Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents

Human Molecular Genetics

Volumn 22, Issue 21, 2013, Pages 4405-4416

  Capdevila Nortes, Xavier ^a   López Hernández, Tania ^a,e   Apaja, Pirjo M ^c   de Heredia, Miguel López ^d,e   Sirisi, Sònia ^a,d   Callejo, Gerard ^b,f   Arnedo, Tanit ^a,e   Nunes, Virginia ^b,d,e   Lukacs, Gergely L ^c   Gasull, Xavier ^b,f   Estévez, Raúl ^a,b,e  

^a Depto de Biol Cel Y Fisiol F   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c MCGILL UNIVERSITY   (Canada)

^d BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; MESSENGER RNA; MLC1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CARBOXY TERMINAL SEQUENCE; CELL JUNCTION; CELL MATURATION; CELL MEMBRANE; CELL SURFACE; CELL VACUOLE; CELL VOLUME; CELLULAR DISTRIBUTION; FEMALE; GAIN OF FUNCTION MUTATION; GAP JUNCTION; HELA CELL; HUMAN; HUMAN CELL; LEUKODYSTROPHY; LOSS OF FUNCTION MUTATION; MEGALENCEPHALIC LEUKOENCEPHALOPATHY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; WILD TYPE;

ANIMALS; ASTROCYTES; CHLORIDE CHANNELS; CYSTS; GENETIC VARIATION; HELA CELLS; HEREDITARY CENTRAL NERVOUS SYSTEM DEMYELINATING DISEASES; HUMANS; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; MUTATION; PHENOTYPE; PROTEIN STABILITY; PROTEINS; RATS; RNA INTERFERENCE; VACUOLES;

EID: 84885817574     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt290     Document Type: Article

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