-
1
-
-
34247876974
-
Clinical pharmacodynamics & pharmacokinetics
-
(eds R.A. Helms and D.J. Quan), Lippincott Williams Wilkins, Philadelphia, PA
-
Meibohm, B., and Evans, W.E. (2006) Clinical pharmacodynamics & pharmacokinetics, in Textbook of Therapeutics: Drug and Disease Management (eds R.A. Helms and D.J. Quan), Lippincott Williams Wilkins, Philadelphia, PA, pp. 1-30.
-
(2006)
Textbook of Therapeutics: Drug and Disease Management
, pp. 1-30
-
-
Meibohm, B.1
Evans, W.E.2
-
2
-
-
4344634877
-
Pharmacokinetic aspects of biotechnology products
-
Tang, L., Persky, A.M., Hochhaus, G., and Meibohm, B. (2004) Pharmacokinetic aspects of biotechnology products . J. Pharm. Sci., 93, 2184-2204 .
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 2184-2204
-
-
Tang, L.1
Persky, A.M.2
Hochhaus, G.3
Meibohm, B.4
-
3
-
-
0037364162
-
ADMET in silico modelling: towards prediction paradise?
-
van de Waterbeemd, H., and Gifford, E. (2003) ADMET in silico modelling: towards prediction paradise? Nat. Rev. Drug Discov., 2, 192-204 .
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 192-204
-
-
van de Waterbeemd, H.1
Gifford, E.2
-
4
-
-
84889822280
-
Pharmacokinetics of peptides and proteins
-
(ed. B. Meibohm), Wiley-VCH Verlag GmbH, Weinheim
-
Tang, L., and Meibohm, B. (2006) Pharmacokinetics of peptides and proteins, in Pharmacokinetics and Pharmacodynamics of Biotech Drugs (ed. B. Meibohm), Wiley-VCH Verlag GmbH, Weinheim, pp. 17-44 .
-
(2006)
Pharmacokinetics and Pharmacodynamics of Biotech Drugs
, pp. 17-44
-
-
Tang, L.1
Meibohm, B.2
-
5
-
-
33846600867
-
Paving the critical path: how can clinical pharmacology help achieve the vision?
-
Lesko, L.J. (2007) Paving the critical path: how can clinical pharmacology help achieve the vision? Clin. Pharmacol. Ther., 81, 170-177 .
-
(2007)
Clin. Pharmacol. Ther.
, vol.81
, pp. 170-177
-
-
Lesko, L.J.1
-
6
-
-
0036144662
-
Pharmacokinetic/pharmacodynamic studies in drug product development
-
Meibohm, B., and Derendorf, H. (2002) Pharmacokinetic/pharmacodynamic studies in drug product development . J. Pharm. Sci., 91, 18-31 .
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 18-31
-
-
Meibohm, B.1
Derendorf, H.2
-
7
-
-
77950295526
-
The current role of model-based drug development
-
Suryawanshi, S., Zhang, L., Pfi ster, M., and Meibohm, B. (2010) The current role of model-based drug development . Expert Opin. Drug Discov., 5, 311-321 .
-
(2010)
Expert Opin. Drug Discov.
, vol.5
, pp. 311-321
-
-
Suryawanshi, S.1
Zhang, L.2
Pfister, M.3
Meibohm, B.4
-
8
-
-
0035409904
-
IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
-
Herbst, R.S., Kim, E.S., and Harari, P.M. (2001) IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer . Expert Opin. Biol. Ther., 1, 719-732 .
-
(2001)
Expert Opin. Biol. Ther.
, vol.1
, pp. 719-732
-
-
Herbst, R.S.1
Kim, E.S.2
Harari, P.M.3
-
9
-
-
0141997761
-
Emerging trends in oral delivery of peptide and protein drugs
-
Mahato, R.I., Narang, A.S., Thoma, L., and Miller, D.D. (2003) Emerging trends in oral delivery of peptide and protein drugs . Crit. Rev. Ther. Drug Carrier Syst., 20, 153-214 .
-
(2003)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.20
, pp. 153-214
-
-
Mahato, R.I.1
Narang, A.S.2
Thoma, L.3
Miller, D.D.4
-
10
-
-
0038350680
-
Oral peptide and protein delivery: unfulfi lled promises?
-
Shen, W.C. (2003) Oral peptide and protein delivery: unfulfi lled promises? Drug Discov. Today, 8, 607-608 .
