-
1
-
-
31444432477
-
Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
-
doi: 10.1007/s00125-005-0045-y
-
Asghar Z, Yau D, Chan F, Leroith D, Chan CB, et al. (2006) Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes. Diabetologia 49: 90-99. doi:10.1007/s00125-005-0045-y. PubMed: 16362284.
-
(2006)
Diabetologia
, vol.49
, pp. 90-99
-
-
Asghar, Z.1
Yau, D.2
Chan, F.3
Leroith, D.4
Chan, C.B.5
-
2
-
-
0035820470
-
Insulin secretion and insulin sensitivity in relation to glucose tolerance in a group of subjects at a high risk for type 2 diabetes mellitus
-
doi: 10.1016/S0025-7753(01)71882-9
-
Conget I, Fernandez Real JM, Costa A, Casamitjana R, Ricart W, (2001) Insulin secretion and insulin sensitivity in relation to glucose tolerance in a group of subjects at a high risk for type 2 diabetes mellitus. Med Clin (Barc) 116: 491-492. doi:10.1016/S0025-7753(01)71882-9.
-
(2001)
Med Clin (Barc)
, vol.116
, pp. 491-492
-
-
Conget, I.1
Fernandez Real, J.M.2
Costa, A.3
Casamitjana, R.4
Ricart, W.5
-
3
-
-
0033854659
-
Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes
-
doi: 10.2337/diabetes.49.8.1334
-
Hollingdal M, Juhl CB, Pincus SM, Sturis J, Veldhuis JD, et al. (2000) Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. Diabetes 49: 1334-1340. doi:10.2337/diabetes.49.8.1334. PubMed: 10923634.
-
(2000)
Diabetes
, vol.49
, pp. 1334-1340
-
-
Hollingdal, M.1
Juhl, C.B.2
Pincus, S.M.3
Sturis, J.4
Veldhuis, J.D.5
-
4
-
-
3242718780
-
Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose
-
doi: 10.1152/ajpendo.00426.2003
-
Khaldi MZ, Guiot Y, Gilon P, Henquin JC, Jonas JC, (2004) Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose. Am J Physiol Endocrinol Metab 287: E207-E217. doi:10.1152/ajpendo.00426.2003. PubMed: 15100093.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Khaldi, M.Z.1
Guiot, Y.2
Gilon, P.3
Henquin, J.C.4
Jonas, J.C.5
-
5
-
-
59449084679
-
Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations
-
doi: 10.1007/s00125-008-1245-z
-
Bensellam M, Van Lommel L, Overbergh L, Schuit FC, Jonas JC, (2009) Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations. Diabetologia 52: 463-476. doi:10.1007/s00125-008-1245-z. PubMed: 19165461.
-
(2009)
Diabetologia
, vol.52
, pp. 463-476
-
-
Bensellam, M.1
Van Lommel, L.2
Overbergh, L.3
Schuit, F.C.4
Jonas, J.C.5
-
6
-
-
0041833733
-
Pancreatic beta-cell loss and preservation in type 2 diabetes
-
doi: 10.1016/S0149-2918(03)80241-2
-
Buchanan TA, (2003) Pancreatic beta-cell loss and preservation in type 2 diabetes. Clin Ther 25 (Suppl B):: B32-B46. doi:10.1016/S0149-2918(03)80241-2. PubMed: 14553865.
-
(2003)
Clin Ther
, vol.25
, Issue.SUPPL. B
-
-
Buchanan, T.A.1
-
7
-
-
54949157651
-
Beta-cell failure as a complication of diabetes
-
doi: 10.1007/s11154-008-9101-5
-
Chang-Chen KJ, Mullur R, Bernal-Mizrachi E, (2008) Beta-cell failure as a complication of diabetes. Rev Endocr Metab Disord 9: 329-343. doi:10.1007/s11154-008-9101-5. PubMed: 18777097.
-
(2008)
Rev Endocr Metab Disord
, vol.9
, pp. 329-343
-
-
Chang-Chen, K.J.1
Mullur, R.2
Bernal-Mizrachi, E.3
-
8
-
-
70350330155
-
Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes
-
doi: 10.1111/j.1463-1326.2009.01113.x
-
Weir GC, Marselli L, Marchetti P, Katsuta H, Jung MH, et al. (2009) Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes. Diabetes Obes Metab 11 (Suppl 4):: 82-90. doi:10.1111/j.1463-1326.2009.01113.x. PubMed: 19817791.
