A half century (1961-2011) of applying microsurgery to experimental liver research

World Journal of Hepatology

Volumn 4, Issue 7, 2012, Pages 199-208

  Aller, Maria Angeles ^a   Arias, Natalia ^b   Prieto, Isabel ^c   Agudo, Salvador ^d   Gilsanz, Carlos ^d   Lorente, Laureano ^a   Arias, Jorge Luis ^b   Arias, Jaime ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

^c AUTONOMOUS UNIVERSITY OF MADRID   (Spain)

^d Arganda del Rey   (Spain)

Author keywords

Cholestasis; Hepatectomies; Liver transplantation; Microsurgery; Portacaval shunts; Portal hypertension

Indexed keywords

EID: 84885958589     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v4.i7.199     Document Type: Review

References (70)

1. Lee S. Manual of Microsurgery. Boca Raton, FL: CRC Press Inc., 1985
2. Aller MA, Arias J. Microsurgery: Instruments and techniques. In: Microsurgery in Liver Research. Aller MA, Arias J, Eds. Bentham e-book, 2009: 32-48
3. Hoyt RF, Clevenger RR, McGehee JA. Microsurgical instrumentation and suture material. Lab Anim (NY) 2001; 30: 38-45
4. Kühnel TS, Müller GH. Experimental animal studies of clip-induced microvascular trauma. Microsurgery 2004; 24: 241-247
5. Hoyt RF, Clevenger RR, McGehee JA. Introduction to microsurgery: an emerging discipline in biomedical research. Lab Anim (NY) 2001; 30: 26-35
6. LEE SH, FISHER B. Portacaval shunt in the rat. Surgery 1961; 50: 668-672
7. Lee S. Connections between experimental microsurgery and general surgery. Microsurgery 1998; 18: 445
8. Aller MA, Mendez M, Nava MP, Lopez L, Arias JL, Arias J. The value of microsurgery in liver research. Liver Int 2009; 29: 1132-1140
9. Orloff MJ. Portal hypertension and porto-caval shunt. In:Surgical Research. Souba WW, Wilmore DW Eds. Waltham, MA: Academic Press, 2001 637-701
10. Abraldes JG, Pasarín M, García-Pagán JC. Animal models of portal hypertension. World J Gastroenterol 2006; 12: 6577-6584
11. Martell M, Coll M, Ezkurdia N, Raurell I, Genescà J. Physiopathology of splanchnic vasodilation in portal hypertension. World J Hepatol 2010; 2: 208-220
12. Chojkier M, Groszmann RJ. Measurement of portal-systemic shunting in the rat by using gamma-labeled microspheres. Am J Physiol 1981; 240: G371-G375
13. Aller MA, Mendez M, Nava MP, Lopez L, Curras D, De Paz A, Arias JL, Arias J. Portal surgery: Portosystemic shunts and portal hypertension. In: Microsurgery in Liver Research. Aller MA, Arias J, Eds. Bentham e-book, 2009: 117-133
14. Aller MA, Arias JL, Cruz A, Arias J. Inflammation: a way to understanding the evolution of portal hypertension. Theor Biol Med Model 2007; 4: 44
15. Blanco-Rivero J, Aller MA, Arias J, Ferrer M, Balfagón G. Long-term portal hypertension increases the vasodilator response to acetylcholine in rat aorta: role of prostaglandin I2. Clin Sci (Lond) 2009; 117: 365-374
16. Aller MA, Vara E, García C, Nava MP, Angulo A, Sánchez-Patán F, Calderón A, Vergara P, Arias J. Hepatic lipid metabolism changes in short- and long-term prehepatic portal hypertensive rats. World J Gastroenterol 2006; 12: 6828-6834
17. Aller MA, Arias JL, Arias J. The mast cell integrates the splanchnic and systemic inflammatory response in portal hypertension. J Transl Med 2007; 5: 44
18. Sánchez-Patán F, Anchuelo R, Aller MA, Vara E, García C, Nava MP, Arias J. Chronic prehepatic portal hypertension in the rat: is it a type of metabolic inflammatory syndrome? Lipids Health Dis 2008; 7: 4
19. O'Connor MJ. Mechanical biliary obstruction. A review of the multisystemic consequences of obstructive jaundice and their impact on perioperative morbidity and mortality. Am Surg 1985; 51: 245-251
20. Kountouras J, Billing BH, Scheuer PJ. Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br J Exp Pathol 1984; 65: 305-311
21. Holmberg JT, Hederström E, Ihse I. A method to prevent recanalization of the transected bile duct in the rat. Scand J Gastroenterol 1985; 20: 428-432
22. Aller MA, Duran M, Ortega L, Arias JL, Nava MP, Prieto I, Arias J. Comparative study of macro- and microsurgical extrahepatic cholestasis in the rat. Microsurgery 2004; 24: 442-447
23. Aller MA, Lorente L, Alonso S, Arias J. A model of cholestasis in the rat, using a microsurgical technique. Scand J Gastroenterol 1993; 28: 10-14
