Continua or classes? Vexed questions on the latent structure of schizophrenia

Advances in Schizophrenia Research 2009

Volumn , Issue , 2010, Pages 333-355

  Linscott, Richard J ^a   Lenzenweger, Mark F ^b,c   Van Os, Jim ^d,e  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b BINGHAMTON UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84885782790     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-0913-8_18     Document Type: Chapter

References (82)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. Author, Washington, DC, 2000.
2. Beauchaine, T. P. & Beauchaine, R. J., III A comparison of maximum covariance and k-means cluster analysis in classifying cases into known taxon groups. Psychological Methods 7: 245-261, 2002.
3. Beauchaine, T. P., Lenzenweger, M. F. & Waller, N. G. Schizotypy, taxometrics, and disconfirming theories in soft science. Personality and Individual Differences 44: 1652-1662, 2008.
4. Bell, M. Cognitively disorganized schizophrenia: a taxometric analysis of PANSS ratings. Schizophrenia Research 24: 98, 1997.
5. Blanchard, J. J., Gangestad, S. W., Brown, S. A. & Horan, W. P. Hedonic capacity and schizotypy revisited: A taxometric analysis of social anhedonia. Journal of Abnormal Psychology 109: 87-95, 2000. (Pubitemid 30155409)
6. Blanchard, J. J., Horan, W. P. & Collins, L. M. Examining the latent structure of negative symptoms: Is there a distinct subtype of negative symptom schizophrenia? Schizophrenia Research 77: 151-165, 2005. (Pubitemid 41112209)
7. Brenner, V. & Raulin, M. L. Validation of the Schizotypal Taxon Using Graphical Taxometric Techniques. 102nd Annual American Psychological Convention, Los Angeles, CA, 1994.
8. Brenner, V., Raulin, M. L. & Young, B. L. Comparing the Sensitivity of Two Taxometric Techniques in Detecting the Schizotypal Taxonomy. Annual Convention of the Society for Research on Psychopathology, Iowa City, IA, 1995.
9. Brockington, I. F., Kendell, R. E., Wainwright, S., Hillier, V. F. & Walker, J. The distinction between the affective psychoses and schizophrenia. British Journal of Psychiatry 135: 243-248, 1979. (Pubitemid 9244808)
10. Chapman, L. J., Chapman, J. P., Kwapil, T. R., Eckblad, M. & Zinser, M. C. Putatively psychosisprone subjects 10 years later. Journal of Abnormal Psychology 103: 171-183, 1994. (Pubitemid 24152791)
11. Chapman, L. J., Chapman, J. P. & Miller, E. N. Reliabilities and intercorrelations of eight measures of proneness to psychosis. Journal of Consulting and Clinical Psychology 85: 374-382, 1982.
12. Chapman, L. J., Chapman, J. P. & Raulin, M. L. Scales for physical and social anhedonia. Journal of Abnormal Psychology 85: 374-382, 1976.
13. Chapman, L. J., Chapman, J. P. & Raulin, M. L. Body-image aberration in schizophrenia. Journal of Abnormal Psychology 87: 399-407, 1978. (Pubitemid 9010146)
14. Claridge, G. Schizotypy: Implications for Illness and Health. Oxford University Press, New York, 1997.
15. Claridge, G. & Broks, P. Schizotypy and hemispheric function-I. Theoretical considerations and the measurement of schizotypy. Personality and Individual Differences 5: 633-648, 1984.
16. Claridge, G., et al. The factor structure of 'schizotypal' traits: A large replication study. British Journal of Clinical Psychology 35: 103-115, 1996. (Pubitemid 26070231)
17. Cleland, C. M., Rothschild, L. & Haslam, N. Detecting latent taxa: Monte Carlo comparison of taxometric, mixture model, and clustering procedures. Psychological Reports 87: 37-47, 2000.
18. Cuesta, M. J., Ugarte, M. D., Goicoa, T., Eraso, S. & Peralta, V. A taxometric analysis of schizophrenia symptoms. Psychiatry Research 150: 245-253, 2007. (Pubitemid 46470049)
19. Daniel, D. G., Goldberg, T. E., Gibbons, R. D. & Weinberger, D. R. Lack of a bimodal distribution of ventricular size in schizophrenia: A Gaussian mixture analysis of 1056 cases and controls. Biological Psychiatry 30: 887-903, 1991.