-
(2009)
Diabetes Obes Metab
, vol.11
, Issue.SUPPL. 4
, pp. 82-90
-
-
Weir, G.C.1
Marselli, L.2
Marchetti, P.3
Katsuta, H.4
Jung, M.H.5
-
9
-
-
34848901678
-
Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway
-
doi: 10.1016/j.neuint.2007.04.021
-
Liu J, Yin F, Zheng X, Jing J, Hu Y, (2007) Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway. Neurochem Int 51: 361-369. doi:10.1016/j.neuint.2007.04.021. PubMed: 17629357.
-
(2007)
Neurochem Int
, vol.51
, pp. 361-369
-
-
Liu, J.1
Yin, F.2
Zheng, X.3
Jing, J.4
Hu, Y.5
-
10
-
-
33750066662
-
Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells
-
doi: 10.1016/j.ijdevneu.2006.08.009
-
Liu J, Zheng X, Yin F, Hu Y, Guo L, et al. (2006) Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells. Int J Dev Neurosci 24: 419-424. doi:10.1016/j.ijdevneu.2006.08.009. PubMed: 17045447.
-
(2006)
Int J Dev Neurosci
, vol.24
, pp. 419-424
-
-
Liu, J.1
Zheng, X.2
Yin, F.3
Hu, Y.4
Guo, L.5
-
11
-
-
65349142455
-
Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway
-
doi: 10.1038/aps.2008.25
-
Liu JH, Yin F, Guo LX, Deng XH, Hu YH, (2009) Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway. Acta Pharmacol Sin 30: 159-165. doi:10.1038/aps.2008.25. PubMed: 19151742.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 159-165
-
-
Liu, J.H.1
Yin, F.2
Guo, L.X.3
Deng, X.H.4
Hu, Y.H.5
-
12
-
-
77952039825
-
GLP-1 receptor plays a critical role in geniposide-induced expression of heme oxygenase-1 in PC12 cells
-
PubMed: 20364157
-
Yin F, Liu JH, Zheng XX, Guo LX, (2011) GLP-1 receptor plays a critical role in geniposide-induced expression of heme oxygenase-1 in PC12 cells. Acta Pharmacol Sin 31: 540-545. PubMed: 20364157.
-
(2011)
Acta Pharmacol Sin
, vol.31
, pp. 540-545
-
-
Yin, F.1
Liu, J.H.2
Zheng, X.X.3
Guo, L.X.4
-
13
-
-
78249260599
-
Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2-signaling to enhance the antioxidant capacity in primary hippocampal neurons
-
doi: 10.1248/bpb.33.1841
-
Yin F, Liu J, Zheng X, Guo L, Xiao H, (2010) Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2-signaling to enhance the antioxidant capacity in primary hippocampal neurons. Biol Pharm Bull 33: 1841-1846. doi:10.1248/bpb.33.1841. PubMed: 21048309.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 1841-1846
-
-
Yin, F.1
Liu, J.2
Zheng, X.3
Guo, L.4
Xiao, H.5
-
14
-
-
84863133805
-
Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells
-
doi: 10.1038/aps.2011.146
-
Guo LX, Xia ZN, Gao X, Yin F, Liu JH, (2012) Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells. Acta Pharmacol Sin 33: 237-241. doi:10.1038/aps.2011.146. PubMed: 22101168.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 237-241
-
-
Guo, L.X.1
Xia, Z.N.2
Gao, X.3
Yin, F.4
Liu, J.H.5
-
15
-
-
84866053595
-
Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced beta-cell apoptosis
-
doi: 10.1016/j.tiv.2012.07.004
-
Liu J, Yin F, Xiao H, Guo L, Gao X, (2012) Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced beta-cell apoptosis. Toxicol Vitro 26: 1093-1097. doi:10.1016/j.tiv.2012.07.004.
-
(2012)
Toxicol Vitro
, vol.26
, pp. 1093-1097
-
-
Liu, J.1
Yin, F.2
Xiao, H.3
Guo, L.4
Gao, X.5
-
16
-
-
84886082180
-
Effect of geniposide on teh cytotoxicity of hIAPP in INS-1E cells
-
In press
-
Liu JH, Zhang YL, Liu ZX, Yin F, (2012) Effect of geniposide on teh cytotoxicity of hIAPP in INS-1E cells. Diabet Med (In press).