24. Sánchez-Patán F, Anchuelo R, Corcuera MT, Casado I, Gómez-Aguado F, Aller MA, Cruz A, Alonso MJ, Arias J. Biliary fibrosis in microsurgical extrahepatic cholestasis in the rat. Microsurgery 2008; 28: 361-366
25. Aller MA, Arias JL, García-Domínguez J, Arias JI, Durán M, Arias J. Experimental obstructive cholestasis: the wound-like inflammatory liver response. Fibrogenesis Tissue Repair 2008; 1: 6
26. Aller MA, Arias JL, Prieto I, Losada M, Arias J. Bile duct ligation: step-by-step to cholangiocyte inflammatory tumorigenesis. Eur J Gastroenterol Hepatol 2010; 22: 651-661
27. Aller MA, Nava MP, Arias JL, Durán M, Prieto I, Llamas MA, Arias J. Microsurgical extrahepatic cholestasis in the rat: a long-term study. J Invest Surg 2004; 17: 99-104
28. Aller MA, Prieto I, Argudo S, de Vicente F, Santamaría L, de Miguel MP, Arias JL, Arias J. The interstitial lymphatic peritoneal mesothelium axis in portal hypertensive ascites: when in danger, go back to the sea. Int J Inflam 2010; 2010: 148689
29. Aller MA, Lorente L, Prieto I, Arias J. Hepatectomies. In: Microsurgery in Liver Diseases. Aller MA, Arias J, Eds. Bentham e books, 2009: 157-67
30. Higgins GM, Anderson RM. Experimental pathology of the liver: restoration of the white liver rat following partial surgical removal. Arch Pathol 1931; 12: 186-202
31. Lorente L, Rodriguez G, Alonso MS, Duran HJ, Aller MA, Arias J. Hepatic caudate process anatomy in Wistar rats. Int J Surg Sci 1995; 2: 196-198
32. Lorente L, Aller MA, Rodriguez J, Duran MC, Duran HJ, Alonso MS, Arias J. Surgical anatomy of the liver in Wistar rats. Surg Res Comm 1995; 17: 113-121
33. Kogure K, Ishizaki M, Nemoto M, Kuwano H, Makuuchi M. A comparative study of the anatomy of rat and human livers. J Hepatobiliary Pancreat Surg 1999; 6: 171-175
34. Castaing D, Houssin D, Bismuth H. Anatomy of the liver and portal system of the rat. In: Hepatic and Portal Surgery in the Rat. Castaing D, Houssin D, Bismuth, Eds. Paris: Editorial Masson, 1980: 27-46
35. Madrahimov N, Dirsch O, Broelsch C, Dahmen U. Marginal hepatectomy in the rat: from anatomy to surgery. Ann Surg 2006; 244: 89-98
36. Martins PN, Theruvath TP, Neuhaus P. Rodent models of partial hepatectomies. Liver Int 2008; 28: 3-11
37. Aller MA, Lorente L, Prieto I, Moquillaza LM, Arias J. Hepatectomies in the rat: A look at the caudate process through microsurgery. Dig Liver Dis 2009; 41: 695-699
38. Mitchell C, Willenbring H. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nat Protoc 2008; 3: 1167-1170
39. Rodríguez G, Lorente L, Durán HJ, Aller MA, Arias J. A 70% hepatectomy in the rat using a microsurgical technique. Int Surg 1999; 84: 135-138
40. Fernández M, Semela D, Bruix J, Colle I, Pinzani M, Bosch J. Angiogenesis in liver disease. J Hepatol 2009; 50: 604-620
41. Chen GW, Zhang MZ, Zhao LF, Xu CS. Expression patterns and action analysis of genes associated with physiological responses during rat liver regeneration: Innate immune response. World J Gastroenterol 2006; 12: 7852-7858
42. Stenton GR, Vliagoftis H, Befus AD. Role of intestinal mast cells in modulating gastrointestinal pathophysiology. Ann Allergy Asthma Immunol 1998; 81: 1-11; quiz 12-5
43. Moquillaza LM, Aller MA, Nava MP, Santamaría L, Vergara P, Arias J. Partial hepatectomy, partial portal vein stenosis and mesenteric lymphadenectomy increase splanchnic mast cell infiltration in the rat. Acta Histochem 2010; 112: 372-382
44. Lee S, Edgington TS. Heterotopic liver transplantation utilizing inbred rat strains. I. Characterization of allogeneic graft rejection and the effects of biliary obstruction and portal vein circulation on liver regeneration. Am J Pathol 1968; 52: 649-669
45. Lorente L, Arias J, Aller MA, Ispizua JI, Rodriguez J, Durán H. Heterotopic auxiliary liver transplantation with portal flow. Gradual development of the collateral circulation. HPB Surg 1990; 2: 281-291; discussion 291-293
46. Rozga J, Demetriou AA. Animal models of liver failure. In: Surgical Research. Souba WW, Wilmore DW, Eds. San Diego, CA: Academic Press, 2001: 623-636
47. He Y, Zhou J, Dou KF, Chen Y. A rat model for acute hepatic failure. Hepatobiliary Pancreat Dis Int 2003; 2: 423-425
