Fabrication of a biodegradable xenoantigen-free rat liver scaffold for potential drug screening applications

Transplantation Proceedings

Volumn 45, Issue 8, 2013, Pages 3092-3096

  Hussein, K H ^a   Park, K M ^a   Teotia, P K ^a   Yang, J W ^a   Kim, H M ^a   Hong, S H ^a   Yang, S R ^a   Park, I C ^a   Park, S M ^a   Woo, H M ^a,b  

^a Kangwon National University   (South Korea)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DNA; GLYCOSAMINOGLYCAN; HETEROANTIGEN; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

ANIMAL TISSUE; CHEMICAL ANALYSIS; CONFERENCE PAPER; DRUG SCREENING; EXTRACELLULAR MATRIX; HISTOLOGY; LIVER; MIXED LYMPHOCYTE REACTION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIGENS; BIOCOMPATIBLE MATERIALS; DRUG SCREENING ASSAYS, ANTITUMOR; LIVER; LYMPHOCYTE CULTURE TEST, MIXED; RATS; TISSUE SCAFFOLDS;

EID: 84886301269     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2013.08.016     Document Type: Conference Paper

References (11)

1. N.T. Elliott, and F. Yuan A review of three-dimensional in vitro tissue models for drug discovery and transport studies J Pharm Sci 100 2011 59
2. B. Altmann, S. Giselbrecht, and K.-F. Weibezahn The three-dimensional cultivation of the carcinoma cell line HepG2 in a perfused chip system leads to a more differentiated phenotype of the cells compared to monolayer culture Biomed Mater 3 2008 034120
3. L.G. Griffith, and M.A. Swartz Capturing complex 3D tissue physiology in vitro Nat Rev Mol Cell Biol 7 2006 211
4. L. Sang, D. Luo, and S. Xu Fabrication and evaluation of biomimetic scaf folds by using collagen-alginate fibrillar gels for potential tissue engineering applications Mater Sci Eng 31 2011 262
5. G.D. Prestwich Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery Acc Chem Res 41 2008 139
6. T. Shupe, M. Williams, and A. Brown Method for the dccellularization of intact rat liver Organogenesis 6 2010 134
7. P.M. Baptista, G. Orlando, and S.H. Mirmalek-Sani Whole organ decellularization: a tool for bioscaffold fabrication and organ bioengineering Conf Proc IEEE Eng Med Biol Soc 6526 2009 2009
8. A. Soto-Gutierrez, L. Zhang, and C. Medberry A whole-organ regenerative medicine approach for liver replacement Tissue Eng Part C Methods 17 2011 677
9. B.E. Uygun, A. Soto-Gutierrez, and H. Yagi Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix Nat Med 16 2010 814
10. E. Kheir, T. Stapleton, and D. Shaw Development and characterization of an acellular porcine cartilage bone matrix for use in tissue engineering J Biomed Mater Res A 99 2011 283
11. K.M. Park, and H.M. Woo Systemic decellularization for multi-organ scaffolds in rats Transplant Proc 44 2012 1151