-
(2012)
Diabet Med
-
-
Liu, J.H.1
Zhang, Y.L.2
Liu, Z.X.3
Yin, F.4
-
17
-
-
33847386626
-
Pancreatic islets from hypothalamic obese rats maintain K+ATP channel-dependent but not -independent pathways on glucose-induced insulin release process
-
doi: 10.1385/ENDO:30:2:191
-
Grassiolli S, Bonfleur ML, Scomparin DX, de Freitas Mathias PC, (2006) Pancreatic islets from hypothalamic obese rats maintain K+ATP channel-dependent but not-independent pathways on glucose-induced insulin release process. Endocrine 30: 191-196. doi:10.1385/ENDO:30:2:191. PubMed: 17322578.
-
(2006)
Endocrine
, vol.30
, pp. 191-196
-
-
Grassiolli, S.1
Bonfleur, M.L.2
Scomparin, D.X.3
de Freitas Mathias, P.C.4
-
18
-
-
33747164550
-
Increased ATP-sensitive K+ channel expression during acute glucose deprivation
-
doi: 10.1016/j.bbrc.2006.07.170
-
Smith AJ, Partridge CJ, Asipu A, Mair LA, Hunter M, et al. (2006) Increased ATP-sensitive K+ channel expression during acute glucose deprivation. Biochem Biophys Res Commun 348: 1123-1131. doi:10.1016/j.bbrc.2006.07.170. PubMed: 16904639.
-
(2006)
Biochem Biophys Res Commun
, vol.348
, pp. 1123-1131
-
-
Smith, A.J.1
Partridge, C.J.2
Asipu, A.3
Mair, L.A.4
Hunter, M.5
-
19
-
-
33845971563
-
The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion
-
doi: 10.1074/jbc.M602606200
-
Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alárcon C, et al. (2006) The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. J Biol Chem 281: 35624-35632. doi:10.1074/jbc.M602606200. PubMed: 17001083.
-
(2006)
J Biol Chem
, vol.281
, pp. 35624-35632
-
-
Joseph, J.W.1
Jensen, M.V.2
Ilkayeva, O.3
Palmieri, F.4
Alárcon, C.5
-
20
-
-
66849113836
-
Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion
-
doi: 10.1152/ajpendo.90836.2008
-
Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, et al. (2009) Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab 296: E1354-E1362. doi:10.1152/ajpendo.90836.2008. PubMed: 19293334.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Heart, E.1
Cline, G.W.2
Collis, L.P.3
Pongratz, R.L.4
Gray, J.P.5
-
21
-
-
43049157727
-
Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential
-
doi: 10.1016/j.biocel.2007.11.015
-
Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, et al. (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40: 1522-1535. doi:10.1016/j.biocel.2007.11.015. PubMed: 18248766.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1522-1535
-
-
Spacek, T.1
Santorová, J.2
Zacharovová, K.3
Berková, Z.4
Hlavatá, L.5
-
22
-
-
33746847686
-
Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion
-
doi: 10.1074/jbc.M604350200
-
Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, et al. (2006) Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion. J Biol Chem 281: 22342-22351. doi:10.1074/jbc.M604350200. PubMed: 16740637.
-
(2006)
J Biol Chem
, vol.281
, pp. 22342-22351
-
-
Jensen, M.V.1
Joseph, J.W.2
Ilkayeva, O.3
Burgess, S.4
Lu, D.5
-
23
-
-
0029932643
-
New insights into pancreatic beta-cell metabolic signaling in insulin secretion
-
doi: 10.1530/eje.0.1340272
-
Prentki M, (1996) New insights into pancreatic beta-cell metabolic signaling in insulin secretion. Eur J Endocrinol 134: 272-286. doi:10.1530/eje.0.1340272. PubMed: 8616523.
-
(1996)
Eur J Endocrinol
, vol.134
, pp. 272-286
-
-
Prentki, M.1
-
24
-
-
0030810982
-
Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells
-
doi: 10.1074/jbc.272.30.18572
-
Schuit F, De Vos A, Farfari S, Moens K, Pipeleers D, et al. (1997) Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells. J Biol Chem 272: 18572-18579. doi:10.1074/jbc.272.30.18572. PubMed: 9228023.
-
(1997)
J Biol Chem
, vol.272
, pp. 18572-18579
-
-
Schuit, F.1
De Vos, A.2
Farfari, S.3
Moens, K.4
Pipeleers, D.5
-
25
-
-
0029014451
-
Influence of glucose on pyruvate carboxylase expression in pancreatic islets
-
doi: 10.1006/abbi.1995.1274
-
MacDonald MJ, (1995) Influence of glucose on pyruvate carboxylase expression in pancreatic islets. Arch Biochem Biophys 319: 128-132. doi:10.1006/abbi.1995.1274. PubMed: 7771776.