-
(2003)
Drug Discov. Today
, vol.8
, pp. 607-608
-
-
Shen, W.C.1
-
11
-
-
0036779424
-
Protein drug oral delivery: the recent progress
-
Lee, H.J. (2002) Protein drug oral delivery: the recent progress . Arch. Pharm. Res., 25, 572-584 .
-
(2002)
Arch. Pharm. Res.
, vol.25
, pp. 572-584
-
-
Lee, H.J.1
-
12
-
-
39149115174
-
Pharmacokinetics and pharmacodynamics of peptides and proteins
-
(eds D.J.A. Crommelin, R.D. Sindelar, and B. Meibohm), Informa Healthcare, New York
-
Meibohm, B., and Braeckman, R.A. (2007) Pharmacokinetics and pharmacodynamics of peptides and proteins, in Pharmaceutical Biotechnology: Concepts and Applications (eds D.J.A. Crommelin, R.D. Sindelar, and B. Meibohm), Informa Healthcare, New York, pp. 95-123 .
-
(2007)
Pharmaceutical Biotechnology: Concepts and Applications
, pp. 95-123
-
-
Meibohm, B.1
Braeckman, R.A.2
-
14
-
-
33750690230
-
In vivo diffusion of immunoglobulin G in muscle: effects of binding, solute exclusion, and lymphatic removal
-
Flessner, M.F., Lofthouse, J., and Zakaria, R. (1997) In vivo diffusion of immunoglobulin G in muscle: effects of binding, solute exclusion, and lymphatic removal . A m. J. Physiol., 273, H2783-H2793 .
-
(1997)
A m. J. Physiol.
, vol.273
-
-
Flessner, M.F.1
Lofthouse, J.2
Zakaria, R.3
-
15
-
-
33749331350
-
A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles
-
Reddy, S.T., Berk, D.A., Jain, R.K., and Swartz, M.A. (2006) A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles . J. Appl. Physiol., 101, 1162-1169 .
-
(2006)
J. Appl. Physiol.
, vol.101
, pp. 1162-1169
-
-
Reddy, S.T.1
Berk, D.A.2
Jain, R.K.3
Swartz, M.A.4
-
16
-
-
2842572177
-
Peptide, peptoid, and protein pharmacokinetics/ pharmacodynamics
-
(eds P. Garzone, W. Colburn, and M. Mokotoff), Harvey Whitney Books, Cincinnati, OH.
-
Colburn, W. (1991) Peptide, peptoid, and protein pharmacokinetics/ pharmacodynamics, in Petides, Peptoids, and Proteins, vol. 3, (eds P. Garzone, W. Colburn, and M. Mokotoff), Harvey Whitney Books, Cincinnati, OH, pp. 94-115 .
-
(1991)
Petides, Peptoids, and Proteins
, vol.3
, pp. 94-115
-
-
Colburn, W.1
-
17
-
-
0036141796
-
Pharmacokinetics and pharmacodynamics of AJW200, a humanized monoclonal antibody to von Willebrand factor, in monkeys
-
Kageyama, S., Yamamoto, H., Nakazawa, H., Matsushita, J., Kouyama, T., Gonsho, A., Ikeda, Y., and Yoshimoto, R. (2002) Pharmacokinetics and pharmacodynamics of AJW200, a humanized monoclonal antibody to von Willebrand factor, in monkeys . Arterioscler. Thromb. Vasc. Biol., 22, 187-192 .
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 187-192
-
-
Kageyama, S.1
Yamamoto, H.2
Nakazawa, H.3
Matsushita, J.4
Kouyama, T.5
Gonsho, A.6
Ikeda, Y.7
Yoshimot, R.8
-
18
-
-
84889856889
-
Limitations of noncompartmental pharmacokinetic analysis of biotech drugs
-
(ed. B. Meibohm), Wiley-VCH Verlag GmbH, Weinheim
-
Straughn, A.B. (2006) Limitations of noncompartmental pharmacokinetic analysis of biotech drugs, in Pharmacokinetics and Pharmacodynamics of Biotech Drugs (ed. B. Meibohm), Wiley-VCH Verlag GmbH, Weinheim, pp. 181-188 .
-
(2006)
Pharmacokinetics and Pharmacodynamics of Biotech Drugs
, pp. 181-188
-
-
Straughn, A.B.1
-
19
-
-
0019974468
-
Noncompartmental determination of the steady-state volume of distribution for any mode of administration
-
Perrier, D., and Mayersohn, M. (1982) Noncompartmental determination of the steady-state volume of distribution for any mode of administration . J. Pharm. Sci., 71, 372-373 .
