Efficacies of calcium-EDTA in combination with imipenem in a murine model of sepsis caused by Escherichia coli with NDM-1 β-lactamase

Journal of Infection and Chemotherapy

Volumn 19, Issue 5, 2013, Pages 992-995

  Yoshizumi, Ayumi ^a   Ishii, Yoshikazu ^a   Livermore, David M ^b,c   Woodford, Neil ^b   Kimura, Soichiro ^a   Saga, Tomoo ^a   Harada, Sohei ^a   Yamaguchi, Keizo ^a   Tateda, Kazuhiro ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Antibiotic resistance; Calcium EDTA; Metallo lactamase inhibitor; NDM 1

Indexed keywords

BETA LACTAMASE; CARBAPENEM DERIVATIVE; CILASTATIN PLUS IMIPENEM; EDETATE CALCIUM; NEW DELHI METALLO BETA LACTAMASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL LOAD; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; ESCHERICHIA COLI; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; MOUSE; NONHUMAN; SEPSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL LOAD; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; EDETIC ACID; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; IMIPENEM; MICE; MICROBIAL SENSITIVITY TESTS; SEPSIS;

EID: 84885956709     PISSN: 1341321X     EISSN: 14377780     Source Type: Journal    
DOI: 10.1007/s10156-012-0528-y     Document Type: Article

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