Efficient scale-up strategy for spray-dried amorphous dispersions

Drug Development and Delivery

Volumn 13, Issue 8, 2013, Pages 54-62

  Dubose, Devon ^a   Settell, Dana ^b   Baumann, John ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; SOLVENT;

AMORPHOUS DISPERSION; ARTICLE; COMPRESSION; COMPUTER SIMULATION; DENSITY; DISPERSION; EVAPORATION; FLOW RATE; MELTING POINT; NEBULIZATION; PARTICLE SIZE; QUALITY CONTROL; SCALE UP; SPRAY DRYING; THERMODYNAMICS;

EID: 84885772016     PISSN: 15372898     EISSN: 1944818X     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (8)

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2. Baumann JM, Dobry D, Ray RJ. Formulation development - amorphous dispersion formulation development: phase- appropriate integrated approaches to optimizing performance, manufacturability, stability & dosage form. Drug Development & Delivery. 2013;13(6):30-36.
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4. Lefebvre AH. Atomization and sprays. New York: Hemisphere Publishing Corporation; 1989.
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8. International Conference for Harmonisation, Guidance for Industry, Q8(R2) Pharmaceutical Development, November 2009.