-
(1995)
Arch Biochem Biophys
, vol.319
, pp. 128-132
-
-
MacDonald, M.J.1
-
26
-
-
0027205593
-
Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets
-
doi: 10.1006/abbi.1993.1413
-
MacDonald MJ, (1993) Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets. Arch Biochem Biophys 305: 205-214. doi:10.1006/abbi.1993.1413. PubMed: 8373157.
-
(1993)
Arch Biochem Biophys
, vol.305
, pp. 205-214
-
-
MacDonald, M.J.1
-
27
-
-
0034602141
-
Glutamate is not a messenger in insulin secretion
-
doi: 10.1074/jbc.C000411200
-
MacDonald MJ, Fahien LA, (2000) Glutamate is not a messenger in insulin secretion. J Biol Chem 275: 34025-34027. doi:10.1074/jbc.C000411200. PubMed: 10967090.
-
(2000)
J Biol Chem
, vol.275
, pp. 34025-34027
-
-
MacDonald, M.J.1
Fahien, L.A.2
-
28
-
-
0029097424
-
Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion
-
PubMed: 7650022
-
MacDonald MJ, (1995) Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion. J Biol Chem 270: 20051-20058. PubMed: 7650022.
-
(1995)
J Biol Chem
, vol.270
, pp. 20051-20058
-
-
MacDonald, M.J.1
-
29
-
-
33644688772
-
Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection
-
doi: 10.2337/diabetes.54.11.3065
-
Koster JC, Permutt MA, Nichols CG, (2005) Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection. Diabetes 54: 3065-3072. doi:10.2337/diabetes.54.11.3065. PubMed: 16249427.
-
(2005)
Diabetes
, vol.54
, pp. 3065-3072
-
-
Koster, J.C.1
Permutt, M.A.2
Nichols, C.G.3
-
30
-
-
33845934827
-
Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet
-
PubMed: 17093947
-
Fex M, Nitert MD, Wierup N, Sundler F, Ling C, et al. (2007) Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet. Diabetologia 50: 74-83. PubMed: 17093947.
-
(2007)
Diabetologia
, vol.50
, pp. 74-83
-
-
Fex, M.1
Nitert, M.D.2
Wierup, N.3
Sundler, F.4
Ling, C.5
-
31
-
-
33745817133
-
Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling
-
doi: 10.1007/s00125-006-0305-5
-
Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, et al. (2006) Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia 49: 2120-2130. doi:10.1007/s00125-006-0305-5. PubMed: 16868750.
-
(2006)
Diabetologia
, vol.49
, pp. 2120-2130
-
-
Nolan, C.J.1
Leahy, J.L.2
Delghingaro-Augusto, V.3
Moibi, J.4
Soni, K.5
-
32
-
-
43549108142
-
Glucolipotoxicity: fuel excess and beta-cell dysfunction
-
PubMed: 18048763
-
Poitout V, Robertson RP, (2008) Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr Rev 29: 351-366. PubMed: 18048763.
-
(2008)
Endocr Rev
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
33
-
-
0038825044
-
Glucotoxicity and beta-cell failure in type 2 diabetes mellitus
-
PubMed: 12585335
-
Kaiser N, Leibowitz G, Nesher R, (2003) Glucotoxicity and beta-cell failure in type 2 diabetes mellitus. J Pediatr Endocrinol Metab 16: 5-22. PubMed: 12585335.
-
(2003)
J Pediatr Endocrinol Metab
, vol.16
, pp. 5-22
-
-
Kaiser, N.1
Leibowitz, G.2
Nesher, R.3
-
34
-
-
0035124998
-
beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes
-
doi: 10.2337/diabetes.50.2007.S113
-
Leibowitz G, Yuli M, Donath MY, Nesher R, Melloul D, et al. (2001) beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes. Diabetes 50 (Suppl 1):: S113-S117. doi:10.2337/diabetes.50.2007.S113. PubMed: 11272167.
