Ewing sarcoma of the thyroid: Report of 2 cases and review of the literature

Head and Neck

Volumn 35, Issue 11, 2013, Pages

  Chan, Jon M ^a   Bilodeau, Elizabeth ^b   Celin, Scott ^c   Nikiforov, Yuri ^a   Johnson, Jonas T ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c Metroplitan ENT Associates   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CD99 ANTIGEN; CHROMOGRANIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; SYNAPTOPHYSIN; VINCRISTINE;

ADULT; AGED; ANAMNESIS; ARTICLE; CALCITONIN BLOOD LEVEL; CANCER RADIOTHERAPY; CASE REPORT; CHROMATIN; CHROMOSOME 22Q; DIFFERENTIAL DIAGNOSIS; EPITHELIOID CELL; EWING SARCOMA; FINE NEEDLE ASPIRATION BIOPSY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; NECK DISSECTION; NECK TUMOR; NEUROECTODERM TUMOR; NEUROENDOCRINE TUMOR; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; THYROID CANCER; THYROID EWING SARCOMA; THYROID GLAND; THYROID MASS; THYROID NEUROENDOCRINE TUMOR; THYROIDECTOMY; TUMOR CELL; ULTRASOUND;

AGED; BIOPSY, NEEDLE; CHEMOTHERAPY, ADJUVANT; DIAGNOSIS, DIFFERENTIAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPH NODES; MALE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NEUROENDOCRINE TUMORS; RARE DISEASES; SARCOMA, EWING; THYROID NEOPLASMS; THYROIDECTOMY; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84886405039     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.23240     Document Type: Article

References (22)

1. American Thyroid Association Guidelines Task Force, Kloos RT, Eng C, et al. Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid 2009; 19: 565-612.
2. Bockhorn M, Sheu SY, Frilling A, Molmenti E, Schmid KW, Broelsch CE,. Paraganglioma-like medullary thyroid carcinoma: a rare entity. Thyroid 2005; 15: 1363-1367.
3. Ryska A, Cap J, Vaclavikova E, et al. Paraganglioma-like medullary thyroid carcinoma: fine needle aspiration cytology features with histological correlation. Cytopathology 2009; 20: 188-194.
4. Sand M, Gelos M, Sand D, et al. Serum calcitonin negative medullary thyroid carcinoma. World J Surg Oncol 2006; 4: 97.
5. Bockhorn M, Frilling A, Rewerk S, et al. Lack of elevated serum carcinoembryonic antigen and calcitonin in medullary thyroid carcinoma. Thyroid 2004; 14: 468-470.
6. La Rosa S, Imperatori A, Giovanella L, Garancini S, Capella C,. Thyroid metastases from typical carcinoid of the lung differentiating between medullary thyroid carcinoma and neuroendocrine tumor metastasis to the thyroid. Thyroid 2009; 19: 521-526.
7. Chico A, Pallarés MC, Matías-Guiu X, Ciprés L, Puig-Domingo M, Webb SM,. Bronchial carcinoid tumor presenting as a thyroid nodule: an unusual clinical manifestation. J Endocrinol Invest 1996; 19: 186-189.
8. Matias-Guiu X, LaGuette J, Puras-Gil AM, Rosai J,. Metastatic neuroendocrine tumors to the thyroid gland mimicking medullary carcinoma: a pathologic and immunohistochemical study of six cases. Am J Surg Pathol 1997; 21: 754-762.
9. Leboulleux S, Baudin E, Young J, et al. Gastroenteropancreatic neuroendocrine tumor metastases to the thyroid gland: differential diagnosis with medullary thyroid carcinoma. Eur J Endocrinol 1999; 140: 187-191.
10. Biswas G, Hingmire S, Bagwan I, et al. Primitive neuroectodermal tumor (PNET) of thyroid. Oral Oncol Extra 2006; 42; 198-199.
11. Adapa P, Chung TW, Popek EJ, Hunter JV,. Extraosseous Ewing sarcoma of the thyroid gland. Pediatr Radiol 2009; 39: 1365-1368.
12. Chang TC, Wu SL, Hsiao YL,. Medullary thyroid carcinoma: pitfalls in diagnosis by fine needle aspiration cytology and relationship of cytomorphology to RET proto-oncogene mutations. Acta Cytol 2005; 49: 477-482.
13. Binderup T, Knigge U, Loft A, et al. Functional imaging of neuroendocrine tumors: a head-to-head comparison of somatostatin receptor scintigraphy, 123I-MIBG scintigraphy, and 18F-FDG PET. J Nucl Med 2010; 51: 704-712.
14. Garin E, Le Jeune F, Devillers A, et al. Predictive value of 18F-FDG PET and somatostatin receptor scintigraphy in patients with metastatic endocrine tumors. J Nucl Med 2009; 50: 858-864.
15. Mendelsohn G, Wells SA Jr, Baylin SB,. Relationship of tissue carcinoembryonic antigen and calcitonin to tumor virulence in medullary thyroid carcinoma. An immunohistochemical study in early, localized, and virulent disseminated stages of disease. Cancer 1984; 54: 657-662.
16. Llombart-Bosch A, Navarro S,. Immunohistochemical detection of EWS and FLI-1 proteins in Ewing sarcoma and primitive neuroectodermal tumors: comparative analysis with CD99 (MIC-2) expression. Appl Immunohistochem Mol Morphol 2001; 9: 255-260.
17. de Groot JW, Links TP, Plukker JT, Lips CJ, Hofstra RM,. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. Endocr Rev 2006; 27: 535-560.
18. Delattre O, Zucman J, Melot T, et al. The Ewing family of tumors-a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 1994; 331: 294-299.
19. Carvajal R, Meyers P,. Ewing's sarcoma and primitive neuroectodermal family of tumors. Hematol Oncol Clin N Am 2005; 19: 501-525.
20. Zoubek A, Ladenstein R, Windhager R, et al. Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: a preliminary evaluation. Int J Cancer 1998; 79: 56-60.
21. Ahmad R, Mayol BR, Davis M, Rougraff BT,. Extraskeletal Ewing's sarcoma. Cancer 1999; 85: 725-731.
22. Grier HE, Krailo MD, Tarbell NJ, et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med 2003; 348: 694-701.