A large-scale behavioral screen to identify neurons controlling motor programs in the drosophila brain

G3: Genes, Genomes, Genetics

Volumn 3, Issue 9, 2013, Pages 1629-1637

  Flood, Thomas F ^a   Gorczyca, Michael ^a   White, Benjamin H ^b   Ito, Kei ^c   Yoshihara, Motojiro ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Command; Drosophila; Gal4; Neurons; Trpa1; TRPM8

Indexed keywords

TRANSCRIPTION FACTOR GAL4; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; ION CHANNEL;

ADULT; ARTICLE; BEHAVIOR; BEHAVIOR CHANGE; BRAIN; BRAIN CELL; CONTROLLED STUDY; DROSOPHILA; FEMALE; GENE EXPRESSION; LOW TEMPERATURE; MALE; NERVE CELL; NONHUMAN; PROGENY; TRANSGENE; BRAIN ELECTROPHYSIOLOGY; BRAIN NERVE CELL; COLD SENSITIVITY; FEEDING; FOLLOW UP; GENETIC SCREENING; MOTONEURON; MOTOR ACTIVITY; NERVE STIMULATION; PARALYSIS;

COMMAND NEURONS; DROSOPHILA; GAL4; TRPA1; TRPM8;

ANIMALS; BRAIN; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; LOCOMOTION; NERVE NET; NEURONS; REGULATORY SEQUENCES, NUCLEIC ACID; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE; TRANSCRIPTION FACTORS; TRPC CATION CHANNELS; TRPM CATION CHANNELS;

EID: 84885816185     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.006205     Document Type: Article

References (44)

