Frequency of sexual activity and cardiovascular risk in subjects with erectile dysfunction: Cross-sectional and longitudinal analyses

Andrology

Volumn 1, Issue 6, 2013, Pages 864-871

  Corona, G ^a,e   Rastrelli, G ^a   Monami, M ^c   Maseroli, E ^a   Jannini, E A ^d   Balercia, G ^b   Sforza, A ^e   Forti, G ^a   Mannucci, E ^f   Maggi, M ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UNIVERSITY OF L'AQUILA   (Italy)

^e BELLARIA HOSPITAL   (Italy)

^f CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Erectile dysfunction; Hormones; Testosterone

Indexed keywords

TESTOSTERONE;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CROSS-SECTIONAL STUDY; DELAYED EJACULATION; DEPRESSION; EJACULATION; ERECTILE DYSFUNCTION; FOLLOW UP; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTPATIENT DEPARTMENT; PREMATURE EJACULATION; PREMATURITY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE;

ERECTILE DYSFUNCTION; HORMONES; TESTOSTERONE;

ADULT; AGED; CARDIOVASCULAR DISEASES; DEPRESSION; ERECTILE DYSFUNCTION; HUMANS; ITALY; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SEXUAL BEHAVIOR;

EID: 84886415609     PISSN: 20472919     EISSN: 20472927     Source Type: Journal    
DOI: 10.1111/j.2047-2927.2013.00139.x     Document Type: Article

References (49)

