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Volumn 15, Issue 85, 2013, Pages 333-341

Towards the goal of personalized medicine in gastric cancer - Time to move beyond HER2 inhibition. Part I: Targeting receptor tyrosine kinase gene amplification

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

EID: 84886295592     PISSN: 15396509     EISSN: 19447930     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (58)
  • 1
    • 49049106960 scopus 로고    scopus 로고
    • The impact of ethnicity on the presentation and prognosis of patients with gastric adenocarcinoma
    • Results from the National Cancer Data Base
    • Al-Refaie WB, Tseng JF, Gay G, Patel-Parekh L, Mansfield PF, Pisters PW, Yao JC, Feig BW. The impact of ethnicity on the presentation and prognosis of patients with gastric adenocarcinoma. Results from the National Cancer Data Base. Cancer 113(3):461-469, 2008.
    • (2008) Cancer , vol.113 , Issue.3 , pp. 461-469
    • Al-Refaie, W.B.1    Tseng, J.F.2    Gay, G.3    Patel-Parekh, L.4    Mansfield, P.F.5    Pisters, P.W.6    Yao, J.C.7    Feig, B.W.8
  • 2
    • 84555202728 scopus 로고    scopus 로고
    • MET signaling pathway: A rational target for cancer therapy
    • Appleman LJ. MET signaling pathway: A rational target for cancer therapy. J Clin Oncol 29(36):4837-4838, 2011.
    • (2011) J Clin Oncol , vol.29 , Issue.36 , pp. 4837-4838
    • Appleman, L.J.1
  • 3
    • 70450209516 scopus 로고    scopus 로고
    • Pathological features of advanced gastric cancer (GC): Relationship to human epidermal growth factor receptor 2 (HER2) positivity in the global screening programme of the ToGA trial
    • abstr#4556
    • Bang Y, Chung H, Xu J, Lordick F, Sawaki A, Lipatov O, Al-Sakaff N, See C, Rueschoff J, Van Cutsem E. Pathological features of advanced gastric cancer (GC): Relationship to human epidermal growth factor receptor 2 (HER2) positivity in the global screening programme of the ToGA trial. J Clin Oncol 27(suppl):abstr#4556, 2009.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Bang, Y.1    Chung, H.2    Xu, J.3    Lordick, F.4    Sawaki, A.5    Lipatov, O.6    Al-Sakaff, N.7    See, C.8    Rueschoff, J.9    Van Cutsem, E.10
  • 4
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esophageal junction cancer (ToGA): a phase 3 open-label randomized controlled trial
    • ToGA Trial Investigators
    • Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Rüschoff J, Kang YK; ToGA Trial Investigators. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esophageal junction cancer (ToGA): a phase 3 open-label randomized controlled trial. Lancet 376(9742):687-697, 2010.
    • (2010) Lancet , vol.376 , Issue.9742 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6    Lordick, F.7    Ohtsu, A.8    Omuro, Y.9    Satoh, T.10    Aprile, G.11    Kulikov, E.12    Hill, J.13    Lehle, M.14    Rüschoff, J.15    Kang, Y.K.16
  • 5
    • 84877605189 scopus 로고    scopus 로고
    • A randomized, open-label, phase III study of lapatinib in combination with weekly paclitaxel versus weekly paclitaxel alone in the second-line treatment of HER2 amplified advanced gastric cancer (AGC) in Asian population: Tytan study
    • abstr#11
    • Bang YJ. A randomized, open-label, phase III study of lapatinib in combination with weekly paclitaxel versus weekly paclitaxel alone in the second-line treatment of HER2 amplified advanced gastric cancer (AGC) in Asian population: Tytan study. J Clin Oncol 30(suppl 34):abstr#11, 2012.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL. 34
    • Bang, Y.J.1
  • 6
    • 77950819136 scopus 로고    scopus 로고
    • The analysis of PIK3CA mutations in gastric carcinoma and metaanalysis of literature suggest that exon-selectivity is a signature of cancer type
    • Barbi S, Cataldo I, De Manzoni G, Bersani S, Lamba S, Mattuzzi S, Bardelli A, Scarpa A. The analysis of PIK3CA mutations in gastric carcinoma and metaanalysis of literature suggest that exon-selectivity is a signature of cancer type. J Exp Clin Cancer Res 29:32, 2010.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 32
    • Barbi, S.1    Cataldo, I.2    De Manzoni, G.3    Bersani, S.4    Lamba, S.5    Mattuzzi, S.6    Bardelli, A.7    Scarpa, A.8
  • 8
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signaling
    • Blume-Jensen P, Hunter T. Oncogenic kinase signaling. Nature 411(6835):355-365, 2001.
