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Volumn , Issue , 2010, Pages 155-174

Genomic Basis of Anti-Inflammatory Properties of Boswellia Extract

Author keywords

Gene chip probe array analysis; Genetic Basis for Efficacy of BE 30; Genetic Basis of Anti Inflammatory Properties of Boswellia Extract; Human Clinical Studies Validate Gene Chip Studies; Lequesne functional index (LFI); TNF induced MMP 3 protein expression; Western Ontario and McMaster Universities (WOMAC)

Indexed keywords


EID: 84886552475     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780813821474.ch11     Document Type: Chapter
Times cited : (1)

References (41)
  • 2
    • 0029975669 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases-1 and -2
    • Smith, W. L., Dewitt, D. L., Prostaglandin endoperoxide H synthases-1 and -2. Adv Immunol 1996, 62, 167-215.
    • (1996) Adv Immunol , vol.62 , pp. 167-215
    • Smith, W.L.1    Dewitt, D.L.2
  • 3
    • 0026480564 scopus 로고
    • Mammalian lipoxygenases: molecular structures and functions
    • Yamamoto, S., Mammalian lipoxygenases: molecular structures and functions. Biochim Biophys Acta 1992, 1128, 117-131.
    • (1992) Biochim Biophys Acta , vol.1128 , pp. 117-131
    • Yamamoto, S.1
  • 4
    • 18744368220 scopus 로고    scopus 로고
    • Boswellia: An evidence-based systematic review by the natural standard research collaboration
    • Ethan, B., Heather, B., Theresa, D. H., Ivo, F., et al., Boswellia: An evidence-based systematic review by the natural standard research collaboration. J Herb Pharmacother 2004, 4, 63-83.
    • (2004) J Herb Pharmacother , vol.4 , pp. 63-83
    • Ethan, B.1    Heather, B.2    Theresa, D.H.3    Ivo, F.4
  • 6
    • 0025922660 scopus 로고
    • Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata.
    • Ammon, H. P., Mack, T., Singh, G. B., Safayhi, H., Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata. Planta Med 1991, 57, 203-207.
    • (1991) Planta Med , vol.57 , pp. 203-207
    • Ammon, H.P.1    Mack, T.2    Singh, G.B.3    Safayhi, H.4
  • 7
    • 0022446751 scopus 로고
    • Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent.
    • Singh, G. B., Atal, C. K., Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent. Agents Actions 1986, 18, 407-412.
    • (1986) Agents Actions , vol.18 , pp. 407-412
    • Singh, G.B.1    Atal, C.K.2
  • 8
    • 0036360009 scopus 로고    scopus 로고
    • Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases
    • Ammon, H. P. T., Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases. Wien Med Wochenschr 2002, 152, 373-378.
    • (2002) Wien Med Wochenschr , vol.152 , pp. 373-378
    • Ammon, H.P.T.1
  • 9
    • 0037282674 scopus 로고    scopus 로고
    • Efficacy and tolerability of Boswellia serrata in treatment of osteoartritis of knee-A randomized double blind placebo controlled trial
    • Kimmatkar, N., Thawani, V., Hingorani, L., Khiyani, R., Efficacy and tolerability of Boswellia serrata in treatment of osteoartritis of knee-A randomized double blind placebo controlled trial. Phytomedicine 2003, 10, 3-7.
    • (2003) Phytomedicine , vol.10 , pp. 3-7
    • Kimmatkar, N.1    Thawani, V.2    Hingorani, L.3    Khiyani, R.4
  • 10
    • 0034941316 scopus 로고    scopus 로고
    • Effects of gum resin of Boswellia serrata in patients with chronic colitis
    • Gupta, I., Parihar, A., Malhotra, P., Gupta, S., et al., Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001, 67, 391-395.
    • (2001) Planta Med , vol.67 , pp. 391-395
    • Gupta, I.1    Parihar, A.2    Malhotra, P.3    Gupta, S.4
  • 11
    • 0030639918 scopus 로고    scopus 로고
    • Effects of Boswellia serrata gum resin in patients with ulcerative colitis
    • Gupta, I., Parihar, A., Malhotra, P., Singh, G. B., et al., Effects of Boswellia serrata gum resin in patients with ulcerative colitis. Eur J Med Res 1997, 2, 37-43.
    • (1997) Eur J Med Res , vol.2 , pp. 37-43
    • Gupta, I.1    Parihar, A.2    Malhotra, P.3    Singh, G.B.4
  • 12
    • 0035145357 scopus 로고    scopus 로고
