Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Sano, Akiko ^a,e   Matsushita, Hiroaki ^b,e   Wu, Hua ^b,e   Jiao, Jin An ^b,e   Kasinathan, Poothappillai ^d,e   Sullivan, Eddie J ^b,e   Wang, Zhongde ^c,e   Kuroiwa, Yoshimi ^a,e  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b Sanford Applied Biosciences LLC   (United States)

^c UTAH STATE UNIVERSITY   (United States)

^d Trans Ova Genetics   (United States)

^e Hematech Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD79A ANTIGEN; CD79B ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; POLYCLONAL ANTIBODY; PRE B CELL RECEPTOR;

ANIMAL CELL; ARTICLE; ARTIFICIAL CHROMOSOME; B LYMPHOCYTE ACTIVATION; CATTLE; CELL MATURATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; B-LYMPHOCYTES; CATTLE; CELL PROLIFERATION; CHROMOSOMES, ARTIFICIAL, HUMAN; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN MU-CHAINS; IMMUNOGLOBULINS;

EID: 84886259619     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078119     Document Type: Article

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