    • (2001) Nature , vol.411 , Issue.6835 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 9
    • 84874028989 scopus 로고    scopus 로고
    • Towards personalized therapy for patients with malignant melanoma: molecular insights into the biology of BRAF mutations
    • Bradish JR, Montironi R, Lopez-Beltran A, Post KM, MacLennan GT, Cheng L. Towards personalized therapy for patients with malignant melanoma: molecular insights into the biology of BRAF mutations. Future Oncol 9(2):245-253, 2013.
    • (2013) Future Oncol , vol.9 , Issue.2 , pp. 245-253
    • Bradish, J.R.1    Montironi, R.2    Lopez-Beltran, A.3    Post, K.M.4    MacLennan, G.T.5    Cheng, L.6
  • 10
    • 84859415553 scopus 로고    scopus 로고
    • Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
    • Brooks AN, Kilgour E, Smith PD. Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer. Clin Cancer Res 18(7):1855-1862, 2012.
    • (2012) Clin Cancer Res , vol.18 , Issue.7 , pp. 1855-1862
    • Brooks, A.N.1    Kilgour, E.2    Smith, P.D.3
  • 15
    • 84876048479 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives
    • Dieci MV, Arnedos M, Andre F, Soria JC. Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives. Cancer Discov 3(3):264-79, 2013.
    • (2013) Cancer Discov , vol.3 , Issue.3 , pp. 264-279
    • Dieci, M.V.1    Arnedos, M.2    Andre, F.3    Soria, J.C.4
  • 19
    • 0038545199 scopus 로고    scopus 로고
    • Asian ethnicity-related differences in gastric cancer presentation and outcome among patients treated at a Canadian cancer center
    • Gill S, Shah A, Le N, Cook EF, Yoshida EM. Asian ethnicity-related differences in gastric cancer presentation and outcome among patients treated at a Canadian cancer center. J Clin Oncol 21(11):2070-2076, 2003.
    • (2003) J Clin Oncol , vol.21 , Issue.11 , pp. 2070-2076
    • Gill, S.1    Shah, A.2    Le, N.3    Cook, E.F.4    Yoshida, E.M.5
  • 21
    • 50849123421 scopus 로고    scopus 로고
    • HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
    • Gravalos C, Jimeno A. HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol 19(9):1523-1529, 2008.
    • (2008) Ann Oncol , vol.19 , Issue.9 , pp. 1523-1529
    • Gravalos, C.1    Jimeno, A.2
  • 28
    • 0035328856 scopus 로고    scopus 로고
    • Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers
    • Jang JH, Shin KH, Park JG. Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers. Cancer Res 61(9):3541-3543, 2001.
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3541-3543
    • Jang, J.H.1    Shin, K.H.2    Park, J.G.3
  • 31
    • 84866516574 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma
    • Jung EJ, Jung EJ, Min SY, Kim MA, Kim WH. Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma. Hum Pathol 43(10):1559-1566, 2012.
    • (2012) Hum Pathol , vol.43 , Issue.10 , pp. 1559-1566
    • Jung, E.J.1    Jung, E.J.2    Min, S.Y.3    Kim, M.A.4    Kim, W.H.5
  • 32
    • 84877091049 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of FGF receptor 2 (FGFR2) gene amplification in Caucasian and Korean gastric cancer cohorts
    • abstr#4124
    • Kilgour E, Su X, Zhan P, Gavine P, Morgan S, Womack C, Jung EJ, Bang YJ, Im SA, Kim WH, Grabsch H. Prevalence and prognostic significance of FGF receptor 2 (FGFR2) gene amplification in Caucasian and Korean gastric cancer cohorts. J Clin Oncol 30(suppl):abstr#4124, 2012.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Kilgour, E.1    Su, X.2    Zhan, P.3    Gavine, P.4    Morgan, S.5    Womack, C.6    Jung, E.J.7    Bang, Y.J.8    Im, S.A.9    Kim, W.H.10    Grabsch, H.11
  • 34
    • 42649133793 scopus 로고    scopus 로고
    • EGFR in gastric carcinomas: prognostic significance of protein overexpression and high gene copy number
    • Kim MA, Lee HS, Lee HE, Jeon YK, Yang HK, Kim WH. EGFR in gastric carcinomas: prognostic significance of protein overexpression and high gene copy number. Histopathology 52(6):738-746, 2008.