-
(1982)
J. Pharm. Sci.
, vol.71
, pp. 372-373
-
-
Perrier, D.1
Mayersohn, M.2
-
20
-
-
0019945174
-
Model-independent steady-state volume of distribution
-
Straughn, A.B. (1982) Model-independent steady-state volume of distribution . J. Pharm. Sci., 71, 597-598 .
-
(1982)
J. Pharm. Sci.
, vol.71
, pp. 597-598
-
-
Straughn, A.B.1
-
21
-
-
0034799334
-
Structural determinants of glomerular permeability
-
Deen, W.M., Lazzara, M.J., and Myers, B.D. (2001) Structural determinants of glomerular permeability . Am. J. Physiol. Renal Physiol., 281, F579-F596 .
-
(2001)
Am. J. Physiol. Renal Physiol.
, vol.281
-
-
Deen, W.M.1
Lazzara, M.J.2
Myers, B.D.3
-
22
-
-
67650752891
-
Pharmacokinetics and pharmacodynamics of biotech drugs
-
(eds R. Muller and O. Kayser), Wiley-VCH Verlag GmbH, Weinheim
-
Meibohm, B., and Derendorf, H. (2004) Pharmacokinetics and pharmacodynamics of biotech drugs, in Pharmaceutical Biotechnology: Drug Discovery and Clinical Appications (eds R. Muller and O. Kayser), Wiley-VCH Verlag GmbH, Weinheim, pp. 147-172 .
-
(2004)
Pharmaceutical Biotechnology: Drug Discovery and Clinical Appications
, pp. 147-172
-
-
Meibohm, B.1
Derendorf, H.2
-
23
-
-
33646901012
-
Target-mediated drug disposition and dynamics
-
Mager, D.E. (2006) Target-mediated drug disposition and dynamics . Biochem. Pharmacol., 72, 1-10 .
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 1-10
-
-
Mager, D.E.1
-
24
-
-
0028013741
-
Nonlinear pharmacokinetics of recombinant human macrophage colony-stimulating factor (M-CSF) in rats
-
Bauer, R.J., Gibbons, J.A., Bell, D.P., Luo, Z.P., and Young, J.D. (1994) Nonlinear pharmacokinetics of recombinant human macrophage colony-stimulating factor (M-CSF) in rats . J. Pharmacol. Exp. Ther., 268, 152-158 .
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 152-158
-
-
Bauer, R.J.1
Gibbons, J.A.2
Bell, D.P.3
Luo, Z.P.4
Young, J.D.5
-
25
-
-
34548229364
-
FcRn: the neonatal Fc receptor comes of age
-
Roopenian, D.C., and Akilesh, S. (2007) FcRn: the neonatal Fc receptor comes of age . Nat. Rev. Immunol., 7, 715-725 .
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 715-725
-
-
Roopenian, D.C.1
Akilesh, S.2
-
26
-
-
54249138516
-
Monoclonal antibody pharmacokinetics and pharmacodynamics
-
Wang, W., Wang, E.Q., and Balthasar, J.P. (2008) Monoclonal antibody pharmacokinetics and pharmacodynamics . Clin. Pharmacol. Ther., 84, 548-558 .
-
(2008)
Clin. Pharmacol. Ther.
, vol.84
, pp. 548-558
-
-
Wang, W.1
Wang, E.Q.2
Balthasar, J.P.3
-
27
-
-
77956388219
-
Population pharmacokinetics of therapeutic monoclonal antibodies
-
Dirks, N.L., and Meibohm, B. (2010) Population pharmacokinetics of therapeutic monoclonal antibodies . Clin. Pharmacokinet., 49, 633-659 .
-
(2010)
Clin. Pharmacokinet.
, vol.49
, pp. 633-659
-
-
Dirks, N.L.1
Meibohm, B.2
-
28
-
-
33846050957
-
Kinetics of FcRn-mediated recycling of IgG and albumin in human: pathophysiology and therapeutic implications using a simplifi ed mechanism-based model
-
Kim, J., Hayton, W.L., Robinson, J.M., and Anderson, C.L. (2007) Kinetics of FcRn-mediated recycling of IgG and albumin in human: pathophysiology and therapeutic implications using a simplifi ed mechanism-based model . Clin. Immunol., 122, 146-155 .
-
(2007)
Clin. Immunol.
, vol.122
, pp. 146-155
-
-
Kim, J.1
Hayton, W.L.2
Robinson, J.M.3
Anderson, C.L.4
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