Drosophila KDEL Receptor Function in the Embryonic Salivary Gland and Epidermis

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Abrams, Elliott W ^a,b   Cheng, Yim Ling ^a   Andrew, Deborah J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CELL PROTEIN; INSECT PROTEIN; KDEL RECEPTOR; PROTEIN BOCA; PROTEIN WBL; RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTHROPOD LARVA; ARTICLE; CAENORHABDITIS ELEGANS; CELLULAR DISTRIBUTION; CREBA GENE; CUTICLE; DROSOPHILA; EMBRYO; EMBRYO CELL; EMBRYO DEVELOPMENT; ENDOPLASMIC RETICULUM; EPIDERMIS; EPIDERMIS CELL; EUKARYOTE; FAT BODY; GENE; GENE EXPRESSION; GENE FUNCTION; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HOMOZYGOTE; KDELR RECEPTOR GENE; LETHALITY; LOSS OF FUNCTION MUTATION; MAMMAL; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SALIVARY GLAND; SECRETORY CELL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; UPREGULATION;

ANIMALS; CAENORHABDITIS ELEGANS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A; DROSOPHILA; DROSOPHILA PROTEINS; EPIDERMIS; GENES, INSECT; MUTATION; RECEPTORS, PEPTIDE; SACCHAROMYCES CEREVISIAE; SALIVARY GLANDS; SECRETORY PATHWAY; TRANSCRIPTION FACTORS;

EID: 84885786826     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077618     Document Type: Article

References (42)

