Chemical composition, in vitro antimicrobial and antioxidant activities of the essential oils of Ocimum gratissimum, O. sanctum and their major constituents

Indian Journal of Pharmaceutical Sciences

Volumn 75, Issue 4, 2013, Pages 457-462

  Joshi, R ^a  

^a INDIAN COUNCIL OF MEDICAL RESEARCH   (India)

Author keywords

Antimicrobial activity; antioxidant activity; eugenol; GC MS; methyl eugenol; O. sanctum; Ocimum gratissimum

Indexed keywords

4 CARANONE; ALPHA CUBEBENE; ALPHA THUJENE; ANTIINFECTIVE AGENT; ANTIOXIDANT; BETA PINENE; BORNEOL; CAMPHENE; CARVACROL; CINEOLE; ESSENTIAL OIL; ESTRAGOLE; EUGENOL; GERMACRENE D; METHYL EUGENOL; MYRCENE; OCIMENE; PARA CYMENE; PINENE; SABINENE; SABINENE HYDRATE; SALICYLIC ACID METHYL ESTER; TERPINEN 4 OL; TERPINENE; TERPINEOL; TERPINOLENE; THYMOL; TRANS 4 CARANONE; TROLOX C; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CHEMICAL COMPOSITION; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DILUTION; DRUG SCREENING; ENTEROBACTER AEROGENES; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; IC 50; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MASS FRAGMENTOGRAPHY; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OCIMUM GRATISSIMUM; OCIMUM TENUIFLORUM; PENICILLIUM CHRYSOGENUM; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 84886414231     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.119834     Document Type: Article

References (28)

1. WHO, 2007. Available from: http://www.who.int/mediacentre/factsheets/ fs134/en/[Last accessed on 2013 May 28].
2. Baratta MT, Dorman HJ, Deans SG, Figueiredo AC, Barroso JG, Ruberto G. Antimicrobial and antioxidant properties of some commercial essential oils. Flavour Frag J 1998;13:235-44. (Pubitemid 28473109)
3. Geissman TA. Flavonoid compounds, tannins, lignins and related compounds. In: Florkin M, Stotz, editors. Pyrrole pigments, isoprenoid compounds and phenolic plant constituents. New York, USA: Elsevier Press; 1963. p. 265.
4. Cowan MM. Plant products as antimicrobial agents. Clin Microbiol Rev 1999;12:564-82. (Pubitemid 29484747)
5. Lu Y, Foo YL. Antioxidant activities of polyphenols from sage (Salvia officinalis). Food Chem 2001;75:197-202. (Pubitemid 32895704)
6. Erlund I, Alfthan G, Maenpaa J, Aro A. Tea and coronary heart disease: The flavonoid quercetin is more bioavailable from rutin in women than in men. Arch Intern Med 2001;161:1919-20. (Pubitemid 32762749)
7. Yang YC, Lu FH, Wu JS, Wu CH, Chang CJ. The protective effect of habitual tea consumption on hypertension. Arch Intern Med 2004;164:1534-40.
8. Namiki M. Antioxidants/antimutagens in food. Crit Rev Food Sci Nutr 1990;29:273-300.
9. Dambolena JS, Zunino MP, López AG, Rubinstein HR, Zygadlo JA, Mwangi JW, et al. Essential oils composition of Ocimum basilicum L. and Ocimum gratissimum L. from Kenya and their inhibitory effects on growth and fumonisin production by Fusarium verticillioides. Innov Food Sci Emerg Tech 2010;11:410-4.
10. Silva MG, Craveiro AA, Matos FJ, Machado MI, Alencar JW. Chemical variation during daytime of constituents of the essential oil of Ocimum gratissimum leaves. Fitoterapia 1999;70:32-4. (Pubitemid 29230102)
11. Matasyoh LG, Matasyoh JC, Wachira FN, Kinyua MG, Muigai AW, Mukiama TK. Chemical composition and antimicrobial activity of the essential oil of Ocimum gratissimum L. growing in Eastern Kenya. Afr J Biotechnol 2007;6:760-5. (Pubitemid 46525043)
12. Silva MG, Matos FJ, Lopes PR, Silva FO, Holanda MT. Composition of essential oils from three Ocimum species obtained by steam and microwave distillation and supercritical CO2 extraction. ARKIVOC 2004;6:66-71.
13. Suanarunsawat T, Ayutthaya WD, Songsak T, Thirawarapan S, Poungshompoo S. Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with a high cholesterol diet. J Clin Biochem Nutr 2010;46:52-9.
14. Khan A, Ahmad A, Akhtar F, Yousuf S, Xess I, Khan LA, et al. Ocimum sanctum essential oil and its active principles exert their antifungal activity by disrupting ergosterol biosynthesis and membrane integrity. Res Microbiol 2010;161:816-23.
15. Vani SR, Cheng SF, Chuah CH. Comparative Study of volatile compounds from genus Ocimum. Am J Appl Sci 2009;6:523-8.
16. Khan A, Ahmad A, Manzoor N, Khan LA. Antifungal activities of Ocimum sanctum essential oil and its lead molecules. Nat Prod Commun 2010;5:345-9.
17. Joshi RK. GC/MS analysis of the essential oil of Senecio belgaumensis flowers. Nat Prod Commun 2011;6:1145-6.
18. Adams RP. Identification of essential oil components by gas chromatography/mass spectroscopy. Carol Stream, Illinois, USA: Allured Publication; 2007.
19. Pujol V, Seux V, Villard J. Recherche de substances antifongiques secretes par les champignons superieurs en culture. Ann Pharm Fr 1990;48:17-22. (Pubitemid 20302668)
20. Joshi RK. In vitro antimicrobial and antioxidant activities of the essential oil of Craniotome furcata. J Appl Nat Sci 2010;2:57-62.
21. McFarland J. Standardization of bacterial culture for the disc diffusion assay. J Am Med Assoc 1987;49:1176-8.
22. Joshi RK. Chemical constituents and antibacterial property of the essential oil of the roots of Cyathocline purpurea. J Ethnopharmacol 2013;145:621-5.
23. Hou WC, Chen YC, Chen HJ, Lin YH, Yang LL, Lee MH. Antioxidant activities of trypsin inhibitor, a 33 KDa root storage protein of sweet potato (Ipomoea batatas (L.) Lam cv. Tainong 57. J Agric Food Chem 2001;49:2978-81.
24. Pellegrini N, Re R, Yang M, Rice-Evans C. Screening of dietary carotenoids and carotenoid-rich fruit extracts for antioxidant activities applying 2, 2'azinobis (3-ethyenebenzothiazoline-6-sulfonic acid) radical cation decolourization assay. Methods Enzymol 1999;299:379-89. (Pubitemid 28483910)
25. Wan J, Wilcock A, Coventry MJ. The effect of essential oils of basil on the growth of Aeromonas hydrophila and Pseudomonas fluorescens. Appl Microbiol 1998;84:152-8. (Pubitemid 28137000)
26. Inouye S, Yamaguchi H, Takizawa T. Screening of the antibacterial effects of variety of essential oils on respiratory tract pathogens, using a modified dilution assay method. J Infect Chemother 2001;7:251-4. (Pubitemid 34101076)
27. Ultee A, Kets EP, Smid EJ. Mechanisms of action of carvacrol on the food-borne pathogen Bacillus cereus. Appl Environ Microbiol 1999;65:4606-10.
28. Juven BJ, Kanner J, Schued F, Weisslowicz H. Factors that interact with the antibacterial action of thyme essential oil and its active constituents. J Appl Bacteriol 1994;76:626-31. (Pubitemid 24234567)