Classification of polycyclic aromatic hydrocarbons based on mutagenicity in lung tissue through DNA microarray

Environmental Toxicology

Volumn 28, Issue 11, 2013, Pages 652-659

  Hirano, Minoru ^a   Tanaka, Shiho ^a   Asami, Osamu ^a  

^a Rd Management Section   (Japan)

Author keywords

Cancer; Cytochrome P450; DNA damage; DNA microarray; Lung; Metabolic activation; Mutagenicity; P53; PAH; Polycyclic aromatic hydrocarbon

Indexed keywords

CANCER; CYTOCHROME P450; DNA DAMAGES; DNA MICRO-ARRAY; LUNG; METABOLIC ACTIVATION; MUTAGENICITY; P53;

BIOLOGICAL ORGANS; CHEMICAL ACTIVATION; DISEASES; DNA; METABOLISM; POLYCYCLIC AROMATIC HYDROCARBONS; PYRENE; TISSUE;

GENE EXPRESSION;

1 NITROPYRENE; 1,8 DINITROPYRENE; ALPHA NAPHTHOFLAVONE; BENZO[A]PYRENE; CYTOCHROME P450 1B1; DNA; PIFITHRIN ALPHA; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; UNCLASSIFIED DRUG;

ASTHMA; CLASSIFICATION; DNA; GENE EXPRESSION; GENOME; GENOTOXICITY; HEALTH RISK; INHIBITION; INHIBITOR; MUTAGENICITY; PAH; POLLUTION EXPOSURE; PUBLIC HEALTH;

ARTICLE; CLASSIFICATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; DNA MICROARRAY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG PARENCHYMA; METABOLIC ACTIVATION; MUTAGENICITY; NUCLEOTIDE SEQUENCE; POLLUTANT; PRIORITY JOURNAL; UPREGULATION; XENOBIOTIC METABOLISM;

CANCER; CYTOCHROME P450; DNA DAMAGE; DNA MICROARRAY; LUNG; METABOLIC ACTIVATION; MUTAGENICITY; P53; PAH; POLYCYCLIC AROMATIC HYDROCARBON;

ARYL HYDROCARBON HYDROXYLASES; BENZOFLAVONES; BENZOTHIAZOLES; CELL LINE; DNA DAMAGE; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENES, P53; HUMANS; LUNG; MUTAGENICITY TESTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYCYCLIC HYDROCARBONS, AROMATIC; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; TOLUENE;

EID: 84886234497     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20761     Document Type: Article

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