1. Sitia R, Braakman I, (2003) Quality control in the endoplasmic reticulum protein factory. Nature 426: 891-894. doi:10.1038/nature02262. PubMed: 14685249.
2. Pelham HR, Hardwick KG, Lewis MJ, (1988) Sorting of soluble ER proteins in yeast. EMBO J 7: 1757-1762. PubMed: 3049074.
3. Townsley FM, Wilson DW, Pelham HR, (1993) Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. EMBO J 12: 2821-2829. PubMed: 8392934.
4. Scheel AA, Pelham HR, (1998) Identification of amino acids in the binding pocket of the human KDEL receptor. J Biol Chem 273: 2467-2472. doi:10.1074/jbc.273.4.2467. PubMed: 9442098.
5. Munro S, Pelham HR, (1987) A C-terminal signal prevents secretion of luminal ER proteins. Cell 48: 899-907. doi:10.1016/0092-8674(87)90086-9. PubMed: 3545499.
6. Denecke J, De Rycke R, Botterman J, (1992) Plant and mammalian sorting signals for protein retention in the endoplasmic reticulum contain a conserved epitope. EMBO J 11: 2345-2355. PubMed: 1376250.
7. Lewis MJ, Pelham HR, (1992) Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum. Cell 68: 353-364. doi:10.1016/0092-8674(92)90476-S. PubMed: 1310258.
8. Lewis MJ, Sweet DJ, Pelham HR, (1990) The ERD2 gene determines the specificity of the luminal ER protein retention system. Cell 61: 1359-1363. doi:10.1016/0092-8674(90)90699-F. PubMed: 2194671.
9. Wilson DW, Lewis MJ, Pelham HR, (1993) pH-dependent binding of KDEL to its receptor in vitro. J Biol Chem 268: 7465-7468. PubMed: 8385108.
10. Lewis MJ, Pelham HR, (1990) A human homologue of the yeast HDEL receptor. Nature 348: 162-163. doi:10.1038/348162a0. PubMed: 2172835.
11. Napier RM, Fowke LC, Hawes C, Lewis M, Pelham HR, (1992) Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum. J Cell Sci 102: 261-271. PubMed: 1383243.
12. Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, et l (2000) The genome sequence of Drosophila melanogaster. Science 287: 2185-2195. doi:10.1126/science.287.5461.2185. PubMed: 10731132.
13. Abrams EW, Andrew DJ, (2005) CrebA regulates secretory activity in the Drosophila salivary gland and epidermis. Development 132: 2743-2758. doi:10.1242/dev.01863. PubMed: 15901661.
14. Fox RM, Hanlon CD, Andrew DJ, (2010) The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 191: 479-492. doi:10.1083/jcb.201004062. PubMed: 21041443.
15. Kopczynski CC, Noordermeer JN, Serano TL, Chen WY, Pendleton JD, Lewis S, Goodman CS, Rubin GM, (1998) A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Proc Natl Acad Sci U S A 95: 9973-9978. doi:10.1073/pnas.95.17.9973. PubMed: 9707585.
16. Franc NC, Heitzler P, Ezekowitz RA, White K, (1999) Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. Science 284: 1991-1994. doi:10.1126/science.284.5422.1991. PubMed: 10373118.
17. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG, (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25: 4876-4882. doi:10.1093/nar/25.24.4876. PubMed: 9396791.
18. Clegg NJ, Whitehead IP, Brock JK, Sinclair DA, Mottus R, Stromotich G, Harrington MJ, Grigliatti TA, (1993) A cytogenetic analysis of chromosomal region 31 of Drosophila melanogaster. Genetics 134: 221-230. PubMed: 8514131.
19. Lehmann R, Tautz D, (1994) In situ hybridization to RNA. Methods Cell Biol 44: 575-598. doi:10.1016/S0091-679X(08)60933-4. PubMed: 7535885.
20. Reuter R, Panganiban GE, Hoffmann FM, Scott MP, (1990) Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 110: 1031-1040. PubMed: 1983113.
21. Abrams EW, Mihoulides WK, Andrew DJ, (2006) Fork head and Sage maintain a uniform and patent salivary gland lumen through regulation of two downstream target genes PH4alphaSG1 and PH4alphaSG2. Development 133: 3517-3527.
22. Culi J, Mann RS, (2003) Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell 112: 343-354. doi:10.1016/S0092-8674(02)01279-5. PubMed: 12581524.
23. Konsolaki M, Schüpbach T, (1998) windbeutel, a gene required for dorsoventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum. Genes Dev 12: 120-131. doi:10.1101/gad.12.1.120. PubMed: 9420336.
24. Raykhel I, Alanen H, Salo K, Jurvansuu J, Nguyen VD, Latva-Ranta M, Ruddock L, (2007) A molecular specificity code for the three mammalian KDEL receptors. J Cell Biol 179: 1193-1204. doi:10.1083/jcb.200705180. PubMed: 18086916.
25. Semenza JC, Hardwick KG, Dean N, Pelham HR, (1990) ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell 61: 1349-1357. doi:10.1016/0092-8674(90)90698-E. PubMed: 2194670.
26. Valcárcel R, Weber U, Jackson DB, Benes V, Ansorge W, Bohmann D, Mlodzik M, (1999) Sec61beta, a subunit of the protein translocation channel, is required during Drosophila development. J Cell Sci 112: 4389-4396. PubMed: 10564656.
27. Abrams EW, Andrew DJ, (2002) Prolyl 4-hydroxylase alpha-related proteins in Drosophila melanogaster: tissue-specific embryonic expression of the 99F8-9 cluster. Mech Dev 112: 165-171. doi:10.1016/S0925-4773(01)00636-0. PubMed: 11850189.
28. Kivirikko KI, Pihlajaniemi T, (1998) Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl. Retrieved onpublished at whilst December year 1111 from pp. 4-hydroxylases. Adv; Relat Enzymol Areas. Mol Biol 72: 325-398.
29. Vuori K, Pihlajaniemi T, Myllylä R, Kivirikko KI, (1992) Site directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera fugiperda insect cells. EMBO J 11: 4213-4217. PubMed: 1327760.
30. Culi J, Springer TA, Mann RS, (2004) Boca-dependent maturation of b-propeller/EGF modules in low-density lipoprotein receptor proteins. EMBO J 23: 1372-1380. doi:10.1038/sj.emboj.7600132. PubMed: 15014448.
31. Sen J, Goltz JS, Konsolaki M, Schüpbach T, Stein D, (2000) Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe. Development 127: 5541-5550. PubMed: 11076773.
32. Jackson MR, Nilsson T, Peterson PA, (1990) Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO J 9: 3153-3162. PubMed: 2120038.
33. Cosson P, Letourneur F, (1994) Coatomer interaction with di-lysine endoplasmic reticulum retention motifs. Science 263: 1629-1631. doi:10.1126/science.8128252. PubMed: 8128252.
34. Dominguez M, Dejgaard K, Füllekrug J, Dahan S, Fazel A, Paccaud JP, Thomas DY, Bergeron JJ, Nilsson T, (1998) gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer. J Cell Biol 140: 751-765. doi:10.1083/jcb.140.4.751. PubMed: 9472029.
35. Sönnichsen B, Füllekrug J, Nguyen Van P, Diekmann W, Robinson DG, Mieskes G, (1994) Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum. J Cell Sci 107: 2705-2717. PubMed: 7876339.
36. Nishikawa S, Nakano A, (1993) Identification of a gene required for membrane protein retention in the early secretory pathway. Proc Natl Acad Sci U S A 90: 8179-8183. doi:10.1073/pnas.90.17.8179. PubMed: 8367481.
37. Beh CT, Rose MD, (1995) Two redundant systems maintain levels of resident proteins within the yeast endoplasmic reticulum. Proc Natl Acad Sci U S A 92: 9820-9823. doi:10.1073/pnas.92.21.9820. PubMed: 7568225.
38. Sidrauski C, Cox JS, Walter P, (1996) tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell 87: 405-413. doi:10.1016/S0092-8674(00)81361-6. PubMed: 8898194.
39. Wang P, Li B, Zhou L, Fei E, Wang G, (2011) The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins. Neuroscience 190: 43-55. doi:10.1016/j.neuroscience.2011.06.008. PubMed: 21684323.
40. Giannotta M, Ruggiero C, Grossi M, Cancino J, Capitani M, Pulvirenti T, Consoli GM, Geraci C, Fanelli F, Luini A, Sallese M, (2012) The KDEL receptor couples to Gzq/qq to activate Src kinases and regulate transport through the Golgi. EMBO J 31: 2869-2881. doi:10.1038/emboj.2012.134. PubMed: 22580821.
41. Cabrera M, Muñiz M, Hidalgo J, Vega L, Martín ME, Velasco A, (2003) The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus. Mol Biol Cell 14: 4114-4125. doi:10.1091/mbc.E03-04-0194. PubMed: 14517323.
42. Marygold SJ, Leyland PC, Seal RL, Goodman JL, Thurmond JR, Strelets VM, Wilson RJ, FlyBase, Consortium (2013) Flybase: improvements to the bibliography. Nucleic Acids Res 41: D751-D757. doi:10.1093/nar/gks1024. PubMed: 23125371.