1. Allen, M. J., T. A. Godenschwege, M. A. Tanouye, and P. Phelan, 2006 Making an escape: development and function of the Drosophila giant fibre system. Semin. Cell Dev. Biol. 17: 31-41.
2. Bentley, D., and R. R. Hoy, 1974 The neurobiology of cricket song. Sci. Am. 231: 34-50.
3. Brand, A. H., and N. Perrimon, 1993 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
4. Card, G., and M. Dickinson, 2008 Performance trade-offs in the flight initiation of Drosophila. J. Exp. Biol. 211: 341-353.
5. Clyne, J. D., and G. Miesenbock, 2008 Sex-specific control and tuning of the pattern generator for courtship song in Drosophila. Cell 133: 354-363.
6. Davis, W. J., 1979 Behavioural hierarchies. Trends Neurosci. 2: 5-7.
7. Dethier, V. G., 1976 Hungry Fly, Harvard University Press, Cambridge, MA.
8. Edwards, D. H., W. J. Heitler, and F. B. Krasne, 1999 Fifty years of a command neuron: the neurobiology of escape behavior in the crayfish. Trends Neurosci. 22: 153-161.
9. Feinberg, E. H., M. K. Vanhoven, A. Bendesky, G. Wang, R. D. Fetter et al. 2008 GFP Reconstitution Across Synaptic Partners (GRASP) defines cell contacts and synapses in living nervous systems. Neuron 57: 353-363.
10. Flood, T. F., S. Iguchi, M. Gorczyca, B. White, K. Ito et al. 2013 A single pair of interneurons commands the Drosophila feeding motor program. Nature 499: 83-87.
11. Frost, W. N., and P. S. Katz, 1996 Single neuron control over a complex motor program. Proc. Natl. Acad. Sci. USA 93: 422-426.
12. Gordon, M. D., and K. Scott, 2009 Motor control in a Drosophila taste circuit. Neuron 61: 373-384.
13. Hamada, F. N., M. Rosenzweig, K. Kang, S. R. Pulver, A. Ghezzi et al. 2008 An internal thermal sensor controlling temperature preference in Drosophila. Nature 454: 217-220.
14. Ikeda, K., and C. A. Wiersma, 1964 Autogenic Rhythmicity in the Abdominal Ganglia of the Crayfish: The Control of Swimmeret Movements. Comp. Biochem. Physiol. 12: 107-115.
15. Jenett,A., G. M. Rubin, T. T. Ngo, D. Shepherd,C.Murphy et al. 2012 AGAL4-driver line resource for Drosophila neurobiology. Cell Rep 2: 991-1001.
16. Kamikouchi, A., T. Shimada, and K. Ito, 2006 Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster. J. Comp. Neurol. 499: 317-356.
17. Kohatsu, S., M. Koganezawa, and D. Yamamoto, 2011 Female contact activates male-specific interneurons that trigger stereotypic courtship behavior in Drosophila. Neuron 69: 498-508.
18. Kravitz, E. A., and R. Huber, 2003 Aggression in invertebrates. Curr. Opin. Neurobiol. 13: 736-743.
19. Kristan, W. B., 2008 Neuronal decision-making circuits. Curr. Biol. 18: R928-R932.
20. Kupfermann, I., and K. R. Weiss, 2001 Motor program selection in simple model systems. Curr. Opin. Neurobiol. 11: 673-677.
21. Lai, S. L., and T. Lee, 2006 Genetic mosaic with dual binary transcriptional systems in Drosophila. Nat. Neurosci. 9: 703-709.
22. Lima, S. Q., and G. Miesenbock, 2005 Remote control of behavior through genetically targeted photostimulation of neurons. Cell 121: 141-152.
23. Luan, H., F. Diao, N. C. Peabody, and B. H. White, 2012 Command and compensation in a neuromodulatory decision network. J. Neurosci. 32: 880-889.
24. Marder, E., and R. L. Calabrese, 1996 Principles of rhythmic motor pattern generation. Physiol. Rev. 76: 687-717.
25. McKemy, D. D., W. M. Neuhausser, and D. Julius, 2002 Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416: 52-58.
26. Miyazaki, T., and K. Ito, 2010 Neural architecture of the primary gustatory center of Drosophila melanogaster visualized with GAL4 and LexA enhancer-trap systems. J. Comp. Neurol. 518: 4147-4181.
27. Nakai, J., M. Ohkura, and K. Imoto, 2001 A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein. Nat. Biotechnol. 19: 137-141.
28. Nilsen, S. P., Y. B. Chan, R. Huber, and E. A. Kravitz, 2004 Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 101: 12342-12347.
29. O'Kane, C. J., andW. J. Gehring, 1987 Detection in situ of genomic regulatory elements in Drosophila. Proc. Natl. Acad. Sci. USA 84: 9123-9127.
30. Peabody, N. C., J. B. Pohl, F. Diao, A. P. Vreede, D. J. Sandstrom et al. 2009 Characterization of the decision network for wing expansion in Drosophila using targeted expression of the TRPM8 channel. J. Neurosci. 29: 3343-3353.
31. Phillis, R. W., A. T. Bramlage, C. Wotus, A. Whittaker, L. S. Gramates et al. 1993 Isolation of mutations affecting neural circuitry required for grooming behavior in Drosophila melanogaster. Genetics 133: 581-592.
32. Pulver, S. R., S. L. Pashkovski, N. J. Hornstein, P. A. Garrity, and L. C. Griffith, 2009 Temporal dynamics of neuronal activation by Channelrhodopsin-2 and TRPA1 determine behavioral output in Drosophila larvae. J. Neurophysiol. 101: 3075-3088.
33. Shafer, O. T., D. J. Kim, R. Dunbar-Yaffe, V. O. Nikolaev, M. J. Lohse et al. 2008 Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. Neuron 58: 223-237.
34. Shen, K., and C. W. Cowan, 2010 Guidance molecules in synapse formation and plasticity. Cold Spring Harb. Perspect. Biol. 2: a001842.
35. Struhl, G., and K. Basler, 1993 Organizing activity of wingless protein in Drosophila. Cell 72: 527-540.
36. Tinbergen, N., 1951 The Study of Instinct, Clarendon Press, Oxford.
37. Tinette, S., L. Zhang, A. Garnier, G. Engler, S. Tares et al. 2007 Exploratory behaviour in NO-dependent cyclase mutants of Drosophila shows defects in coincident neuronal signalling. BMC Neurosci. 8: 65.
38. von Philipsborn, A. C., T. Liu, J. Y. Yu, C. Masser, S. S. Bidaye et al. 2011 Neuronal control of Drosophila courtship song. Neuron 69: 509- 522.
39. Wiersma, C. A., and K. Ikeda, 1964 Interneurons Commanding Swimmeret Movements in the Crayfish, Procambarus Clarki (Girard). Comp. Biochem. Physiol. 12: 509-525.
40. Yang, C. H., P. Belawat, E. Hafen, L. Y. Jan, and Y. N. Jan, 2008 Drosophila egg-laying site selection as a system to study simple decision-making processes. Science 319: 1679-1683.
41. Yoshihara, M., 2012 Simultaneous recording of calcium signals from identified neurons and feeding behavior of Drosophila melanogaster. J. Vis. Exp. 62: e3625
42. Yoshihara, M., and K. Ito, 2000 Improved Gal4 screening kit for large-scale generation of enhancer-trap strains. Drosoph. Inf. Serv. 83: 199-202.
43. Yoshihara, M., B. Adolfsen, K. T. Galle, and J. T. Littleton, 2005 Retrograde signaling by Syt 4 induces presynaptic release and synapse-specific growth. Science 310: 858-863.
44. Zar, J., 1999 Biostatistical Analysis, Ed. 4. Prentice Hall, Upper Saddle River, NJ.