Experimental characterization and modeling of twin-screw extruder elements for pharmaceutical hot melt extrusion

AIChE Journal

Volumn 59, Issue 11, 2013, Pages 4440-4450

  Eitzlmayr, Andreas ^a   Khinast, Johannes ^a   Hörl, Gudrun ^b   Koscher, Gerold ^b   Reynolds, Gavin ^c   Huang, Zhenyu ^c   Booth, Jonathan ^c   Shering, Philip ^c  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH   (Austria)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Hot melt extrusion; Pressure characteristic; Rheology; Screw element; Soluplus

Indexed keywords

EXTRUDERS; MELT SPINNING; RHEOLOGY;

AXIAL PRESSURE GRADIENTS; CO-ROTATING TWIN SCREW EXTRUDERS; EXPERIMENTAL CHARACTERIZATION; HOT MELT EXTRUSION; ONE-DIMENSIONAL SIMULATIONS; PRESSURE CHARACTERISTICS; SCREW ELEMENTS; SOLUPLUS;

EXTRUSION;

EID: 84885869795     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.14184     Document Type: Article

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