The CXCR4 mutations in WHIM syndrome impair the stability of the T-cell immunologic synapse

Blood

Volumn 122, Issue 5, 2013, Pages 666-673

  Kallikourdis, Marinos ^a,b   Trovato, Anna Elisa ^a   Anselmi, Fabio ^a   Sarukhan, Adelaida ^a,c   Roselli, Giuliana ^a   Tassone, Laura ^d   Badolato, Raffaele ^d   Viola, Antonella ^a,b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c ERI 23   (France)

^d Laboratory of Genetic Disorders of Childhood   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CXCR4 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CELL INTERACTION; CELLULAR IMMUNITY; CELLULAR PARAMETERS; CONJUGATE; CONTROLLED STUDY; EX VIVO STUDY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN DEFICIENCY; IMMUNOLOGICAL SYNAPSE; INFECTION; INHIBITION KINETICS; LYMPH NODE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TIME-LAPSE VIDEO MICROSCOPY; VERRUCA VULGARIS; WART HYPOGAMMAGLOBULINEMIA INFECTION MYELOKATHEXIS SYNDROME; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; FEMALE; GENETICS; IMMUNE DEFICIENCY; IMMUNOLOGY; MALE; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TRANSPORT; TRANSGENIC MOUSE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; FEMALE; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGICAL SYNAPSES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, CXCR4; T-LYMPHOCYTES; WARTS;

EID: 84886559702     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-461830     Document Type: Article

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