Remote ischemic post-conditioning of the lower limb during primary percutaneous coronary intervention safely reduces enzymatic infarct size in anterior myocardial infarction: A randomized controlled trial

JACC: Cardiovascular Interventions

Volumn 6, Issue 10, 2013, Pages 1055-1063

  Crimi, Gabriele ^a,b   Pica, Silvia ^a   Raineri, Claudia ^a   Bramucci, Ezio ^a   De Ferrari, Gaetano M ^a   Klersy, Catherine ^c   Ferlini, Marco ^a   Marinoni, Barbara ^a   Repetto, Alessandra ^a   Romeo, Maurizio ^b   Rosti, Vittorio ^c   Massa, Margherita ^c   Raisaro, Arturo ^a   Leonardi, Sergio ^a   Rubartelli, Paolo ^b   Oltrona Visconti, Luigi ^a   Ferrario, Maurizio ^a  

^a C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^b VILLA SCASSI HOSPITAL   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

cardiac magnetic resonance imaging; myocardial conditioning; myocardial infarction; myocardial reperfusion injury; primary angioplasty

Indexed keywords

CREATINE KINASE MB;

ADULT; AGED; ANTERIOR MYOCARDIAL INFARCTION; AREA UNDER THE CURVE; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DELAYED ENHANCEMENT VOLUME; FEMALE; HEART INFARCTION SIZE; HUMAN; IMAGE ANALYSIS; ISCHEMIC POSTCONDITIONING; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LEG; MAJOR CLINICAL STUDY; MALE; MYOCARDIAL BLUSH GRADING; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PNEUMATIC CUFF; PRIORITY JOURNAL; RADIOLOGICAL PARAMETERS; RANDOMIZED CONTROLLED TRIAL; REMOTE ISCHEMIC POSTCONDITIONING; REPERFUSION INJURY; SINGLE BLIND PROCEDURE; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; ST SEGMENT RESOLUTION; T2 WEIGHTED EDEMA VOLUME; THROMBOLYSIS IN MYOCARDIAL INFARCTION FRAME COUNT;

ANTI-GP IIB/IIIA; CARDIAC MAGNETIC RESONANCE IMAGING; CE-CMR; CI; CK-MB; CONFIDENCE INTERVAL; CONTRAST ENHANCED CARDIAC MAGNETIC RESONANCE; CREATINE KINASE-MYOCARDIAL BAND; DE; DELAYED ENHANCEMENT; INHIBITORS OF GLYCOPROTEIN IIB/IIIA; INTERQUARTILE RANGE; IQR; LAD; LEFT ANTERIOR DESCENDING; LEFT VENTRICLE/VENTRICULAR; LV; MBG; MYOCARDIAL BLUSH GRADING; MYOCARDIAL CONDITIONING; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; PPCI; PRIMARY ANGIOPLASTY; PRIMARY PERCUTANEOUS CORONARY INTERVENTION; REMOTE ISCHEMIC POST-CONDITIONING; RIPC; ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION; ST-SEGMENT RESOLUTION; STEMI; STR; T(2)-WEIGHTED; T2W; THROMBOLYSIS IN MYOCARDIAL INFARCTION; TIMI;

AGED; ANTERIOR WALL MYOCARDIAL INFARCTION; AREA UNDER CURVE; BIOLOGICAL MARKERS; CREATINE KINASE, MB FORM; FEMALE; HUMANS; ISCHEMIC POSTCONDITIONING; ITALY; LOWER EXTREMITY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE OF TESTS; ROC CURVE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84886385820     PISSN: 19368798     EISSN: 18767605     Source Type: Journal    
DOI: 10.1016/j.jcin.2013.05.011     Document Type: Article

References (28)

