Biotransformation of 17α-ethynyl substituted steroidal drugs with microbial and plant cell cultures: A review

Steroids

Volumn 78, Issue 14, 2013, Pages 1312-1324

  Shah, Syed Adnan Ali ^a   Sultan, Sadia ^a   Hassan, Normahanim Binti ^a   Muhammad, Fauzia Khadija Binti ^a   Faridz, Muhammad Afifi Bin Mohd ^a   Hussain, Fatimah Bebe M ^a   Hussain, Munawar ^b   Adnan, Humera Syed ^c  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b DHA SUFFA UNIVERSITY   (Pakistan)

^c UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

17 Ethynyl substituted steroidal drugs; Cell suspension cultures; Microbial strains; Microbial transformation

Indexed keywords

10BETA HYDROXY 4DELTA TIBOLONE; 11ALPHA,15BETA DIHYDROXY 5DELTA TIBOLONE; 13 ETHYL 10BETA,17BETA DIHYDROXY 18,19 DINOR 17ALPHA PREGN 4 EN 20 YN 3 ONE; 13 ETHYL 15ALPH,17BETA DIHYDROXY 18,19 DINOR 17ALPHA PREGN 4 EN 20 YN 3 ONE; 13 ETHYL 7BETA,17BETA DIHYDROXY 18,19 DINOR 17ALPHA PREGN 4 EN 20 YN 3 ONE; 13- ETHYL 11ALPHA,17BETA DIHYDROXY 18,19 DINOR 17ALPHA PREGN 4 EN 20 YN 3 ONE; 15ALPHA HYDROXY 4DELTA TIBOLONE; 15BETA HYDROXYTIBOLONE; 17ALPHA ETHYNYL 11ALPHA,17BETA DIHYDROXYANDROXYANDROST 4 EN 3 ONE; 17ALPHA ETHYNYL 17BETA HYDROXYANDROSTA 1,4 DIEN 3 ONE; 17ALPHA ETHYNYL 7BETA,17BETA DIHYDROXYANDROST 4 EN 3 ONE; 17BETA HYDROXY 2(HYDROXYMETHYL) 17ALPHA PREGN 1,4 DIEN 20 YN 3 ONE; 17BETA HYDROXY 2(HYDROXYMETHYL) 17ALPHA PREGN 4 EN 20 YN 3 ONE; 19 NOR 17ALPHA PREGN 4 EN 20 YN 3 ONE 6BETA,17BETA DIOL; 19 NOR 17ALPHA PREGN 4 EN 20 YN 3BETA,6,17BETA TRIOL; 19 NOR 17ALPHA PREGNA 1,3,5(10)TRIEN 20 YNE 3,17BETA DIOL 6BETA METHOXY; 19 NOR 17ALPHA PREGNA 1,3,5(10)TRIEN 20 YNE 3,6BETA,17BETA TRIOL; 19 NOR 17ALPHA PREGNA 1,3,5(10)TRIEN 20 YNE 3,7ALPHA,17BETA TRIOL; 19 NOR 17ALPHA PREGNA 4(10)DIOXO E2EN 17 HYDROXY 1,3 DION; 3ALPHA HYDROXY 5DELTA TIBOLONE; 3ALPHA,11ALPHA DIHYDROXY 4DELTA TIBOLONE; 3ALPHA,6APHA DIHYDROXY 4DELTA TIBOLONE; 4DELTA TIBOLONE; 6ALPHA HYDROXY DELTA4 TIBOLONE; 6BETA HYDROXYTIBOLONE; 6BETA METHOXY 4DELTA TIBOLONE; 6BETA,12BETA DIHYDROXYMESTRANOL; DRUG METABOLITE; STEROID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ASPERGILLUS NIGER; ASPERGILLUS OCHRACEUS; AZADIRACHTA INDICA; BASIL; CALLUS CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CUNNINGHAMELLA BLAKESLEEANA; CUNNINGHAMELLA ECHINULATA; CUNNINGHAMELLA ELEGANS; CURVULARIA LUNATA; DRUG DECOMPOSITION; DRUG STRUCTURE; DRUG TRANSFORMATION; FUNGAL CELL CULTURE; FUSARIUM; GIBBERELLA FUJIKUROI; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; OCIMUM TENUIFLORUM; PLANT CELL CULTURE; PLEUROTUS OSTREATUS; REVIEW; RHIZOPUS ARRHIZUS; RHIZOPUS STOLONIFER;

APIS; BACTERIA (MICROORGANISMS); FUNGI;

17Α-ETHYNYL SUBSTITUTED STEROIDAL DRUGS; CELL SUSPENSION CULTURES; MICROBIAL STRAINS; MICROBIAL TRANSFORMATION;

BACTERIA; BIOTRANSFORMATION; CELL CULTURE TECHNIQUES; DRUG DISCOVERY; ESTRENES; ETHINYL ESTRADIOL; FUNGI; HUMANS; NORPREGNENES; PLANT CELLS; PREGNENES; STEREOISOMERISM;

EID: 84886550795     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2013.10.001     Document Type: Review

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