HIV infection is associated with reduced pulmonary diffusing capacity

Journal of Acquired Immune Deficiency Syndromes

Volumn 64, Issue 3, 2013, Pages 271-278

  Crothers, Kristina ^a   McGinnis, Kathleen ^b   Kleerup, Eric ^c   Wongtrakool, Cherry ^d   Hoo, Guy S ^e   Kim, Joon ^f   Sharafkhaneh, Amir ^g   Huang, Laurence ^h   Luo, Zhaoyu ⁱ   Thompson, Bruce ⁱ   Diaz, Philip ^j   Kirk, Gregory D ^k   Rom, William ^l   Detels, Roger ^c   Kingsley, Lawrence ^m   Morris, Alison ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g BAYLOR COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ Clinical Trials and Survey Corporation ^*  (United States)

^j THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^k JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

more..

Author keywords

COPD; DLCO; FEV1; gas exchange; HIV AIDS; pulmonary function

Indexed keywords

CARBON MONOXIDE;

ADULT; AIRFLOW; ARTICLE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; COUGHING; DISEASE ASSOCIATION; DYSPNEA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LUNG; LUNG DISEASE; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK FACTOR; SPIROMETRY; AGE; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; COUGH; CROSS-SECTIONAL STUDY; LONGITUDINAL STUDY; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PREVALENCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SEVERITY OF ILLNESS INDEX; SMOKING; UNITED STATES; VETERAN; VIROLOGY; VIRUS LOAD;

AGE FACTORS; CD4 LYMPHOCYTE COUNT; COUGH; CROSS-SECTIONAL STUDIES; DYSPNEA; HIV INFECTIONS; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PREVALENCE; PULMONARY DIFFUSING CAPACITY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUESTIONNAIRES; RESPIRATORY FUNCTION TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SMOKING; UNITED STATES; VETERANS; VIRAL LOAD;

EID: 84886421240     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3182a9215a     Document Type: Article

References (56)

1. Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338: 853-860.
2. Mocroft A, Brettle R, Kirk O, et al. Changes in the cause of death among HIV positive subjects across Europe: results from the EuroSIDA study. AIDS. 2002;16:1663-1671.
3. Crum NF, Riffenburgh RH, Wegner S, et al. Comparisons of causes of death and mortality rates among HIV-infected persons: analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras. J Acquir Immune Defic Syndr. 2006;41:194-200.
4. Braithwaite RS, Justice AC, Chang CC, et al. Estimating the proportion of patients infected with HIV who will die of comorbid diseases. Am J Med. 2005;118:890-898.
5. Lau B, Gange SJ, Moore RD. Risk of non-AIDS-related mortality may exceed risk of AIDS-related mortality among individuals enrolling into care with CD4+ counts greater than 200 cells/mm3. J Acquir Immune Defic Syndr. 2007;44:179-187.
6. Marin B, Thiebaut R, Bucher HC, et al. Non-AIDS-defining deaths and immunodeficiency in the era of combination antiretroviral therapy. AIDS. 2009;23:1743-1753.
7. Murray JF, Mills J. Pulmonary infectious complications of human immunodeficiency virus infection. Part II. Am Rev Respir Dis. 1990; 141:1582-1598.
8. Murray JF, Mills J. Pulmonary infectious complications of human immunodeficiency virus infection. Part I. Am Rev Respir Dis. 1990;141(5 pt 1): 1356-1372.
9. Wallace JM, Hansen NI, Lavange L, et al. Respiratory disease trends in the Pulmonary Complications of HIV Infection Study cohort. Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med. 1997;155:72-80.
10. Crothers K, Huang L, Goulet JL, et al. HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. Am J Respir Crit Care Med. 2011;183:388-395.
11. Kirk GD, Merlo C, O' Driscoll P, et al. HIV infection is associated with an increased risk for lung cancer, independent of smoking. Clin Infect Dis. 2007;45:103-110.
12. Drummond MB, Kirk GD, Astemborski J, et al. Association between obstructive lung disease and markers of HIV infection in a high-risk cohort. Thorax. 2012;67:309-314.
13. Almodovar S, Hsue PY, Morelli J, et al. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. Proc Am Thorac Soc. 2011;8:308-312.
14. Gingo MR, George MP, Kessinger CJ, et al. Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era. Am J Respir Crit Care Med. 2010;182:790-796.
15. Madeddu G, Fois AG, Calia GM, et al. Chronic obstructive pulmonary disease: an emerging comorbidity in HIV-infected patients in the HAART era? Infection. 2013;41(2):347-53.
16. Diaz PT, King MA, Pacht ER, et al. Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers. Ann Intern Med. 2000;132:369-372.
17. Mehta NJ, Khan IA, Mehta RN, et al. HIV-Related pulmonary hypertension: analytic review of 131 cases. Chest. 2000;118:1133-1141.
18. Sigel K, Wisnivesky J, Gordon K, et al. HIV as an independent risk factor for incident lung cancer. AIDS. 2012;26:1017-1025.
19. Diaz PT, Wewers MD, Pacht E, et al. Respiratory symptoms among HIV-seropositive individuals. Chest. 2003;123:1977-1982.
20. George MP, Kannass M, Huang L, et al. Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era. PLoS One. 2009;4:e6328.
21. Mitchell DM, Fleming J, Pinching AJ, et al. Pulmonary function in human immunodeficiency virus infection. A prospective 18-month study of serial lung function in 474 patients. Am Rev Respir Dis. 1992;146:745-751.
22. Rosen MJ, Lou Y, Kvale PA, et al. Pulmonary function tests in HIVinfected patients without AIDS. Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med. 1995;152:738-745.
23. Crothers K, Thompson BW, Burkhardt K, et al. HIV-associated lung infections and complications in the era of combination antiretroviral therapy. Proc Am Thorac Soc. 2011;8:275-281.
24. Crothers K, Kleerup E, Wongtrakool C, et al. HIV infection is associated with impaired pulmonary diffusing capacity. Paper presented at: 19th Conference on Retroviruses and Opportunistic Infections; March 7, 2012; Seattle, WA.
25. Detels R, Jacobson L, Margolick J, et al. The multicenter AIDS Cohort Study, 1983 to.. Public Health. 2012;126:196-198.
26. Justice AC, Dombrowski E, Conigliaro J, et al. Veterans Aging Cohort Study (VACS): overview and description. Med Care. 2006;44(8 suppl 2): S13-S24.
27. Kaslow RA, Ostrow DG, Detels R, et al. The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants. Am J Epidemiol. 1987;126:310-318.
28. Macintyre N, Crapo RO, Viegi G, et al. Standardisation of the singlebreath determination of carbon monoxide uptake in the lung. Eur Respir J. 2005;26:720-735.
29. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26:319-338.
30. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. [Updated 2013]. 2013. Available at: http://www.goldcopd.org/.
31. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med. 1999;159:179-187.
32. Neas LM, Schwartz J. The determinants of pulmonary diffusing capacity in a national sample of U.S. adults. Am J Respir Crit Care Med. 1996; 153:656-664.
33. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J. 2005;26:948-968.
34. Ferris BG. Epidemiology Standardization Project (American Thoracic Society). Am Rev Respir Dis. 1978;118(6 pt 2):1-120.
35. Bestall JC, Paul EA, Garrod R, et al. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999;54:581-586.
36. Fletcher CM, Elmes PC, Fairbairn AS, et al. The significance of respiratory symptoms and the diagnosis of chronic bronchitis in a working population. Br Med J. 1959;5147:257-266.
37. Mannino DM, Buist AS, Petty TL, et al. Lung function and mortality in the United States: data from the First National Health and Nutrition Examination Survey follow up study. Thorax. 2003;58:388-393.
38. Neas LM, Schwartz J. Pulmonary function levels as predictors of mortality in a national sample of US adults. Am J Epidemiol. 1998;147:1011-1018.
39. Ward H, Cooper B, Miller MR. Validation of lung function prediction equations from patient survival data. Eur Respir J. 2012;39:1181-1187.
40. Ferguson MK, Dignam JJ, Siddique J, et al. Diffusing capacity predicts long-term survival after lung resection for cancer. Eur J Cardiothorac Surg. 2012;41:e81-e86.
41. Chandra S, Shah SJ, Thenappan T, et al. Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension. J Heart Lung Transplant. 2010;29:181-187.
42. Ferguson MK, Gaissert HA, Grab JD, et al. Pulmonary complications after lung resection in the absence of chronic obstructive pulmonary disease: the predictive role of diffusing capacity. J Thorac Cardiovasc Surg. 2009;138:1297-1302.
43. Oursler KK, Goulet JL, Crystal S, et al. Association of age and comorbidity with physical function in HIV-infected and uninfected patients: results from the Veterans Aging Cohort Study. AIDS Patient Care STDS. 2011;25:13-20.
44. Oursler KK, Sorkin JD, Smith BA, et al. Reduced aerobic capacity and physical functioning in older HIV-infected men. AIDS Res Hum Retroviruses. 2006;22:1113-1121.
45. Diaz PT, King MA, Pacht ER, et al. The pathophysiology of pulmonary diffusion impairment in human immunodeficiency virus infection. Am J Respir Crit Care Med. 1999;160:272-277.
46. Diaz PT, Clanton TL, Pacht ER. Emphysema-like pulmonary disease associated with human immunodeficiency virus infection. Ann Intern Med. 1992;116:124-128.
47. Barnett CF, Hsue PY, Machado RF. Pulmonary hypertension: an increasingly recognized complication of hereditary hemolytic anemias and HIV infection. JAMA. 2008;299:324-331.
48. Butt AA, Chang CC, Kuller L, et al. Risk of heart failure with human immunodeficiency virus in the absence of prior diagnosis of coronary heart disease. Arch Intern Med. 2011;171:737-743.
49. Washko GR, Hunninghake GM, Fernandez IE, et al. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med. 2011;364:897-906.
50. Armah KA, McGinnis K, Baker J, et al. HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. Clin Infect Dis. 2012;55:126-136.
51. Kuller LH, Tracy R, Belloso W, et al. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med. 2008;5:e203.
52. Twigg HL, Soliman DM, Day RB, et al. Lymphocytic alveolitis, bronchoalveolar lavage viral load, and outcome in human immunodeficiency virus infection. Am J Respir Crit Care Med. 1999;159(5 pt 1):1439-1444.
53. Kaner RJ, Santiago F, Crystal RG. Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema. J Leukoc Biol. 2009;86:913-922.
54. Stansell JD, Osmond DH, Charlebois E, et al. Predictors of Pneumocystis carinii pneumonia in HIV-infected persons. Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med. 1997;155:60-66.
55. Crothers K, Butt AA, Gibert CL, et al. Increased COPD among HIVpositive compared to HIV-negative veterans. Chest. 2006;130:1326-1333.
56. Miller MR, Crapo R, Hankinson J, et al. General considerations for lung function testing. Eur Respir J. 2005;26:153-161.