    • Therapy of active Crohn disease with Boswellia serrata extract H15
    • Gerhardt, H., Seifert, F., Buvari, P., Vogelsang, H., et al., Therapy of active Crohn disease with Boswellia serrata extract H15. Z Gastroenterol 2001, 39, 11-17.
    • (2001) Z Gastroenterol , vol.39 , pp. 11-17
    • Gerhardt, H.1    Seifert, F.2    Buvari, P.3    Vogelsang, H.4
  • 13
    • 0032541951 scopus 로고    scopus 로고
    • Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study
    • Gupta, I., Gupta, V., Parihar, A., Gupta, S., et al., Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998, 3, 511-514.
    • (1998) Eur J Med Res , vol.3 , pp. 511-514
    • Gupta, I.1    Gupta, V.2    Parihar, A.3    Gupta, S.4
  • 14
    • 0031440035 scopus 로고    scopus 로고
    • Anti-inflammatory actions of pentacyclic triterpenes
    • Safayhi, H., Sailer, E. R., Anti-inflammatory actions of pentacyclic triterpenes. Planta Med 1997, 63, 487-493.
    • (1997) Planta Med , vol.63 , pp. 487-493
    • Safayhi, H.1    Sailer, E.R.2
  • 15
    • 0000211539 scopus 로고
    • B-boswellic acid, acetyl-b-boswellic acid, acetyl-11-keto-b-boswellic acid & 11-keto-b-boswellic acid and four pentacyclic triterpene acids from the resin of s Roxb.
    • Pardhy, R. S., Bhattacharya, S. C., B-boswellic acid, acetyl-b-boswellic acid, acetyl-11-keto-b-boswellic acid & 11-keto-b-boswellic acid and four pentacyclic triterpene acids from the resin of s Roxb. Indian J Chem 1978, 16B, 176-178.
    • (1978) Indian J Chem , vol.16 , pp. 176-178
    • Pardhy, R.S.1    Bhattacharya, S.C.2
  • 16
    • 0030973083 scopus 로고    scopus 로고
    • Inhibition by boswellic acids of human leukocyte elastase
    • Safayhi, H., Rall, B., Sailer, E. R., Ammon, H. P. T., Inhibition by boswellic acids of human leukocyte elastase. J Pharmacol Exp Ther 1997, 281, 460-463.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 460-463
    • Safayhi, H.1    Rall, B.2    Sailer, E.R.3    Ammon, H.P.T.4
  • 17
    • 2942574275 scopus 로고    scopus 로고
    • Drugs that target lipoxygenases and leukotrienes as emerging therapies for asthma and cancer
    • Poff, C. D., Balazy, M., Drugs that target lipoxygenases and leukotrienes as emerging therapies for asthma and cancer. Curr Drug Targets Inflamm Allergy 2004, 3, 19-33.
    • (2004) Curr Drug Targets Inflamm Allergy , vol.3 , pp. 19-33
    • Poff, C.D.1    Balazy, M.2
  • 18
    • 0026624938 scopus 로고
    • Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase
    • Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M. I., et al., Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther 1992, 26, 1143-1146.
    • (1992) J Pharmacol Exp Ther , vol.26 , pp. 1143-1146
    • Safayhi, H.1    Mack, T.2    Sabieraj, J.3    Anazodo, M.I.4
  • 19
    • 0030070162 scopus 로고    scopus 로고
    • Acetyl-11-keto-beta-boswellic acid (AKBA): structure requirements for binding and 5-lipoxygenase inhibitory activity
    • Sailer, E. R., Subramanian, L. R., Rall, B., Hoernlein, R. F., et al., Acetyl-11-keto-beta-boswellic acid (AKBA): structure requirements for binding and 5-lipoxygenase inhibitory activity. Br J Pharmacol 1996, 117, 615-618.
    • (1996) Br J Pharmacol , vol.117 , pp. 615-618
    • Sailer, E.R.1    Subramanian, L.R.2    Rall, B.3    Hoernlein, R.F.4
  • 20
    • 0031672111 scopus 로고    scopus 로고
    • Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling
    • Sailer, E. R., Schweizer, S., Boden, S. E., Ammon, H. P. T., et al., Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur J Biochem 1998, 256, 364-368.
    • (1998) Eur J Biochem , vol.256 , pp. 364-368
    • Sailer, E.R.1    Schweizer, S.2    Boden, S.E.3    Ammon, H.P.T.4
  • 21
    • 0029035973 scopus 로고
    • Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid
    • Safayhi, H., Sailer, E. R., Ammon, H. P. T., Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. Mol Pharmacol 1995, 47, 1212-1216.
    • (1995) Mol Pharmacol , vol.47 , pp. 1212-1216
    • Safayhi, H.1    Sailer, E.R.2    Ammon, H.P.T.3