20. Eckblad, M. L. & Chapman, L. J. Magical ideation as an indicator of schizotypy. Journal of Consulting and Clinical Psychology 51: 215-225, 1983.
21. Erlenmeyer-Kimling, L., Golden, R. R. & Cornblatt, B. A. A taxometric analysis of cognitive and neuromotor variables in children at risk for schizophrenia. Journal of Abnormal Psychology 98: 203-208, 1989. (Pubitemid 19213232)
22. Fossati, A., Raine, A., Borroni, S. & Maffei, C. Taxonic structure of schizotypal personality in nonclinical subjects: Issues of replicability and age consistency. Psychiatry Research 152: 103-112, 2007. (Pubitemid 47212484)
23. Gibbons, R. D., Dorus, E., Ostrow, D. G., Pandey, G. N., Davis, J. M. & Levy, D. L. Mixture distributions in psychiatric research. Biological Psychiatry 19: 935-961, 1984. (Pubitemid 14031219)
24. Golden, R. R. A taxometric model for the detection of a conjectured latent taxon. Multivariate Behavioral Research 17: 389-416, 1982.
25. Golden, R. R. & Meehl, P. E. Detection of the schizoid taxon with MMPI indicators. Journal of Abnormal Psychology 88: 217-233, 1979. (Pubitemid 9221956)
26. Golden, R. R. & Meehl, P. E. Detection of biological sex: An empirical test of cluster methods. Multivariate Behavioral Research 15: 475-496, 1980.
27. Gottesman, I. I. Schizophrenia Genesis: The Origins of Madness. Freeman, New York, 1991.
28. Grayson, D. A. Can categorical and dimensional views of psychiatric illness be distinguished? British Journal of Psychiatry 151: 355-361, 1987. (Pubitemid 17139008)
29. Harvey, I., Mcguffin, P., Williams, M. & Toone, B. K. The ventricle-brain ratio (VBR) in functional psychoses: An admixture analysis. Psychiatry Research: Neuroimaging 35: 61-69, 1990. (Pubitemid 20203216)
30. Horan, W. P., Blanchard, J. J., Gangestad, S. W. & Kwapil, T. R. The psychometric detection of schizotypy: Do putative schizotypy indicators identify the same latent class? Journal of Abnormal Psychology 113: 339-357, 2004. (Pubitemid 39038109)
31. Jones, P., Rodgers, B., Murray, R. & Marmot, M. Child development risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 344: 1398-1402, 1994a. (Pubitemid 24365314)
32. Jones, P. B., et al. Cerebral ventricle dimensions as risk factors for schizophrenia and affective psychosis: An epidemiological approach to analysis. Psychological Medicine 24: 995-1011, 1994b.
33. Keller, F., Jahn, T. & Klein, C. Anwendung von taxometrischen methoden und von mischverteilungsmodellen zur erfassung der schizotypie. In: Andresen, B. & Mas, R. (eds.) Schizotypie: Psychometrische entwicklungen und biopsychologische forschungsansätze, Hogrefe, Göttingen, Germany, pp. 391-412, 2001.
34. Kendell, R. E. & Brockington, I. F. The identification of disease entities and the relationship between schizophrenic and affective psychoses. British Journal of Psychiatry 137: 324-331, 1980. (Pubitemid 11243351)
35. Kendell, R. E. & Gourlay, J. The clinical distinction between the affective psychoses and schizophrenia. British Journal of Psychiatry 117: 261-266, 1970.
36. Korfine, L. & Lenzenweger, M. F. The taxonicity of schizotypy: A replication. Journal of Abnormal Psychology 104: 26-31, 1995.
37. Lenzenweger, M. F. Deeper into the schizotypy taxon: On the robust nature of maximum covariance analysis. Journal of Abnormal Psychology 108: 182-187, 1999. (Pubitemid 29108322)
38. Lenzenweger, M. F. & Korfine, L. Confirming the latent structure and base rate of schizotypy: A taxometric analysis. Journal of Abnormal Psychology 101: 567-571, 1992.
39. Lenzenweger, M. F., Mclachlan, G. & Rubin, D. B. Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling. Journal of Abnormal Psychology 116: 16-29, 2007. (Pubitemid 46328606)
40. Linscott, R. J. The latent structure and coincidence of hypohedonia and schizotypy and their validity as indices of psychometric risk for schizophrenia. Journal of Personality Disorders 21: 225-242, 2007. (Pubitemid 46911573)
41. Linscott, R. J., Allardyce, J. & Van Os, J. Seeking verisimilitude in a class: A systematic review of evidence that the criterial clinical symptoms of schizophrenia are taxonic. Schizophrenia Bulletin in press: 1-19, 2009.
