Enhanced drug delivery via hyperthermal membrane disruption using targeted gold nanoparticles with PEGylated Protein-G as a cofactor

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 8, 2013, Pages 1214-1222

  Sun, Xinghua ^a   Zhang, Guandong ^a   Keynton, Robert S ^a   O'Toole, Martin G ^a   Patel, Dhruvinkumar ^a   Gobin, Andre M ^a  

^a University of Louisville   (United States)

Author keywords

Cellular uptake and membrane disruption; Gold nanoparticle; Hyperthermia anticancer drug therapy; PEGylated Protein G; Targeted cancer therapy

Indexed keywords

CELLULAR SENSITIVITY; CHEMOTHERAPEUTIC AGENTS; GOLD NANOPARTICLES; GOLD NANOPARTICLES (GNPS); MEMBRANE DISRUPTION; PEGYLATED; PHOTOTHERMAL CANCER THERAPY; TARGETED CANCER THERAPY;

CELL DEATH; CELL MEMBRANES; DISEASES; DRUG DELIVERY; GOLD; INFRARED DEVICES; METAL NANOPARTICLES; ONCOLOGY; OPTIMIZATION; RECOMBINANT PROTEINS;

HYPERTHERMIA THERAPY;

ANTINEOPLASTIC AGENT; GOLD NANOPARTICLE; IMMUNOGLOBULIN G; PEGYLATED RECOMBINANT PROTEIN G; PROTEIN G; UNCLASSIFIED DRUG;

ARTICLE; CANCER THERAPY; CELL DAMAGE; CELL DEATH; CELL KILLING; CELL MEMBRANE PERMEABILITY; CONJUGATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HYPERTHERMIA; IN VITRO STUDY; LASER SURGERY; MEMBRANE DAMAGE;

CELLULAR UPTAKE AND MEMBRANE DISRUPTION; GOLD NANOPARTICLE; HYPERTHERMIA-ANTICANCER DRUG THERAPY; PEGYLATED PROTEIN-G; TARGETED CANCER THERAPY;

ANTIBODIES, IMMOBILIZED; ANTINEOPLASTIC AGENTS; BACTERIAL PROTEINS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; GOLD; HUMANS; HYPERTHERMIA, INDUCED; IMMUNOGLOBULIN G; LASER THERAPY; NANOPARTICLES; POLYETHYLENE GLYCOLS; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS;

EID: 84886443453     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.04.002     Document Type: Article

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