Reviews Drug Discovery 3, 645-646 (2004)
    • (2004) Nature Reviews Drug Discovery , vol.3 , pp. 645-646
    • Ashburn, T.T.1    Thor, K.B.2
  • 5
    • 68249111344 scopus 로고    scopus 로고
    • Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts
    • Li, J., Zhu, X., Chen, J.Y.: Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts. PLoS Comput. Biol. 5(7), e1000450 (2009)
    • (2009) PLoS Comput. Biol. , vol.5 , Issue.7
    • Li, J.1    Zhu, X.2    Chen, J.Y.3
  • 6
    • 77953682031 scopus 로고    scopus 로고
    • Computational approaches for drug repositioning and combination therapy design
    • Kotelnikova, E., Yuryev, A., Mazo, I., Daraselia, N.: Computational approaches for drug repositioning and combination therapy design. J. Bioinform Comput. Biol. 8(3), 593-606 (2010)
    • (2010) J. Bioinform Comput. Biol. , vol.8 , Issue.3 , pp. 593-606
    • Kotelnikova, E.1    Yuryev, A.2    Mazo, I.3    Daraselia, N.4
  • 7
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • Campillos, M., Kuhn, M., Gavin, A.C., Jensen, L.J., Bork, P.: Drug target identification using side-effect similarity. Science 321, 263-266 (2008)
    • (2008) Science , vol.321 , pp. 263-266
    • Campillos, M.1    Kuhn, M.2    Gavin, A.C.3    Jensen, L.J.4    Bork, P.5
  • 8
    • 83755163958 scopus 로고    scopus 로고
    • Systematic Drug Repositioning Based on Clinical Side-Effects
    • Yang, L., Agarwal, P.: Systematic Drug Repositioning Based on Clinical Side-Effects. PLoS ONE 6(12), e28025 (2011)
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Yang, L.1    Agarwal, P.2
  • 9
    • 68449088145 scopus 로고    scopus 로고
    • Human Disease-Drug Network Based on Genomic Expression Profiles
    • Hu, G., Agarwal, P.: Human Disease-Drug Network Based on Genomic Expression Profiles. PLoS ONE 4(8), e6536 (2009)
    • (2009) PLoS ONE , vol.4 , Issue.8
    • Hu, G.1    Agarwal, P.2
  • 11
    • 79959926410 scopus 로고    scopus 로고
    • DRAR-CPI: A server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome
    • Luo, H., Chen, J., Shi, L., Mikailov, M., Zhu, H., Wang, K., He, L., Yang, L.: DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome. Nucleic Acids Res. 39(Web Server Issue), W492-W498 (2011)
    • (2011) Nucleic Acids Res. , vol.39 , Issue.WEB SERVER ISSUE
    • Luo, H.1    Chen, J.2    Shi, L.3    Mikailov, M.4    Zhu, H.5    Wang, K.6    He, L.7    Yang, L.8
  • 13
    • 79958754253 scopus 로고    scopus 로고
    • PREDICT: A method for inferring novel drug indications with application to personalized medicine
    • Gottlieb, A., Stein, G.Y., Ruppin, E., Sharan, R.: PREDICT: a method for inferring novel drug indications with application to personalized medicine. Mol. Syst. Biol. 7, 496 (2011)
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 496
    • Gottlieb, A.1    Stein, G.Y.2    Ruppin, E.3    Sharan, R.4
  • 14
    • 0000107975 scopus 로고
    • Relations between two sets of variates
    • Hotelling, H.: Relations between two sets of variates. Biometrika 28, 321-377 (1936)
    • (1936) Biometrika , vol.28 , pp. 321-377
    • Hotelling, H.1
  • 16
    • 67849104638 scopus 로고    scopus 로고
    • PubChem: A public information system for analyzing bioactivities of small molecules
    • Wang, Y., Xiao, J., Suzek, T.O., Zhang, J., Wang, J., Bryant, S.H.: PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res. 37(Web Server Issue), W623-W633 (2009)
    • (2009) Nucleic Acids Res. , vol.37 , Issue.WEB SERVER ISSUE
    • Wang, Y.1    Xiao, J.2    Suzek, T.O.3    Zhang, J.4    Wang, J.5    Bryant, S.H.6
  • 17
    • 0037361967 scopus 로고    scopus 로고
    • The Chemistry Development Kit (CDK): An open-source Java library for Chemo- and Bioinformatics
    • Steinbeck, C., Han, Y., Kuhn, S., Horlacher, O., Luttmann, E., Willighagen, E.: The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics. J. Chem. Inf. Comput. Sci. 43(2), 493-500 (2003)
    • (2003) J. Chem. Inf. Comput. Sci. , vol.43 , Issue.2 , pp. 493-500
    • Steinbeck, C.1    Han, Y.2    Kuhn, S.3    Horlacher, O.4    Luttmann, E.5    Willighagen, E.6
  • 18
    • 0022431785 scopus 로고
    • The statistical distribution of nucleic acid similarities
    • Smith, T.F., Waterman, M.S., Burks, C.: The statistical distribution of nucleic acid similarities. Nucleic Acids Res. 13, 645-656 (1985)
    • (1985) Nucleic Acids Res. , vol.13 , pp. 645-656
    • Smith, T.F.1    Waterman, M.S.2    Burks, C.3
  • 20
    • 79955969387 scopus 로고    scopus 로고
    • Predicting drug side-effect profiles: A chemical fragment-based approach
    • Pauwels, E., Stoven, V., Yamanishi, Y.: Predicting drug side-effect profiles: a chemical fragment-based approach. BMC Bioinformatics 12, 169 (2011)
    • (2011) BMC Bioinformatics , vol.12 , pp. 169
    • Pauwels, E.1    Stoven, V.2    Yamanishi, Y.3
  • 21
    • 67650898284 scopus 로고    scopus 로고
    • Incorporating functional inter-relationships into protein function prediction algorithms
    • Pandey, G., Myers, C.L., Kumar, V.: Incorporating functional inter-relationships into protein function prediction algorithms. BMC Bioinformatics 10, 142 (2009)
    • (2009) BMC Bioinformatics , vol.10 , pp. 142
    • Pandey, G.1    Myers, C.L.2    Kumar, V.3
  • 23
    • 0345863927 scopus 로고    scopus 로고
    • The Unified Medical Language System (UMLS): Integrating biomedical terminology
    • Olivier, B.: The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res. 32(Database Issue), D267-D270 (2004)
    • (2004) Nucleic Acids Res. , vol.32 , Issue.DATABASE ISSUE
    • Olivier, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.