HDL cholesterol in cardiovascular diseases: The good, the bad, and the ugly?

International Journal of Cardiology

Volumn 168, Issue 4, 2013, Pages 3157-3159

  Xu, Suowen ^a,b   Liu, Zhiping ^c   Liu, Peiqing ^c  

^a SUN YAT SEN UNIVERSITY   (China)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NONE

Author keywords

Atherosclerosis; Chronic kidney disease; Coronary artery disease; HDL; LOX 1; TLR 2

Indexed keywords

ANACETRAPIB; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; DALCETRAPIB; EVACETRAPIB; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; REACTIVE OXYGEN METABOLITE; TORCETRAPIB;

ATHEROSCLEROSIS; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CELL MIGRATION; CELL PROLIFERATION; CHOLESTEROL TRANSPORT; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL (TOPIC); CORONARY ARTERY DISEASE; DRUG EFFICACY; DRUG SAFETY; ENDOTHELIAL DYSFUNCTION; FOAM CELL; HUMAN; LIPID ANALYSIS; MORTALITY; OXIDATIVE STRESS; PATHOGENESIS; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; RISK REDUCTION; SMOOTH MUSCLE FIBER;

ATHEROSCLEROSIS; CHRONIC KIDNEY DISEASE; CORONARY ARTERY DISEASE; HDL; LOX-1; TLR-2;

ANIMALS; ATHEROSCLEROSIS; HUMANS; HYPERTENSION; KIDNEY DISEASES; LIPOPROTEINS, HDL; TOLL-LIKE RECEPTOR 2;

EID: 84886237065     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.07.210     Document Type: Editorial

References (16)

1. S. Xu, S. Ogura, J. Chen, P.J. Little, J. Moss, and P. Liu LOX-1 in atherosclerosis: biological functions and pharmacological modifiers Cell Mol Life Sci 70 2013 Aug 2859 2872
2. T. Speer, L. Rohrer, and P. Blyszczuk Abnormal high-density lipoprotein induces endothelial dysfunction via activation of toll-like receptor-2 Immunity 38 2013 754 768
3. A. Tran-Dinh, D. Diallo, and S. Delbosc HDL and endothelial protection Br J Pharmacol 169 2013 493 511
4. H.C. Prosser, M.K. Ng, and C.A. Bursill The role of cholesterol efflux in mechanisms of endothelial protection by HDL Curr Opin Lipidol 23 2012 182 189
5. C. Besler, K. Heinrich, and L. Rohrer Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease J Clin Invest 121 2011 2693 2708
6. B. Pan, B. Yu, and H. Ren High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair Free Radic Biol Med 60 2013 272 281
7. A. Pirillo, P. Uboldi, C. Bolego, H. Kuhn, and A.L. Catapano The 15-lipoxygenase-modified high density lipoproteins 3 fail to inhibit the TNF-alpha-induced inflammatory response in human endothelial cells J Immunol 181 2008 2821 2830
8. A. Pirillo, P. Uboldi, N. Ferri, A. Corsini, H. Kuhn, and A.L. Catapano Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins Biochem Biophys Res Commun 428 2012 230 233
9. J.H. Lee, J.H. Joo, and J. Kim Interaction of NADPH oxidase 1 with toll-like receptor 2 induces migration of smooth muscle cells Cardiovasc Res 99 2013 Aug 1 483 493
10. P. Libby, A.H. Lichtman, and G.K. Hansson Immune effector mechanisms implicated in atherosclerosis: from mice to humans Immunity 38 2013 1092 1104
11. A.E. Mullick, K. Soldau, W.B. Kiosses, T.A. Bell III, P.S. Tobias, and L.K. Curtiss Increased endothelial expression of toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events J Exp Med 205 2008 373 383
12. A.E. Mullick, P.S. Tobias, and L.K. Curtiss Modulation of atherosclerosis in mice by toll-like receptor 2 J Clin Invest 115 2005 3149 3156
13. K.E. Kypreos, S. Gkizas, L.S. Rallidis, and I. Karagiannides HDL particle functionality as a primary pharmacological target for HDL-based therapies Biochem Pharmacol 85 2013 1575 1578
14. K. Kotani, N. Sakane, and M. Ueda Oxidized high-density lipoprotein is associated with increased plasma glucose in non-diabetic dyslipidemic subjects Clin Chim Acta 414 2012 125 129
15. B. Pan, Y. Ma, and H. Ren Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression PLoS One 7 2012 e48530
16. P.J. Patel, A.V. Khera, R.L. Wilensky, and D.J. Rader Anti-oxidative and cholesterol efflux capacities of high-density lipoprotein are reduced in ischaemic cardiomyopathy Eur J Heart Fail 2013 10.1093/eurjhf/hft084