1. Bandini E, Fisher AD, Corona G, Ricca V, Monami M, Boddi V et al. (2010) Severe depressive symptoms and cardiovascular risk in subjects with erectile dysfunction. J Sex Med 7, 3477-3486.
2. Blanker MH, Bohnen AM, Groeneveld FP, Bernsen RM, Prins A, Thomas S et al. (2001) Correlates for erectile and ejaculatory dysfunction in older Dutch men: a community-based study. J Am Geriatr Soc 49, 436-442.
3. Boddi V, Corona G, Fisher AD, Mannucci E, Ricca V, Sforza A et al. (2012) "It takes two to tango": the relational domain in a cohort of subjects with erectile dysfunction (ED). J Sex Med 9, 3126-3136.
4. Bohlen JG, Held JP, Sanderson O & Patterson RP. (1984) Heart rate, rate pressure product and oxygen up take in four sexual activities. Am Heart J 92, 274-277.
5. Carosa E, Benvenga S, Trimarchi F, Lenzi A, Pepe M, Simonelli C et al. (2002) Sexual inactivity results in reversible reduction of LH bioavailability. Int J Impot Res 14, 93-99.
6. Corona G, Petrone L, Mannucci E, Magini A, Lotti F, Ricca V et al. (2006a) Assessment of the relational factor in male patients consulting for sexual dysfunction: the concept of couple sexual dysfunction. J Androl 27, 795-801.
7. Corona G, Mannucci E, Petrone L, Fisher AD, Balercia G, De Scisciolo G et al. (2006b) Psychobiological correlates of delayed ejaculation in male patients with sexual dysfunctions. J Androl 27, 453-458.
8. Corona G, Mannucci E, Petrone L, Ricca V, Balercia G, Giommi R et al. (2006c) Psycho-biological correlates of free-floating anxiety symptoms in male patients with sexual dysfunctions. J Androl 27, 86-93.
9. Corona G, Forti G & Maggi M. (2008a) Why can patients with erectile dysfunction be considered lucky? The association with testosterone deficiency and metabolic syndrome. Aging Male 11, 193-199.
10. Corona G, Fagioli G, Mannucci E, Romeo A, Rossi M, Lotti F et al. (2008b) Penile doppler ultrasound in patients with erectile dysfunction (ED): role of peak systolic velocity measured in the flaccid state in predicting arteriogenic ED and silent coronary artery disease. J Sex Med 5, 2623-2634.
11. Corona G, Mannucci E, Ricca V, Lotti F, Boddi V, Bandini E et al. (2009) The age-related decline of testosterone is associated with different specific symptoms and signs in patients with sexual dysfunction. Int J Androl 32, 720-728.
12. Corona G, Monami M, Boddi V, Cameron-Smith M, Lotti F, de Vita G et al. (2010a) Male sexuality and cardiovascular risk. A cohort study in patients with erectile dysfunction. J Sex Med 7, 1918-1927.
13. Corona G, Lee DM, Forti G, O'Connor DB, Maggi M, O'Neill TW et al. (2010b) Age-related changes in general and sexual health in middle-aged and older men: results from the European Male Study (EMAS). J Sex Med 7, 362-380.
14. Corona G, Monami M, Boddi V, Cameron-Smith M, Fisher AD, de Vita G et al. (2010c) Low testosterone is associated with an increased risk of MACE lethality in subjects with erectile dysfunction. J Sex Med 7(4 Pt 1), 1557-1564.
15. Corona G, Bandini E, Fisher AD, Maseroli E, Boddi V, Sforza A et al. (2010d) Psychobiological correlates of women's sexual interest as perceived by patients with erectile dysfunction. J Sex Med 7, 2174-2183.
16. Corona G, Jannini EA, Lotti F, Boddi V, De Vita G, Forti G et al. (2011) Premature and delayed ejaculation: two ends of a single continuum influenced by hormonal milieu. Int J Androl 34, 41-48.
17. Corona G, Ricca V, Bandini E, Rastrelli G, Casale H, Jannini EA et al. (2012a) SIEDY scale 3, a new instrument to detect psychological component in subjects with erectile dysfunction. J Sex Med 9, 2017-2026.
18. Corona G, Jannini EA, Vignozzi L, Rastrelli G & Maggi M. (2012b) The hormonal control of ejaculation. Nat Rev Urol 9, 508-519.
19. Corona G, Rastrelli G, Ricca V, Jannini EA, Vignozzi L, Monami M et al. (2013) Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction. J Sex Med 10, 1074-1089.
20. Crown S & Crisp AH. (1966) A short clinical diagnostic self-rating scale for psychoneurotic patients. The Middlesex Hospital Questionnaire (M.H.Q.). Br J Psychiatry 112, 917-923.
21. Dahabreh IJ & Paulus JK. (2011) Association of episodic physical and sexual activity with triggering of acute cardiac events: systematic review and meta-analysis. JAMA 305, 1225-1233.
22. Drovy Y. (2002) Sexual activity and cardiovascular risk. Eur Heart J 2002(Suppl. H), H13-H18.
23. Franco OH, de Laet C, Peeters A, Jonker J, Mackenbach J & Nusselder W. (2005) Effects of physical activity on life expectancy with cardiovascular disease. Arch Intern Med 165, 2355-2360.
24. Gazzaruso C, Solerte SB, Pujia A, Coppola A, Vezzoli M, Salvucci F et al. (2008) Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: a potential protective role for statins and 5-phosphodiesterase inhibitors. J Am Coll Cardiol 51, 2040-2044.