1. D.J. Gwilt, M. Petri, P.W. Lewis, M. Nattrass, and B.L. Pentecost Myocardial infarct size and mortality in diabetic patients Br Heart J 54 1985 466 472
2. F. Zijsta, J.C. Hoorntje, and M.J. De Boer Long-term benefit of primary angioplasty as compared with thrombolytic therapy for acute myocardial infarction N Eng J Med 341 1999 1413 1419
3. D.M. Yellon, and D.J. Hausenloy Myocardial reperfusion injury N Engl J Med 357 2007 1121 1135
4. Z.Q. Zhao, J.S. Corvera, and M.E. Halkos Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning Am J Physiol Heart Circ Physiol 285 2003 H579 H588
5. P. Staat, and Piot C. RioufolG Postconditioning the human heart Circulation 112 2005 2143 2148
6. X. Ma, X. Zhang, C. Li, and M. Luo Effect of postconditioning on coronary blood flow velocity and endothelial function and LV recovery after myocardial infarction J Interv Cardiol 19 2006 367 375
7. W.K. Laskey, S. Yoon, N. Calzada, and M.J. Ricciardi Concordant improvements in coronary flow reserve and ST-segment resolution during percutaneous coronary intervention for acute myocardial infarction: a benefit of postconditioning Catheter Cardiovasc Interv 72 2008 212 220
8. X.C. Yang, Y. LIU, and L.F. Wang Reduction in myocardial infarct size by postconditioning patients after percutaneous coronary interventions J Invasive Cardiol 19 2007 424 430
9. J. Løngborg, H. Kelbaek, and N. Vejlstrup Cardioprotective effect of ischemic postconditioning in patients treated with primary percutaneous coronary intervention, evaluated by magnetic resonance Circ Cardiovasc Interv 3 2010 34 41
10. P. Sörennson, N. Saleh, and F. Bouvier Effect of postconditioning on infarct size in patients with ST elevation myocardial infarction Heart 96 2010 1710 1715
11. j Freixa, N. Bellera, and J.T. Ortiz-Pérez Ischaemic postconditioning revisited: lack of effect on infarct size following primary percutaneous coronary intervention Eur Heart J 33 2012 103 112
12. G. Tarantini, E. Favaretto, and M.P. Marra Postconditioning during coronary angioplasty in acute myocardial infarction: the POST-AMI trial Int J Cardiol 162 2012 33 38
13. K. Przyklenk, B. Bauer, M. Ovize, R. Kloner, and P. Whittaker Regional ischemic "preconditioning" protects remote virgin myocardium from subsequent sustained occlusion Circulation 87 1993 893 899
14. G. Andreka, M. Vertesaljai, and G. Szantho Remote ischaemic postconditioning protects the heart during acute myocardial infarction in pig Heart 93 2007 749 752
15. G. Gritsopoulos, E.K. Iliodromitis, and A. Zoga Remote postconconditioning is more potent than classic postconditioning in reducing infarct size in anesthetized rabbits Cardiovasc Drug Ther 23 2009 193 198
16. H.E. Bøtker, R. Kharbanda, and M.R. Schmidt Remote ischemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomized trial Lancet 375 2010 727 734
17. F. Thuny, O. Lairez, and F. Roubille Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction J Am Coll Cardiol 59 2012 2175 2181
18. P. Grande, B.F. Hansen, C. Christiansen, and J. Naestoft Estimation of acute myocardial infarct size in man by serum CK-MB measurement Circulation 65 1982 756 764
19. C.M. Gibson, C.P. Cannon, and W.L. Daley TIMI frame count: a quantitative method of assessing coronary artery flow Circulation 93 1996 897 898
20. A.W. Van 't Hof, A. Liem, H. Suryapranata for the Zwolle Myocardial Infarction Study Group Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade Circulation 97 1998 2302 2306
21. R. Schröder Prognostic impact of early ST-segment resolution in acute ST-elevation myocardial infarction Circulation 110 2004 e506 e510
22. S.J. Pocock Current controversies in data monitoring for clinical trials Clin Trials 3 2006 513 521
23. K.F. Schulz, D.G. Altman, D. Moher for the CONSORT Group CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials Ann Intern Med 152 2010 726 732
24. I. Rentoukas, G. Giannopoulos, and A. Kaoukis Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary interventions J Am Coll Cardiol Intv 3 2010 49 55
25. S.P. Loukogeorgakis, R. William, and A.T. Panangiotidou Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism Circulation 116 2007 1386 1395
26. D. Garcia-Dorado, and J. Oliveras Myocardial oedema: a preventable cause of reperfusion injury? Cardiovasc Res 27 1993 1555 1563
27. M.G. Friedrich Myocardial edema - a new clinical entity? Nat Rev Cardiol 7 2010 292 296
28. J.A. de Lemos, and E. Braunwald ST segment resolution as a tool for assessing the efficacy of reperfusion therapy J Am Coll Cardiol 30 2001 1283 1294