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Leibowitz, G.1
Yuli, M.2
Donath, M.Y.3
Nesher, R.4
Melloul, D.5
-
35
-
-
57349097780
-
Metabolic cycling in control of glucose-stimulated insulin secretion
-
doi: 10.1152/ajpendo.90604.2008
-
Jensen MV, Joseph JW, Ronnebaum SM, Burgess SC, Sherry AD, et al. (2008) Metabolic cycling in control of glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab 295: E1287-E1297. doi:10.1152/ajpendo.90604.2008. PubMed: 18728221.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Jensen, M.V.1
Joseph, J.W.2
Ronnebaum, S.M.3
Burgess, S.C.4
Sherry, A.D.5
-
36
-
-
77952096424
-
Regulation of insulin secretion: role of mitochondrial signalling
-
doi: 10.1007/s00125-010-1685-0
-
Jitrapakdee S, Wutthisathapornchai A, Wallace JC, MacDonald MJ, (2010) Regulation of insulin secretion: role of mitochondrial signalling. Diabetologia 53: 1019-1032. doi:10.1007/s00125-010-1685-0. PubMed: 20225132.
-
(2010)
Diabetologia
, vol.53
, pp. 1019-1032
-
-
Jitrapakdee, S.1
Wutthisathapornchai, A.2
Wallace, J.C.3
MacDonald, M.J.4
-
37
-
-
33745105118
-
Anaplerotic molecules: current and future
-
doi: 10.1007/s10545-006-0320-1
-
Brunengraber H, Roe CR, (2006) Anaplerotic molecules: current and future. J Inherit Metab Dis 29: 327-331. doi:10.1007/s10545-006-0320-1. PubMed: 16763895.
-
(2006)
J Inherit Metab Dis
, vol.29
, pp. 327-331
-
-
Brunengraber, H.1
Roe, C.R.2
-
38
-
-
67349144436
-
Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
-
doi: 10.1007/s00125-009-1319-6
-
MacDonald MJ, Longacre MJ, Langberg EC, Tibell A, Kendrick MA, et al. (2009) Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes. Diabetologia 52: 1087-1091. doi:10.1007/s00125-009-1319-6. PubMed: 19296078.
-
(2009)
Diabetologia
, vol.52
, pp. 1087-1091
-
-
MacDonald, M.J.1
Longacre, M.J.2
Langberg, E.C.3
Tibell, A.4
Kendrick, M.A.5
-
39
-
-
79956322775
-
Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets
-
doi: 10.1074/jbc.M111.241182
-
MacDonald MJ, Longacre MJ, Stoker SW, Kendrick M, Thonpho A, et al. (2011) Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets. J Biol Chem 286: 18383-18396. doi:10.1074/jbc.M111.241182. PubMed: 21454710.
-
(2011)
J Biol Chem
, vol.286
, pp. 18383-18396
-
-
MacDonald, M.J.1
Longacre, M.J.2
Stoker, S.W.3
Kendrick, M.4
Thonpho, A.5
-
40
-
-
0034072556
-
Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion
-
doi: 10.2337/diabetes.49.5.718
-
Farfari S, Schulz V, Corkey B, Prentki M, (2000) Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion. Diabetes 49: 718-726. doi:10.2337/diabetes.49.5.718. PubMed: 10905479.
-
(2000)
Diabetes
, vol.49
, pp. 718-726
-
-
Farfari, S.1
Schulz, V.2
Corkey, B.3
Prentki, M.4
-
41
-
-
0036300460
-
Critical role for cataplerosis via citrate in glucose-regulated insulin release
-
doi: 10.2337/diabetes.51.7.2018
-
Flamez D, Berger V, Kruhøffer M, Orntoft T, Pipeleers D, et al. (2002) Critical role for cataplerosis via citrate in glucose-regulated insulin release. Diabetes 51: 2018-2024. doi:10.2337/diabetes.51.7.2018. PubMed: 12086928.
-
(2002)
Diabetes
, vol.51
, pp. 2018-2024
-
-
Flamez, D.1
Berger, V.2
Kruhøffer, M.3
Orntoft, T.4
Pipeleers, D.5
-
42
-
-
0036894293
-
Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach
-
doi: 10.2337/diabetes.51.2007.S389
-
Newgard CB, Lu D, Jensen MV, Schissler J, Boucher A, et al. (2002) Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach. Diabetes 51 (Suppl 3):: S389-S393. doi:10.2337/diabetes.51.2007.S389. PubMed: 12475781.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Newgard, C.B.1
Lu, D.2
Jensen, M.V.3
Schissler, J.4
Boucher, A.5
-
43
-
-
33646579537
-
Anaplerotic roles of pyruvate carboxylase in mammalian tissues
-
doi: 10.1007/s00018-005-5410-y
-
Jitrapakdee S, Vidal-Puig A, Wallace JC, (2006) Anaplerotic roles of pyruvate carboxylase in mammalian tissues. Cell Mol Life Sci 63: 843-854. doi:10.1007/s00018-005-5410-y. PubMed: 16505973.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 843-854
-
-
Jitrapakdee, S.1
Vidal-Puig, A.2
Wallace, J.C.3
-
44
-
-
33846954392
-
Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion
-
PubMed: 17102138
-
Pongratz RL, Kibbey RG, Shulman GI, Cline GW, (2007) Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion. J Biol Chem 282: 200-207. PubMed: 17102138.
