Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype

Journal of Hepatology

Volumn 59, Issue 5, 2013, Pages 957-963

  Han, Hwalih ^b   Noureddin, Mazen ^b   Witthaus, Michael ^b   Park, Yoon J ^b   Hoofnagle, Jay H ^b   Liang, T Jake ^b   Rotman, Yaron ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NONE

Author keywords

Fever; Hepatitis C; IL28B; Interferon alfa; Temperature; Treatment

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 28B; PARACETAMOL; PEGINTERFERON ALPHA2A; PROGRAMMED DEATH 1 LIGAND 1; RIBAVIRIN; VIRUS RNA;

ABDOMINAL PAIN; ADULT; ARTICLE; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; ELECTRONIC THERMOMETER; FEMALE; FEVER; GAMMA INTERFERON INDUCIBLE GENE 10; GENE; GENE EXPRESSION; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; INTERFERON REGULATORY FACTOR 7 GENE; INTERLEUKIN 28B GENE; ISG15 GENE; LIVER BIOPSY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MOUTH TEMPERATURE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROGRAMMED DEATH 1 LIGAND 1 GENE; PROTEIN BLOOD LEVEL; RETROSPECTIVE STUDY; RSAD2 GENE; SINGLE DRUG DOSE; SINGLE NUCLEOTIDE POLYMORPHISM; TEMPERATURE MEASUREMENT; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT RESPONSE; TYMPANIC THERMOMETER;

EARLY VIROLOGICAL RESPONSE; EVR; FEVER; HCV; HEPATITIS C; HEPATITIS C VIRUS; IFN; IL28B; INTERFERON; INTERFERON ALFA; INTERFERON-GAMMA-INDUCIBLE PROTEIN-10; INTERFERON-STIMULATED GENE; IP-10; ISG; PEGIFN; PEGINTERFERON ALFA 2A; PGE2; PROSTAGLANDIN E2; RAPID VIROLOGICAL RESPONSE; RVR; SUSTAINED VIROLOGICAL RESPONSE; SVR; TEMPERATURE; TREATMENT;

ADULT; ANTIVIRAL AGENTS; BODY TEMPERATURE; CHEMOKINE CXCL10; FEMALE; FEVER; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; INTERFERON-ALPHA; INTERLEUKINS; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS; RETROSPECTIVE STUDIES; RIBAVIRIN; RNA, VIRAL; TREATMENT OUTCOME;

EID: 84885947858     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.07.004     Document Type: Article

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