A perfusion procedure for imaging of the mouse cerebral vasculature by X-ray micro-CT

Journal of Neuroscience Methods

Volumn 221, Issue , 2014, Pages 70-77

  Ghanavati, Sahar ^a,b   Yu, Lisa X ^b   Lerch, Jason P ^a,b   Sled, John G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

3D imaging; Brain vasculature; Casting; Contrast agent; Micro CT; Mouse; Perfusion

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN CORTEX; BRAIN PERFUSION; BRAIN RADIOGRAPHY; CEREBELLUM; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HISTOLOGY; HYPOTHALAMUS; IMAGE QUALITY; MESENCEPHALON; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; THALAMUS;

3D IMAGING; BRAIN VASCULATURE; CASTING; CONTRAST AGENT; MICRO-CT; MOUSE; PERFUSION;

ANIMALS; BRAIN; CONTRAST MEDIA; HISTOLOGICAL TECHNIQUES; IMAGING, THREE-DIMENSIONAL; MICE; MICE, INBRED C57BL; PERFUSION; X-RAY MICROTOMOGRAPHY;

EID: 84885986224     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2013.09.002     Document Type: Article

References (31)

1. Arras M., Autenried P., Rettich A., Spaeni D., Rulicke T. Optimization of intraperitoneal injection anesthesia in mice: Drugs, dosages, adverse effects, and anesthesia depth. Comparative Medicine 2001, 51(5):443-456.
2. Beckmann N. High resolution magnetic resonance angiography non-invasively reveals mouse strain differences in the cerebrovascular anatomy in vivo. Magnetic Resonance in Medicine 2000, 44:252-258.
3. Bentley M.D., Ortiz M.C., Ritman E.L., Romero J.C. The use of microcomputed tomography to study microvasculature in small rodents. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2002, 282(5):R1267-R1279.
4. Burton A.C. Physiology and biophysics of the circulation 1972, Year Book Medical Publishers, Chicago, IL. 2nd ed.
5. Chugh B.P., Lerch J.P., Yu L.X., Pienkowski M., Harrison R.V., Henkelman R.M., et al. Measurement of cerebral blood volume in mouse brain regions using micro-computed tomography. Neuroimage 2009, 47(4):1312-1318.
6. Chutkow W.A., Pu J., Wheeler M.T., Wada T., Makielski J.C., Burant C.F., et al. Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels. Journal of Clinical Investigation 2002, 110(2):203-208.
7. Cortell S. Silicone rubber for renal tubular injection. Journal of Applied Physiology 1969, 26(1):158-159.
8. Cruise G.M., Rivera E.A., Jones R.M., Vestal M., Virmani R., Ding Y.-H., et al. A comparison of experimental aneurysm occlusion determination by angiography, scanning electron microscopy, MICROFIL perfusion, and histology. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2009, 91(2):669-678.
9. Daneyemez M. Microangiographic changes following cerebral contusion in rats. Neuroscience 1999, 92(2):783-790.
10. Dorr A.E., Lerch J.P., Spring S., Kabani N., Henkelman R.M. High resolution three-dimensional brain atlas using an average magnetic resonance image of 40 adult C57Bl/6J mice. NeuroImage 2008, 42(1):60-69.
11. Faraci F.M., Modrick M.L., Lynch C.M., Didion L.A., Fegan P.E., Didion S.P. Selective cerebral vascular dysfunction in Mn-SOD-deficient mice. Journal of Applied Physiology 2006, 100(6):2089-2093.
12. Heinzer S., Krucker T., Stampanoni M., Abela R., Meyer E.P., Schuler A., et al. Hierarchical microimaging for multiscale analysis of large vascular networks. Neuroimage 2006, 32(2):626-636.
13. Holdsworth D.W., Thornton M.M. Micro-CT in small animal and specimen imaging. Trends in Biotechnology 2002, 20(8):S34-S39.
14. Jorgensen S.M., Demirkaya O., Ritman E.L. Three-dimensional imaging of vasculature and parenchyma in intact rodent organs with X-ray micro-CT. American Journal of Physiology-Heart and Circulatory Physiology 1998, 275(3):H1103-H1114.