-
(2007)
J Biol Chem
, vol.282
, pp. 200-207
-
-
Pongratz, R.L.1
Kibbey, R.G.2
Shulman, G.I.3
Cline, G.W.4
-
45
-
-
47749151440
-
Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt
-
doi: 10.1074/jbc.M709235200
-
Li C, Nissim I, Chen P, Buettger C, Najafi H, et al. (2008) Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt. J Biol Chem 283: 17238-17249. doi:10.1074/jbc.M709235200. PubMed: 18445600.
-
(2008)
J Biol Chem
, vol.283
, pp. 17238-17249
-
-
Li, C.1
Nissim, I.2
Chen, P.3
Buettger, C.4
Najafi, H.5
-
46
-
-
0037022527
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)
-
doi: 10.1073/pnas.052005699
-
Lu D, Mulder H, Zhao P, Burgess SC, Jensen MV, et al. (2002) 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc Natl Acad Sci U S A 99: 2708-2713. doi:10.1073/pnas.052005699. PubMed: 11880625.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2708-2713
-
-
Lu, D.1
Mulder, H.2
Zhao, P.3
Burgess, S.C.4
Jensen, M.V.5
-
47
-
-
57649118511
-
Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase
-
doi: 10.1074/jbc.M804170200
-
Hasan NM, Longacre MJ, Stoker SW, Boonsaen T, Jitrapakdee S, et al. (2008) Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase. J Biol Chem 283: 28048-28059. doi:10.1074/jbc.M804170200. PubMed: 18697738.
-
(2008)
J Biol Chem
, vol.283
, pp. 28048-28059
-
-
Hasan, N.M.1
Longacre, M.J.2
Stoker, S.W.3
Boonsaen, T.4
Jitrapakdee, S.5
-
48
-
-
0037131246
-
beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats
-
doi: 10.1074/jbc.M207157200
-
Liu YQ, Jetton TL, Leahy JL, (2002) beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats. J Biol Chem 277: 39163-39168. doi:10.1074/jbc.M207157200. PubMed: 12147706.
-
(2002)
J Biol Chem
, vol.277
, pp. 39163-39168
-
-
Liu, Y.Q.1
Jetton, T.L.2
Leahy, J.L.3
-
49
-
-
0029976878
-
Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats
-
doi: 10.2337/diab.45.11.1626
-
MacDonald MJ, Tang J, Polonsky KS, (1996) Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats. Diabetes 45: 1626-1630. doi:10.2337/diab.45.11.1626. PubMed: 8866570.
-
(1996)
Diabetes
, vol.45
, pp. 1626-1630
-
-
MacDonald, M.J.1
Tang, J.2
Polonsky, K.S.3
-
50
-
-
0026611169
-
[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis
-
doi: 10.1073/pnas.89.13.5744
-
Tal M, Wu YJ, Leiser M, Surana M, Lodish H, et al. (1992) [Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis. Proc Natl Acad Sci U S A 89: 5744-5748. doi:10.1073/pnas.89.13.5744. PubMed: 1631055.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 5744-5748
-
-
Tal, M.1
Wu, Y.J.2
Leiser, M.3
Surana, M.4
Lodish, H.5
-
51
-
-
80053553928
-
Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells
-
doi: 10.1248/bpb.34.1613
-
Kojima K, Shimada T, Nagareda Y, Watanabe M, Ishizaki J, et al. (2011) Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells. Biol Pharm Bull 34: 1613-1618. doi:10.1248/bpb.34.1613. PubMed: 21963504.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 1613-1618
-
-
Kojima, K.1
Shimada, T.2
Nagareda, Y.3
Watanabe, M.4
Ishizaki, J.5
-
52
-
-
65349141758
-
Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin
-
doi: 10.1038/aps.2008.17
-
Wu SY, Wang GF, Liu ZQ, Rao JJ, Lü L, et al. (2009) Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin. Acta Pharmacol Sin 30: 202-208. doi:10.1038/aps.2008.17. PubMed: 19122671.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 202-208
-
-
Wu, S.Y.1
Wang, G.F.2
Liu, Z.Q.3
Rao, J.J.4
Lü, L.5
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