48. Ogata T, Yamashita K, Horiuchi H, Okuda K, Todo S. A novel tumor necrosis factor-alpha suppressant, ONO-SM362, prevents liver failure and promotes liver regeneration after extensive hepatectomy. Surgery 2008; 143: 545-555
49. Azoulay D, Astarcioglu I, Astarcioglu H, Lemoine A, Majno P, Bismuth H. A new technique of one-stage total hepatectomy in the rat. Surgery 1997; 121: 219-222
50. Yamaguchi Y, Bollinger RR, DeFaria E, Landis B, Quarfordt S. A simplified single stage total hepatectomy in the rat with maintenance of gastrointestinal absorptive function. Hepatology 1989; 9: 69-74
51. Sherlock S. The portal venous system and portal hypertension. In: Diseases of the Liver and Biliary System. 8th ed.Sherlock S, Ed. London: Blackwell Scientific Publishers, 1989: 151-207
52. Sánchez-Patán F, Anchuelo R, Aller MA, Arias J. A modification to facilitate end-to-side portacaval anastomosis in rats: description of a modified technique. Int J Surg 2007; 5: 433-435
53. Sánchez-Patán F, Blanco R, Aller MA, Anchuelo R, Román FS, Arias J. End-to-side portacaval shunt: a simplified technique. J Invest Surg 2007; 20: 135-138
54. Dasarathy S, Mullen KD, Conjeevaram HS, Kaminsky-Russ K, Wills LA, McCullough AJ. Preservation of portal pressure improves growth and metabolic profile in the male portacaval-shunted rat. Dig Dis Sci 2002; 47: 1936-1942
55. Méndez M, Méndez-López M, López L, Aller MA, Arias J, Cimadevilla JM, Arias JL. Spatial memory alterations in three models of hepatic encephalopathy. Behav Brain Res 2008; 188: 32-40
56. Arias JL, Aller MA, Sánchez-Patan F, Arias J. The inflammatory bases of hepatic encephalopathy. Eur J Gastroenterol Hepatol 2006; 18: 1297-1310
57. López L, Burgos P, Santín LJ, Begega A, Arias J, Lorente L, Arias JL. Portacaval shunt control animals: physiological consequences derived from the sham operation. Lab Anim 1997; 31: 225-230
58. Lee S, Charters AC, Chandler JG, Orloff MJ. A technique for orthotopic liver transplantation in the rat. Transplantation 1973; 16: 664-669
59. Kamada N, Calne RY. Orthotopic liver transplantation in the rat. Technique using cuff for portal vein anastomosis and biliary drainage. Transplantation 1979; 28: 47-50
60. Kamada N, Calne RY. A surgical experience with five hundred thirty liver transplants in the rat. Surgery 1983; 93: 64-69
61. De Pedro JA, Brandau D, Delgado MA, Aller MA, Jimenez G, Arias J, Duran H A surgical experience with fifty liver transplantations in the rat. Ann NY Acad Sci 1986; 463: 278-280
62. Settaf A, Gugenheim J, Houssin D, Bismuth H. [Liver transplantation in the rat. Technical considerations apropos of 247 cases]. J Chir (Paris) 1987; 124: 39-42
63. Ariyakhagorn V, Schmitz V, Olschewski P, Polenz D, Boas-Knoop S, Neumann U, Puhl G. Improvement of microsurgical techniques in orthotopic rat liver transplantation. J Surg Res 2009; 153: 332-339
64. Inoue S, Tahara K, Shimizu H, Yoshino H, Suzuki C, Kaneko T, Hakamata Y, Takahashi M, Murakami T, Kaneko M, Kobayashi E. Rat liver transplantation for total vascular reconstruction, using a suture method. Microsurgery 2003; 23: 470-475
65. Oldani G, Maestri M, Gaspari A, Lillo E, Angelastri G, Lenti LM, Rademacher J, Alessiani M, Dionigi P. A novel technique for rat liver transplantation using Quick Linker system: a preliminary result. J Surg Res 2008; 149: 303-309
66. Zhu H, Marco C, Gianfranco F. Early changes of graft function, cytokines and superoxide dismutase serum levels after donor liver denervation and Kupffer cell depletion in a rat-to-rat liver transplantation model. Hepatobiliary Pancreat Dis Int 2009; 8: 152-156
67. Hölzen JP, Palmes D, Langer M, Spiegel HU. Microsurgical training curriculum for learning kidney and liver transplantation in the rat. Microsurgery 2005; 25: 614-623
68. Lee S, Edgington TS, Orloff MJ. The role of afferent blood supply in regeneration of liver isografts in rats. Surg Forum 1968; 19: 360-362
69. Fisher B, Szuch P, Fisher ER. Evaluation of a humoral factor in liver regeneration utilizing liver transplants. Cancer Res 1971; 31: 322-331
70. Hess F, Jerusalem C, van der Heyde MN. Advantages of auxiliary liver homotransplantation in rats. Arch Surg 1972; 104: 76-80