42. Linscott, R. J. & Knight, R. G. Potentiated automatic memory in schizotypy. Personality and Individual Differences 37: 1503-1517, 2004. (Pubitemid 39332577)
43. Linscott, R. J., Marie, D., Arnott, K. L. & Clark, B. L. Over-representation of Maori New Zealanders among adolescents in a schizotypy taxon. Schizophrenia Research 84: 289-296, 2006.
44. Lo, Y., Matthysse, S., Rubin, D. B. & Holzman, P. S. Permutation tests for detecting and estimating mixtures in task performance within groups. Statistics in Medicine 21: 1937-1953, 2002. (Pubitemid 34732649)
45. Lowrie, G. S. & Raulin, M. L. Search for Schizotypic and Nonschizotypic Taxonomies in a College Population. Sixty-First Annual Convention of the Eastern Psychological Association, Philadelphia, PA, 1990.
46. Lowrie, G. S. & Raulin, M. L. Testing the construct validity of Meehl's taxonic model of schizotypy: Taxometric search techniques applied to self-report measures of schizotypic signs. Unpublished manuscript, 1996.
47. Macfarlane, R. M. Taxometric analysis of schizotypy. Unpublished thesis, University of Iowa, 1996.
48. Maxwell, A. E. Multivariate statistical methods and classification problems. British Journal of Psychiatry 119: 121-127, 1971.
49. Meehl, P. E. Maxcov-Hitmax: A taxonomic search method for loose genetic syndromes. In: Meehl, P. E. (eds.) Psychodiagnosis: Selected papers, University of Minnesota Press, Minneapolis, pp. 200-224, 1973.
50. Meehl, P. E. A funny thing happened to us on the way to the latent entities. Journal of Personality Assessment 43: 564-581, 1979.
51. Meehl, P. E. Factors and taxa, traits and types, differences of degree and differences in kind. Journal of Personality 60: 117-174, 1992.
52. Meehl, P. E. Bootstraps taxometrics: Solving the classification problem in psychopathology. American Psychologist 50: 266-275, 1995.
53. Meehl, P. E. Clarifications about taxometric method. Applied and Preventive Psychology 8: 165-174, 1999.
54. Meehl, P. E. What's in a taxon? Journal of Abnormal Psychology 113: 39-43, 2004. (Pubitemid 38228775)
55. Meehl, P. E. & Yonce, L. J. Taxometric analysis: I. Detecting taxonicity with two quantitative indicators using means above and below a sliding cut (MAMBAC procedure). Psychological Reports 74: 1059-1274, 1994.
56. Meyer, T. D. & Keller, F. Exploring the latent structure of the perceptual aberration, magical ideation, and physical anhedonia scales in a German sample. Journal of Personality Disorders 15: 521-535, 2001. (Pubitemid 34008333)
57. Mishlove, M. & Chapman, L. J. Social anhedonia in the prediction of psychosis proneness. Journal of Abnormal Psychology 94: 384-396, 1985. (Pubitemid 16147325)
58. Murphy, E. A. One cause? Many causes? The argument from the bimodal distribution. Journal of Chronic Diseases 17: 301-324, 1964.
59. Muthén, B. & Asparouhov, T. Item response mixture modeling: Application to tobacco dependence criteria. Addictive Behaviors 31: 1050-1066, 2006. (Pubitemid 43775959)
60. Pauler, D. K., Escobar, M. D., Sweeney, J. A. & Greenhouse, J. Mixture models for eye-tracking data: A case study. Statistics in Medicine 15: 1365-1376, 1996. (Pubitemid 26242546)
61. Peralta, V. & Cuesta, M. J. How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment. Schizophrenia Research 49: 269-285, 2001. (Pubitemid 32453228)
62. Peralta, V. & Cuesta, M. J. The nosology of psychotic disorders: A comparison among competing classification systems. Schizophrenia Bulletin 29: 413-425, 2003. (Pubitemid 37339378)
63. Poulton, R., Caspi, A., Moffitt, T. E., Cannon, M., Murray, R. & Harrington, H. Children's self-reported psychotic symptoms and adult schizophreniform disorder: A 15-year longitudinal study. Archives of General Psychiatry 57: 1053-1058, 2000.
