Quantitative Structure-Permeability Relationships

Comparative Pharmacokinetics: Principles, Techniques, and Applications: Second Edition

Volumn , Issue , 2011, Pages 27-38

  Xia, Xin Rui ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Applicability domain, theoretical region in chemical space model descriptors and modeled response; Drug molecule transport, essential biological process governing pharmacokinetic properties; Molecule's ability to pass through a membrane, its permeability; Primary barrier to absorption stratum corneum, a lipid membrane; QSPeR analyses of gastrointestinal permeability; QSPeR analysis, power of using mathematical models probing interactions between drugs and biological systems; QSPeR approach, drug discovery and occupational and environmental risk assessment; QSPeR modeling, correlation structural or chemical property descriptors of compounds with membrane permeability of compounds; Quantitative structure permeability relationships with Xin Rui Xia; Statistical method, establishing quantitative relationship collecting data and molecular descriptors

Indexed keywords

EID: 84886127482     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470959916.ch3     Document Type: Chapter

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