  • 22
    • 20144389476 scopus 로고    scopus 로고
    • Human genome screen to identify the genetic basis of the anti-inflammatory effects of Boswellia in microvascular endothelial cells
    • Roy, S., Khanna, S., Shah, H., Rink, C., et al., Human genome screen to identify the genetic basis of the anti-inflammatory effects of Boswellia in microvascular endothelial cells. DNA Cell Biol 2005, 24(4), 244-255.
    • (2005) DNA Cell Biol , vol.24 , Issue.4 , pp. 244-255
    • Roy, S.1    Khanna, S.2    Shah, H.3    Rink, C.4
  • 23
    • 33646698430 scopus 로고    scopus 로고
    • Regulation of vascular response to inflammation: inducible matrix metalloprotenase-3 expression in human microvascular endothelial cells is sensitive to anti-inflammatory Boswellia.
    • Roy, S., Khanna, S., Krishnaraju, A.V., Subbaraju, G. V., et al., Regulation of vascular response to inflammation: inducible matrix metalloprotenase-3 expression in human microvascular endothelial cells is sensitive to anti-inflammatory Boswellia. Antioxid Redox Signal 2006, 8 (3&4), 653-660.
    • (2006) Antioxid Redox Signal , vol.8 , Issue.3-4 , pp. 653-660
    • Roy, S.1    Khanna, S.2    Krishnaraju, A.V.3    Subbaraju, G.V.4
  • 24
    • 33646384973 scopus 로고    scopus 로고
    • Safety and toxicological evaluation of a novel, standardized 3-acetyl-11-keto-ß-boswellic acid (AKBA)-enriched Boswellia serrata extract (5-Loxin)
    • Lalithakumari, K., Krishnaraju, A. V., Subbaraju, G. V., Yasmin, T., et al., Safety and toxicological evaluation of a novel, standardized 3-acetyl-11-keto-ß-boswellic acid (AKBA)-enriched Boswellia serrata extract (5-Loxin). Toxicol Mech Methods 2006, 16, 199-226.
    • (2006) Toxicol Mech Methods , vol.16 , pp. 199-226
    • Lalithakumari, K.1    Krishnaraju, A.V.2    Subbaraju, G.V.3    Yasmin, T.4
  • 25
    • 48849107660 scopus 로고    scopus 로고
    • Double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin R for treatment of osteoarthritis of the knee
    • Sengupta, K., Alluri, K. V., Satish, A. R., Mishra, S., et al., Double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin R for treatment of osteoarthritis of the knee. Arthritis Res Ther 2008, 10(4), R85-R96.
    • (2008) Arthritis Res Ther , vol.10 , Issue.4
    • Sengupta, K.1    Alluri, K.V.2    Satish, A.R.3    Mishra, S.4
  • 26
    • 0024013080 scopus 로고
    • Tumor necrosis factor: A plurifunctional mediator of acute inflammation.
    • Warren, J. S., Ward, P. A., Johnson, K. J., Tumor necrosis factor: A plurifunctional mediator of acute inflammation. Modern Pathol 1988, 1, 242-247
    • (1988) Modern Pathol , vol.1 , pp. 242-247
    • Warren, J.S.1    Ward, P.A.2    Johnson, K.J.3
  • 27
    • 0027488676 scopus 로고
    • Role of tumor necrosis factor-alpha in disease states and inflammation
    • Strieter, R. M., Kunkel, S. L., Bone, R. C., Role of tumor necrosis factor-alpha in disease states and inflammation. Crit Care Med 1993, 21, S447-S463.
    • (1993) Crit Care Med , vol.21
    • Strieter, R.M.1    Kunkel, S.L.2    Bone, R.C.3
  • 28
    • 0141456205 scopus 로고    scopus 로고
    • Regulation of inflammation
    • Sullivan, K. E., Regulation of inflammation. Immunol Res 2003, 27, 529-538.
    • (2003) Immunol Res , vol.27 , pp. 529-538
    • Sullivan, K.E.1
  • 29
    • 84877261134 scopus 로고    scopus 로고
    • Endothelial activation: Untracellular signaling pathways
    • Pober, J. S., Endothelial activation: Untracellular signaling pathways. Arthritis Res 2002, 4(3), S109-S116.
    • (2002) Arthritis Res , vol.4 , Issue.3
    • Pober, J.S.1
  • 30
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • Li, C., Wong, W. H., Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proc Natl Acad Sci 2001, 98, 31-36.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.H.2
  • 31
    • 0028231065 scopus 로고
    • Adhesion molecules and inflammatory injury
    • Albelda, S. M., Smith, C. W., Ward, P. A., Adhesion molecules and inflammatory injury. FASEB 1994, 8, 504-512.
    • (1994) FASEB , vol.8 , pp. 504-512