25. Guo W, Liao C, Zou Y, Li F, Li T, Zhou Q et al. (2010) Erectile dysfunction and risk of clinical cardiovascular events: a meta-analysis of seven cohort studies. J Sex Med 7, 2805-2816.
26. Hall SA, Shackelton R, Rosen RC & Araujo AB. (2010) Sexual activity, erectile dysfunction and incident cardiovascular events. Am J Cardiol 105, 192-197.
27. Hatzichristou D, Rosen R, Derogatis L, Low WY, Meuleman E, Sadvsky R et al. (2010) Clinical evaluation and symptom scales in men and women with sexual dysfunction. In: Sexual Medicine: Sexual Dysfunctions in Men and Women. The 3rd International Consultation on Sexual Medicine (eds F Montorsi, R Basson, G Adaikan, E Becher, A Clayton, F Giuliano, S Khoury & I Sharlip ), pp. 229-280. Health Publication Ltd, Paris.
28. Inman BA, Sauver JL, Jacobson DJ, McGree ME, Nehra A, Lieber MM et al. (2009) A population-based, longitudinal study of erectile dysfunction and future coronary artery disease. Mayo Clin Proc 84, 108-113.
29. Jannini EA, Screponi E, Carosa E, Pepe M, Lo Giudice F, Trimarchi F et al. (1999) Lack of sexual activity from erectile dysfunction is associated with a reversible reduction in serum testosterone. Int J Androl 22, 385-392.
30. Jannini EA, Fisher WA, Bitzer J & McMahon CG. (2009) Is sex just fun? How sexual activity improves health. J Sex Med 6, 2640-2648.
31. Libby P. (2005) The forgotten majority: unfinished business in cardiovascular risk reduction. J Am Coll Cardiol 46, 1225-1228.
32. Lindau ST & Gavrilova N. (2010) Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing. BMJ 340, c810.
33. Lindau ST, Schumm LP, Laumann EO, Levinson W, O'Muircheartaigh CA & Waite LJ. (2007) A study of sexuality and health among older adults in the United States. N Engl J Med 357, 762-774.
34. Maggi M & Corona G. (2011) Love protects lover's life. J Sex Med 8, 931-935.
35. McGregor JC, Kim PW, Perencevich EN, Bradham DD, Furuno JP, Kaye KS et al. (2005) Utility of the Chronic Disease Score and Charlson Comorbidity Index as comorbidity measures for use in epidemiologic studies of antibioticresistant organisms. Am J Epidemiol 161, 483-493.
36. Murray CJ & Lopez AD. (1997) Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504.
37. Nehra A, Jackson G, Miner M, Billups KL, Burnett AL, Buvat J et al. (2012) The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc 87, 766-778.
38. NIH Consensus Development Panel on Impotence (1999) NHI Consensus Conference on Impotence. JAMA 279, 83-90.
39. O'Connor DB, Corona G, Forti G, Tajar A, Lee DM, Finn JD et al. (2008) Assessment of sexual health in aging men in Europe: development and validation of the European Male Ageing Study sexual function questionnaire. J Sex Med 5, 1374-1385.
40. Palmore EB. (1982) Predictor of longevity difference: a 25 year follow-up. Gerontologist 22, 513-518.
41. Pastuszak AW, Badhiwala N, Lipshultz LI & Khera M. (2013) Depression is correlated with the psychological and physical aspects of sexual dysfunction in men. Int J Impot Res 25, 194-199.
42. Persson G. (1981) Five-year mortality in a 70-year-old urban population in relation to psychiatric diagnosis, personality, sexuality and early parental death. Acta Psychiatr Scand 64, 244-253.
43. Petrone L, Mannucci E, Corona G, Bartolini M, Forti G, Giommi R et al. (2003) Structured interview on erectile dysfunction (SIEDY): a new, multidimensional instrument for quantification of pathogenetic issues on erectile dysfunction. Int J Impot Res 15, 210-220.
44. Schouten BW, Bohnen AM, Bosch JL, Bernsen RM, Deckers JW, Dohle GR et al. (2008) Erectile dysfunction prospectively associated with cardiovascular disease in the Dutch general population: results from the Krimpen study. Int J Impot Res 20, 92-99.
45. Seftel AD. (2006) Diagnosis of erectile dysfunction. In: Standard Practice in Sexual Medicine (eds H Porst & J Buvat ), p. 67. Blackwell Publishing, Malden, MA.
46. Thompson IM, Tangen CM, Goodman PJ, Probstfield JL, Moinpour CM & Coltman CA. (2005) Erectile dysfunction and subsequent cardiovascular disease. JAMA 294, 2996-3002.
47. Thompson PD, Franklin BA, Balady GJ, Blair SN, Corrado D, Estes NA3rd et al.; American Heart Association Council on Nutrition, Physical Activity, and Metabolism; American Heart Association Council on Clinical Cardiology; American College of Sports Medicine (2007). Exercise and acute cardiovascular events: placing the risks into perspective: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism and the Council on Clinical Cardiology. Circulation 115, 2358-2368.
48. Van der Kooy K, Van Hout H, Marwijk H, Marten H, Stehouwer C & Beekman A. (2007) Depression and the risk for cardiovascular diseases: systematic review and meta analysis. Int J Geriatr Psychiatry 22, 613-626.
49. Vignozzi L, Corona G, Petrone L, Filippi S, Morelli AM, Forti G et al. (2005) Testosterone and sexual activity. J Endocrinol Invest 28(3 Suppl.), 39-44.