15. Kidoguchi K., Tamaki M., Mizobe T., Koyama J., Kondoh T., Kohmura E., et al. In vivo X-ray angiography in the mouse brain using synchrotron radiation. Stroke 2006, 37(7):1856-1861.
16. Krucker T., Lang A., Meyer E.P. New polyurethane-based material for vascular corrosion casting with improved physical and imaging characteristics. Microscopy Research and Technique 2006, 69(2):138-147.
17. Li J.K. Dynamics of the vascular system, vol. 1 2004, World Scientific Publishing Company, New Jersey, USA.
18. Marxen M., Sled J.G., Yu L.X., Paget C., Henkelman R.M. Comparing microsphere deposition and flow modeling in 3D vascular trees. American Journal of Physiology-Heart and Circulatory Physiology 2006, 291(5):H2136-H2141.
19. Marxen M., Thornton M.M., Chiarot C.B., Klement G., Koprivnikar J., Sled J.G., et al. MicroCT scanner performance and considerations for vascular specimen imaging. Medical Physics 2004, 31:305.
20. Nordsletten D.A., Blackett S., Bentley M.D., Ritman E.L., Smith N.P. Structural morphology of renal vasculature. American Journal of Physiology-Heart and Circulatory Physiology 2006, 291(1):H296-H309.
21. Pathak A.P., Jones M., Zhang J. New techniques for 3D, high-resolution, whole brain mapping of murine vasculature. Proceedings of International Society for Magnetic Resonance in Medicine, vol. 16 2008, 284.
22. Rennie M.Y., Detmar J., Whiteley K.J., Yang J., Jurisicova A., Adamson S.L., et al. Vessel tortuousity and reduced vascularization in the fetoplacental arterial tree after maternal exposure to polycyclic aromatic hydrocarbons. American Journal of Physiology-Heart and Circulatory Physiology 2010, 300:H675-H684.
23. Rennie M.Y., Whiteley K.J., Kulandavelu S., Adamson S.L., Sled J.G. 3D visualisation and quantification by microcomputed tomography of late gestational changes in the arterial and venous feto-placental vasculature of the mouse. Placenta 2007, 28(8):833-840.
24. Scheel P., Ruge C., Petruch U.R., Schoning M. Color duplex measurement of cerebral blood flow volume in healthy adults. Stroke 2000, 31(1):147-150.
25. Scremin O.U., Holschneider D.P. The mouse nervous system. Vascular supply 2011, Academic Press, San Diego, USA. C. Watson, G. Paxinos, L. Puelles (Eds.).
26. van den Wijngaard J.P.H.M., Schwarz J.C.V., van Horssen P., van Lier M.G.J.T.B., Dobbe J.G.G., Spaan J.A.E., et al. 3D imaging of vascular networks for biophysical modeling of perfusion distribution within the heart. Journal of Biomechanics 2013, 46(2):229-239.
27. Vasquez S.X., Gao F., Su F., Grijalva V., Pope J., Martin B., et al. Optimization of microCT imaging and blood vessel diameter quantitation of preclinical specimen vasculature with radiopaque polymer injection medium. PloS ONE 2011, 6(4):e19099.
28. Walker E.J., Shen F., Young W.L., Su H. Cerebrovascular casting of the adult mouse for 3D imaging and morphological analysis. Journal of Visualized Experiments 2011, 57:e2958.
29. Wellons J.C., Sheng H., Laskowitz D.T., Mackensen G.B., Pearlstein R.D., Warner D.S. A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. Brain Research 2000, 868(1):14-21.
30. Yang J., Yu L.X., Rennie M.Y., Sled J.G., Henkelman R.M. Comparative structural and hemodynamic analysis of vascular trees. American Journal of Physiology-Heart and Circulatory Physiology 2010, 298(4):H1249-H1259.
31. Young S.W., Hollenberg N.K., Kazam E., Berkowitz D.M., Hainen R., Sandor T., et al. Resting host and tumor perfusion as determinants of tumor vascular responses to norepinephrine. Cancer Research 1979, 39(6 Part 1):1898-1903.