    • Albelda, S.M.1    Smith, C.W.2    Ward, P.A.3
  • 33
    • 0031656460 scopus 로고    scopus 로고
    • Matrix metalloprotenases: Structures, evolution, and diversification
    • Massova, I., Kotra, L. P., Fridman, R., Mobashery, S., Matrix metalloprotenases: Structures, evolution, and diversification. FASEB Journal 1998, 12, 1075-1095.
    • (1998) FASEB Journal , vol.12 , pp. 1075-1095
    • Massova, I.1    Kotra, L.P.2    Fridman, R.3    Mobashery, S.4
  • 34
    • 1942423221 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases (MMPs) and their inhibitors in venous leg ulcer healing
    • Herouy, Y., The role of matrix metalloproteinases (MMPs) and their inhibitors in venous leg ulcer healing. Phlebolymphology 2004, 44, 231-243.
    • (2004) Phlebolymphology , vol.44 , pp. 231-243
    • Herouy, Y.1
  • 35
    • 84886545249 scopus 로고    scopus 로고
    • 30% 3-O-acetyl-11-keto-ß-boswellic acid inhibits phorbol-myristate acetate stimulated matrix metalloproteinase-3 in A2058 human melanoma cells. Study no. LI/CMB/MMP-3/02/08. Submitted to the archival files, Laila Impex R&D Center, 2008.
    • Sengupta, K., Tummala, T., Golakoti, T., 30% 3-O-acetyl-11-keto-ß-boswellic acid inhibits phorbol-myristate acetate stimulated matrix metalloproteinase-3 in A2058 human melanoma cells. Study no. LI/CMB/MMP-3/02/08. Submitted to the archival files, Laila Impex R&D Center, 2008.
    • Sengupta, K.1    Tummala, T.2    Golakoti, T.3
  • 36
    • 84886488223 scopus 로고    scopus 로고
    • Bacterial reverse mutation test with 5-Loxin. Study No. 4477/05, Toxicology Department, Advinus Therapeutics Private Limited, Post Box No. 5813, Plot Nos 21 & 22
    • Peenya Industrial Area, Phase II, Bangalore, India 560 058
    • Indrani, B. K., Bacterial reverse mutation test with 5-Loxin. Study No. 4477/05, Toxicology Department, Advinus Therapeutics Private Limited, Post Box No. 5813, Plot Nos 21 & 22, Peenya Industrial Area, Phase II, Bangalore, India 560 058, 2006.
    • (2006)
    • Indrani, B.K.1
  • 37
    • 84886555705 scopus 로고    scopus 로고
    • Micronucleus assay in mice 5-Loxin. Study numbers MN00075 and CA00094, Center of Toxicology and Preclinical Sciences
    • Development Center for Biotechnology, 101, Lane 169, Kangning St, Xizhi City, Taipei County 221, Taiwan
    • Chang, J-T., Micronucleus assay in mice 5-Loxin. Study numbers MN00075 and CA00094, Center of Toxicology and Preclinical Sciences, Development Center for Biotechnology, 101, Lane 169, Kangning St, Xizhi City, Taipei County 221, Taiwan, 2007.
    • (2007)
    • Chang, J.-T.1
  • 38
    • 26844431788 scopus 로고    scopus 로고
    • Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis
    • Takahashi, M., Naito, K., Abe, M., Sawada, T., et al., Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis. Arthritis Res Ther 2004, 6(3), R208-R212.
    • (2004) Arthritis Res Ther , vol.6 , Issue.3
    • Takahashi, M.1    Naito, K.2    Abe, M.3    Sawada, T.4
  • 39
    • 0024268463 scopus 로고
    • Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to anti-rheumatic drug therapy in patients with osteoarthritis of the hip or knee
    • Bellamy, N., Buchnan, W. W., Goldsmith, C. H., Campbell, J., et al., Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to anti-rheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988, 15, 1833-1840.
    • (1988) J Rheumatol , vol.15 , pp. 1833-1840
    • Bellamy, N.1    Buchnan, W.W.2    Goldsmith, C.H.3    Campbell, J.4
  • 40
    • 0023477362 scopus 로고
    • Indexes of severity for osteoarthritis of the hip and knee validation-value in comparison with other assessment tests
    • Lequesne, M. G., Mery, C., Samson, M., Gerard, P., Indexes of severity for osteoarthritis of the hip and knee validation-value in comparison with other assessment tests. Scand J Rheumatol 1987, 65, 85-89.
    • (1987) Scand J Rheumatol , vol.65 , pp. 85-89
    • Lequesne, M.G.1    Mery, C.2    Samson, M.3    Gerard, P.4


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