Anxiolytics in patients suffering a suspected acute coronary syndrome: Multi-centre randomised controlled trial in Emergency Medical Service

International Journal of Cardiology

Volumn 168, Issue 4, 2013, Pages 3580-3587

  Sundström, Birgitta Wireklint ^a   Bång, Angela ^a   Karlsson, Thomas ^b   Winge, Karin ^c   Lundberg, Camilla ^c   Herlitz, Johan ^a  

^a UNIVERSITY OF BORÅS   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c Section of Rheumatology   (Sweden)

Author keywords

Anxiety; Benzodiazepine; Cardiology nursing; Chest pain; Emergency Medical Services

Indexed keywords

MIDAZOLAM; MORPHINE;

ACUTE CORONARY SYNDROME; ADULT; AGED; ALERTNESS; ANXIETY; ARM PAIN; ARTICLE; BACKACHE; BREATHING RATE; COLD SWEAT; CONTROLLED STUDY; DROWSINESS; DYSPNEA; EMERGENCY HEALTH SERVICE; FEMALE; HEART FAILURE; HEART RATE; HEART SUPRAVENTRICULAR ARRHYTHMIA; HOSPITAL ADMISSION; HUMAN; HYPOTENSION; JAW PAIN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; NECK PAIN; PAIN ASSESSMENT; PALLOR; PRIORITY JOURNAL; PULSE OXIMETRY; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SIDE EFFECT; STOMACH PAIN; SYSTOLIC BLOOD PRESSURE; THORAX PAIN; VOMITING;

ANXIETY; BENZODIAZEPINE; CARDIOLOGY NURSING; CHEST PAIN; EMERGENCY MEDICAL SERVICES;

ACUTE CORONARY SYNDROME; AGED; AGED, 80 AND OVER; ANTI-ANXIETY AGENTS; ANXIETY; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 84886283955     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.05.067     Document Type: Article

References (21)

1. J. Herlitz, A. Richter, and Å. Hjalmarson Chest pain in acute myocardial infarction. A descriptive study according to subjective assessment and morphine requirement Clin Cardiol 9 1986 423 428
2. M. Gardtman, M. Dellborg, and Ch. Brunnhage Effect of intravenous metoprolol before hospital admission on chest pain in suspected acute myocardial infarction Am Heart J 137 1999 821 829
3. C. Zedigh, A. Alho, and E. Hammar Aspects on the intensity and the relief of pain in the pre-hospital phase of acute coronary syndrome: experiences from a randomised clinical trial Coron Artery Dis 21 2010 113 120
4. M.J. De Jong, M.L. Chung, and L.P. Roser A five-country comparison of anxiety early after acute myocardial infarction Eur J Cardiovasc Nurs 3 2004 129 134
5. M.A. Khan, M. Karamat, M. Hafizullah, Z. Nazar, M. Fahim, and A.M. Gul Frequency of anxiety and psychosocial stressful events in patients with acute myocardial infraction J Ayub Med Coll Abbottabad 22 2010 32 35
6. L. Guanghui, W. Xianzheng, and M. Wenlin Epidemiology and preventive medicine: epidemiology of cardiovascular disease: e0282 effect of comprehensive intervention on anxiety and depressive symptoms in patients after ACS Heart 96 Suppl. 3 2010 A89 A90
7. J. Herlitz, A. Bång, and E. Omerovic Is pre-hospital treatment of chest pain optimal? Both relief of pain and anxiety are needed Int J Cardiol 149 2011 147 151
8. COMMIT (Clopidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group Early intravenous then oral metoprolol in 45.852 patients with acute myocardial infarction: randomised placebo-controlled trial Lancet 366 2005 1622 1632
9. European Society of Cardiology The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation Eur Heart J 29 2008 2909 2945
10. American College of Cardiology/American Heart Association A report of the American College of Cardiology/American Heart Association Task Force on Practise Guidelines. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction Circulation 110 2004 e82 e293
11. P. McGrath, C. Seifert, and K. Speechley A new analogue scale for assessing children's pain: an initial validation study Pain 64 1996 435 443
12. S.A. McLean, R.M. Domeier, H.K. DeVore, E.M. Hill, R.F. Maio, and S.M. Fredriksen The feasibility of pain assessment in the pre-hospital setting Prehosp Emerg Care 8 2004 155 161
13. C. Leys, and S. Schumann A nonparametric method to analyze interactions: the adjusted rank transform test J Exp Soc Psychol 46 2010 684 688
14. M. Melsom, H. Andreassen, and T. Melsom Diazepam in acute myocardial infarction: clinical effects and effects on catecholamines, free fatty acids, and cortisol Br Heart J 38 1976 804 810
15. B.M. Baumann, J. Perrone, and S.E. Hornig Randomised double-blind, placebo-controlled trial of diazepam, nitroglycerin, or both for treatment of patients with potential cocaine-associated acute coronary syndromes Acad Emerg Med 7 2000 878 885
16. E. Rossetti, G. Fragasso, and R.G. Xuereb Antiischemic effects of intravenous diazepam in patients with coronary artery disease J Cardiovasc Pharmacol 24 1994 55 58
17. R.A. Dixon, I.R. Edwards, and J. Pilcher Diazepam in immediate post-myocardial infarct period. A double blind trial Br Heart J 43 1980 535 540
18. M. Vrana, L. Hess, and Z. Vranova An experimental contribution to the treatment of acute myocardial infarction Czech Med 10 1987 142 155
19. L. Hess, M. Vrana, and Z. Vranova The electrostabilizing effect of a combination of midazolam and fentanyl: an experimental study in the dog Cor Vasa 31 1989 411 418
20. M. Vrana, Z. Fejfar, and L. Hess Analgosedation-enhanced baroreflex sensitivity in acute local myocardial infarction Cor Vasa 33 1991 428 434
21. S. Baris, D. Karakaya, and T. Aykent Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography Can J Cardiol 173 2001 277 281