64. Raine, A. The SPQ: A scale for the assessment of schizotypal personality based on DSM-III-R criteria. Schizophrenia Bulletin 17: 555-564, 1991.
65. Rawlings, D., Williams, B., Haslam, N. & Claridge, G. Taxometric analysis supports a dimensional latent structure for schizotypy. Personality and Individual Differences 44: 1640-1651, 2008.
66. Ross, D. E., Ochs, A. L., Pandurangi, A. K., Thacker, L. R. & Kendler, K. S. Mixture analysis of smooth pursuit eye movements in schizophrenia. Psychophysiology 33: 390-397, 1996. (Pubitemid 26230725)
67. Ross, D. E., et al. Eye tracking disorder in schizophrenia is characterized by specific ocular motor defects and is associated with the deficit syndrome. Biological Psychiatry 42: 781-796, 1997. (Pubitemid 27468206)
68. Ross, R. G., et al. Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypes. Psychophysiology 39: 809-819, 2002. (Pubitemid 36025322)
69. Rubin, D. B. & Wu, Y. N. Modeling schizophrenic behavior using general mixture components. Biometrics 53: 243-261, 1997. (Pubitemid 27131898)
70. Ruscio, J. & Ruscio, A. M. Clarifying boundary issues in psychopathology: The role of taxometrics in a comprehensive program of structural research. Journal of Abnormal Psychology 113: 24-38, 2004. (Pubitemid 38228774)
71. Schooler, N. R., et al. Relapse and rehospitalization during maintenance treatment of schizophrenia. The effects of dose reduction and family treatment. Archives of General Psychiatry 54: 453-463, 1997. (Pubitemid 27198207)
72. Shevlin, M., Adamson, G., Vollebergh, W., De Graaf, R. & Van Os, J. An application of item response mixture modelling to psychosis indicators in two large community samples. Social Psychiatry and Psychiatric Epidemiology 42: 771-779, 2007a. (Pubitemid 47470750)
73. Shevlin, M., Murphy, J., Dorahy, M. J. & Adamson, G. The distribution of positive psychosislike symptoms in the population: A latent class analysis of the National Comorbidity Survey. Schizophrenia Research 89: 101-109, 2007b. (Pubitemid 44881308)
74. Sweeney, J. A., Clementz, B. A., Escobar, M. D., Li, S., Pauler, D. K. & HAAS, G. L. Mixture analysis of pursuit eye-tracking dysfunction in schizophrenia. Biological Psychiatry 34: 331-340, 1993. (Pubitemid 23285419)
75. Tyrka, A. R., et al. The latent structure of schizotypy: I. Premorbid indicators of a taxon of individuals at risk for schizophrenia-spectrum disorders. Journal of Abnormal Psychology 104: 173-183, 1995.
76. Van Kampen, D. Genetic and environmental influences on pre-schizophrenic personality: MAXCOV-HITMAX and LISREL analyses. European Journal of Personality 13: 63-80, 1999.
77. Van Os, J., Linscott, R. J., Myin-Germeys, I., Delespaul, P. & Krabbendam, L. A systematic review and meta-analysis of the psychosis continuum: Evidence for a psychosis proneness-persistenceimpairment model of psychotic disorder. Psychological Medicine 39(2): 179-195, 2009.
78. Van Os, J., Linscott, R. J., Myin-Germeys, I., Delespaul, P. & Krabbendam, L. A systematic review and meta-analysis of the psychosis continuum: Evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychological Medicine 39: 179-195, 2009.
79. Venables, P. H., Wilkins, S., Mitchell, D. A., Raine, A. & Bailes, K. A scale for the measurement of schizotypy. Personality and Individual Differences 11: 481-495, 1990.
80. Waller, N. G. & Meehl, P. E. Multivariate Taxometric Procedures: Distinguishing Types from Continua. Sage, Thousand Oaks, CA, 1998.
81. Whitehead, K. V. Precursors for Schizophrenia: Are Schizotaxia and Schizotypy Related? Unpublished thesis, University of Otago, 2005.
82. World Health Organization. ICD-10: International Statistical Classification of Diseases and Related Health Problems (10th ed.). World Health Organization, Geneva, 2004.