New structure of phage-related islands carrying fusB and a virulence gene in fusidic acid-resistant Staphylococcus epidermidis

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 11, 2013, Pages 5737-5739

  Chen, Hsiao Jan ^a   Chang, Ya Chun ^a   Tsai, Jui Chang ^a,b   Hung, Wei Chun ^a   Lin, Yu Tzu ^a   You, Shang Jie ^a   Tseng, Sung Pin ^c   Teng, Lee Jene ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; DNA FLANKING REGION; FUSB GENE; GENE LOCATION; GENE STRUCTURE; LINKAGE ANALYSIS; NONHUMAN; PATHOGENICITY ISLAND; PRIORITY JOURNAL; STAPHYLOCOCCUS EPIDERMIDIS; VAPE GENE;

ADAPTATION, PHYSIOLOGICAL; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; FUSIDIC ACID; GENE EXPRESSION REGULATION, BACTERIAL; GENOMIC ISLANDS; MICROBIAL SENSITIVITY TESTS; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS PHAGES; VIRULENCE; VIRULENCE FACTORS;

EID: 84885941899     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01433-13     Document Type: Article

References (17)

1. McLaws F, Chopra I, O'Neill AJ. 2008. High prevalence of resistance to fusidic acid in clinical isolates of Staphylococcus epidermidis. J. Antimicrob. Chemother. 61:1040-1043.
2. Chen HJ, Tsai JC, Hung WC, Tseng SP, Hsueh PR, Teng LJ. 2011. Identification of fusB-mediated fusidic acid resistance islands in Staphylococcus epidermidis isolates. Antimicrob. Agents Chemother. 55:5842-5849.
3. Liu D, Swiatlo E, Austin FW, Lawrence ML. 2006. Use of a putative transcriptional regulator gene as target for specific identification of Staphylococcus epidermidis. Lett. Appl. Microbiol. 43:325-330.
4. Chen HJ, Hung WC, Tseng SP, Tsai JC, Hsueh PR, Teng LJ. 2010. Fusidic acid resistance determinants in Staphylococcus aureus clinical isolates. Antimicrob. Agents Chemother. 54:4985-4991.
5. Hacker J, Kaper JB. 2000. Pathogenicity islands and the evolution of microbes. Annu. Rev. Microbiol. 54:641-679.
6. Novick RP, Christie GE, Penades Jr. 2010. The phage-related chromosomal islands of Gram-positive bacteria. Nat. Rev. Microbiol. 8:541-551.
7. Baba T, Takeuchi F, Kuroda M, Yuzawa H, Aoki K, Oguchi A, Nagai Y, Iwama N, Asano K, Naimi T, Kuroda H, Cui L, Yamamoto K, Hiramatsu K. 2002. Genome and virulence determinants of high virulence community-acquired MRSA. Lancet 359:1819-1827.
8. Madhusoodanan J, Seo KS, Remortel B, Park JY, Hwang SY, Fox LK, Park YH, Deobald CF, Wang D, Liu S, Daugherty SC, Gill AL, Bohach GA, Gill SR. 2011. An enterotoxin-bearing pathogenicity island in Staphylococcus epidermidis. J. Bacteriol. 193:1854-1862.
9. Bloomfield GA, Whittle G, McDonagh MB, Katz ME, Cheetham BF. 1997. Analysis of sequences flanking the vap regions of Dichelobacter nodosus: evidence for multiple integration events, a killer system, and a new genetic element. Microbiology 143(Part 2):553-562.
10. Lindsay JA, Ruzin A, Ross HF, Kurepina N, Novick RP. 1998. The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus. Mol. Microbiol. 29:527-543.
11. Yarwood JM, McCormick JK, Paustian ML, Orwin PM, Kapur V, Schlievert PM. 2002. Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3. Implications for the evolution of staphylococcal pathogenicity islands. J. Biol. Chem. 277:13138-13147.
12. Subedi A, Ubeda C, Adhikari RP, Penades JR, Novick RP. 2007. Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock. Microbiology 153:3235-3245.
13. Frebourg NB, Lefebvre S, Baert S, Lemeland JF. 2000. PCR-based assay for discrimination between invasive and contaminating Staphylococcus epidermidis strains. J. Clin. Microbiol. 38:877-880.
14. Rohde H, Kalitzky M, Kroger N, Scherpe S, Horstkotte MA, Knobloch JK, Zander AR, Mack D. 2004. Detection of virulence-associated genes not useful for discriminating between invasive and commensal Staphylococcus epidermidis strains from a bone marrow transplant unit. J. Clin. Microbiol. 42:5614-5619.
15. Huang YH, Tseng SP, Hu JM, Tsai JC, Hsueh PR, Teng LJ. 2007. Clonal spread of SCCmec type IV methicillin-resistant Staphylococcus aureus between community and hospital. Clin. Microbiol. Infect. 13:717-724.
16. Conlan S, Mijares LA, Becker J, Blakesley RW, Bouffard GG, Brooks S, Coleman H, Gupta J, Gurson N, Park M, Schmidt B, Thomas PJ, Otto M, Kong HH, Murray PR, Segre JA. 2012. Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates. Genome Biol. 13:R64. doi:10.1186/gb-2012-13-7-r64.
17. Archer GL. 1991. Alteration of cutaneous staphylococcal flora as a consequence of antimicrobial prophylaxis. Rev. Infect. Dis. 13(Suppl. 10): S805-S809.