    • (2008) Histopathology , vol.52 , Issue.6 , pp. 738-746
    • Kim, M.A.1    Lee, H.S.2    Lee, H.E.3    Jeon, Y.K.4    Yang, H.K.5    Kim, W.H.6
  • 35
    • 79955425807 scopus 로고    scopus 로고
    • Randomized phase II study of nimotuzumab, an anti-EGFR antibody, plus irinotecan in patients with 5-fluorouracil-based regimen-refractory advanced or recurrent gastric cancer in Korea and Japan: Preliminary results
    • abstr#87
    • Kim YH, Sasaki Y, Lee KH, Rha SY, Park S, Boku N, Komatsu Y, Kim T, Kim S, Sakata Y. Randomized phase II study of nimotuzumab, an anti-EGFR antibody, plus irinotecan in patients with 5-fluorouracil-based regimen-refractory advanced or recurrent gastric cancer in Korea and Japan: Preliminary results. J Clin Oncol 29(suppl 4):abstr#87, 2011.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. 4
    • Kim, Y.H.1    Sasaki, Y.2    Lee, K.H.3    Rha, S.Y.4    Park, S.5    Boku, N.6    Komatsu, Y.7    Kim, T.8    Kim, S.9    Sakata, Y.10
  • 39
    • 84863719409 scopus 로고    scopus 로고
    • MET in gastric carcinomas: comparison between protein expression and gene copy number and impact on clinical outcome
    • Lee HE, Kim MA, Lee HS, Jung EJ, Yang HK, Lee BL, Bang YJ, Kim WH. MET in gastric carcinomas: comparison between protein expression and gene copy number and impact on clinical outcome. Br J Cancer 107(2):325-333, 2012.
    • (2012) Br J Cancer , vol.107 , Issue.2 , pp. 325-333
    • Lee, H.E.1    Kim, M.A.2    Lee, H.S.3    Jung, E.J.4    Yang, H.K.5    Lee, B.L.6    Bang, Y.J.7    Kim, W.H.8
  • 42
    • 84875937242 scopus 로고    scopus 로고
    • Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies
    • Li T, Kung HJ, Mack PC, Gandara DR. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol 31(8):1039-1049, 2013.
    • (2013) J Clin Oncol , vol.31 , Issue.8 , pp. 1039-1049
    • Li, T.1    Kung, H.J.2    Mack, P.C.3    Gandara, D.R.4
  • 43
    • 84876951761 scopus 로고    scopus 로고
    • Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial
    • on behalf of the Arbeitsgemeinschaft Internistische Onkologie (AIO) and EXPAND Investigators,
    • Lordick F, Kang YK, Chung HC, Salman P, Oh SC, Bodoky G, Kurteva G, Volovat C, Moiseyenko VM, Gorbunova V, Park JO, Sawaki A, Celik I, Götte H, Melezínková H, Moehler M; on behalf of the Arbeitsgemeinschaft Internistische Onkologie (AIO) and EXPAND Investigators. Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial. Lancet Oncol 14(6):490-499, 2013.
    • (2013) Lancet Oncol , vol.14 , Issue.6 , pp. 490-499
    • Lordick, F.1    Kang, Y.K.2    Chung, H.C.3    Salman, P.4    Oh, S.C.5    Bodoky, G.6    Kurteva, G.7    Volovat, C.8    Moiseyenko, V.M.9    Gorbunova, V.10    Park, J.O.11    Sawaki, A.12    Celik, I.13    Götte, H.14    Melezínková, H.15    Moehler, M.16
  • 46
    • 84858669035 scopus 로고    scopus 로고
    • Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap? A review of the clinical evidence
    • Ou SH. Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap? A review of the clinical evidence. Crit Rev Oncol Hematol 83(3):407-421, 2012.
    • (2012) Crit Rev Oncol Hematol , vol.83 , Issue.3 , pp. 407-421
    • Ou, S.H.1
  • 47
    • 78650412305 scopus 로고    scopus 로고
    • Targeting RET receptor tyrosine kinase activation in cancer
    • Phay JE, Shah MH. Targeting RET receptor tyrosine kinase activation in cancer. Clin Cancer Res 16(24):5936-5941, 2010.
    • (2010) Clin Cancer Res , vol.16 , Issue.24 , pp. 5936-5941
    • Phay, J.E.1    Shah, M.H.2
  • 53
    • 20044372721 scopus 로고    scopus 로고
    • Amplification of HER-2 in gastric carcinoma: association with Topoisomerase II alpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab
    • Tanner M, Hollmén M, Junttila TT, Kapanen AI, Tommola S, Soini Y, Helin H, Salo J, Joensuu H, Sihvo E, Elenius K, Isola J. Amplification of HER-2 in gastric carcinoma: association with Topoisomerase II alpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab. Ann Oncol 16(2):273-278, 2005.
    • (2005) Ann Oncol , vol.16 , Issue.2 , pp. 273-278
    • Tanner, M.1    Hollmén, M.2    Junttila, T.T.3    Kapanen, A.I.4    Tommola, S.5    Soini, Y.6    Helin, H.7    Salo, J.8    Joensuu, H.9    Sihvo, E.10    Elenius, K.11    Isola, J.12
  • 54
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: from development to cancer
    • Turner N, Grose R. Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer 10(2):116-129, 2010.
    • (2010) Nat Rev Cancer , vol.10 , Issue.2 , pp. 116-129
    • Turner, N.1    Grose, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.