Pulse corticosteroid therapy for alopecia areata in children: A retrospective study

Dermatology

Volumn 227, Issue 1, 2013, Pages 37-44

  Friedland, Rivka ^a   Tal, Rotem ^b   Lapidoth, Moshe ^a,c   Zvulunov, Alex ^b   Amitai, Dan Ben ^b,c  

^a RABIN MEDICAL CENTER   (Israel)

^b SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Alopecia areata; Childhood; Corticosteroids; Pulse therapy

Indexed keywords

METHYLPREDNISOLONE;

ABDOMINAL PAIN; ALOPECIA AREATA; ALOPECIA TOTALIS; ALOPECIA UNIVERSALIS; ARTICLE; CHILD; CLINICAL ARTICLE; CORTICOSTEROID THERAPY; DISEASE DURATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG MEGADOSE; DRUG PULSE THERAPY; EPIGASTRIC PAIN; FEMALE; HAIR DISEASE; HUMAN; MALE; MULTIPLE CYCLE TREATMENT; OPHIASIS; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; TREATMENT RESPONSE;

ADOLESCENT; AGE FACTORS; ALOPECIA; ALOPECIA AREATA; CHILD; CHILD, PRESCHOOL; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; METHYLPREDNISOLONE; RECURRENCE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 84885637505     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000351559     Document Type: Article

References (34)

1. Safavi KH, Muller SA, Suman VJ, et al. Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989. Mayo Clin Proc 1995; 70: 628-633
2. Price VH. Alopecia areata: clinical aspects. J Invest Dermatol 1991; 96: 68S.
3. Perret C, Weisner-Menzel L, Happle R. Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata. Acta Derm Venereol 1984: 64: 26-30
4. Seiter S, Ugurel S, Tilgen W, et al. High-dose corticosteroid therapy in the treatment of severe alopecia areata. Dermatology 2001; 202: 230-234
5. Gilhar A, Ullmann Y, Berkutzki T, et al. Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice. J Clin Invest 1998; 101: 62-67
6. Gilhar A, Shalaginov R, Assy B, Serafimovich S, Kalish RS. Alopecia areata is a T-lymphocyte mediated autoimmune disease: lesional human T-lymphocytes transfer alopecia areata to human skin grafts on SCID mice. J Investig Dermatol Symp Proc 1999; 4: 207-210
7. Madani S, Shapiro J. Alopecia areata update. J Am Acad Dermatol 2000; 42: 549-566
8. Perriard-Wolfensberger J, Pasche-Koo F, Mainetti C, et al. Pulse of methylprednisolone in alopecia areata. Dermatology 1993; 187: 282-285
9. Sharma VK. Pulsed administration of corticosteroids in the treatment of alopecia areata. Int J Dermatol 1996; 35: 133-136
10. Friedli A, Labarthe MP, Engelhardt E, et al. Pulse methylprednisolone therapy for severe alopecia areata: an open prospective study of 45 patients. J Am Acad Dermatol 1998; 39: 597-602
11. Alkhalifah A, Alsantali A, Wang E, et al. Alopecia areata update. J Am Acad Dermatol 2010; 62: 191-202
12. Messenger AG, McKillop J, Farrant P, et al. British Association of Dermatologists' guidelines for the management of alopecia areata 2012. Br J Dermatol 2012; 166: 916-926
13. Burton JL, Shuster S. Large doses of glucocorticoid in the treatment of alopecia areata. Acta Derm Venereol 1975; 55: 493-496
14. Kiesch N, Stene JJ, Goens, et al. Pulse steroid therapy for children's severe alopecia areata?. Dermatology 1997; 194: 395-397
15. Tsai YM, Chen W, Hsu ML, et al. High-dose steroid pulse therapy for the treatment of severe alopecia areata. J Formos Med Assoc 2002; 101: 223-226
16. Kurosawa M, Nakagawa S, Mizuashi M, et al. A comparison of efficacy, relapse rate and side effects among three modalities of systemic corticosteroid therapy for alopecia areata. Dermatology 2006; 212: 361-365
17. Nakajima T, Inui S, Itami S. Pulse corticosteroids therapy for alopecia areata: study of 139 patients. Dermatology 2007; 215: 320-324
18. Hubiche T, Leaute-Labreze C, Taieb A, et al. Poor long-term outcome of severe alopecia areata in children treated with high dose pulse corticosteroid therapy. Br J Dermatol 2008; 158: 1136-1137
19. Im M, Lee SS, Lee Y, et al. Prognostic factors in methylprednisolone pulse therapy for alopecia areata. J Dermatol 2011; 38: 767-772
20. Sharma VK, Muralidhar S. Treatment of widespread alopecia areata in young patients with monthly oral corticosteroid pulse. Pediatr Dermatol 1998; 15: 313-317
21. Kar BR, Handa S, Dogra S, et al. Placebo-controlled oral pulse prednisolone therapy in alopecia areata. J Am Acad Dermatol 2005; 52: 287-290
22. Agarwal A, Nath J, Barua KN. Twice weekly 5 mg betamethasone oral pulse therapy in the treatment of alopecia areata. J Eur Acad Dermatol Venereol 2006; 20: 1375-1376
23. Abell E, Gruber HM. A histopathologic reappraisal of alopecia areata. J Cutan Pathol 1987; 14: 347
24. Tosti A, Bellavista S, Iorizzo M. Alopecia areata: a long-term follow-up study of 191 patients. J Am Acad Dermatol 2006; 55: 438-441
25. Winter RJ, Kern F, Blizzard RM. Prednisone therapy for alopecia areata. A follow-up report. Arch Dermatol 1976; 112: 1549-1552
26. Frauman AG. An overview of the adverse reactions to adrenal corticosteroids. Adverse Drug React Toxicol Rev 1996; 15: 203-206
27. Allen DB, Mullen M, Mullen B. A meta-analysis of the effect of oral and inhaled corticosteroids on growth. J Allergy Clin Immunol 1994; 93: 967-976
28. Guilbert TW, Mauger DT, Allen DB, et al. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol 2011; 128: 956-963
29. Sinha A, Bagga A. Pulse steroid therapy. Indian J Pediatr 2008; 75: 1057-1066
30. Klein-Gitelman MS, Pachman LM. Intravenous corticosteroids: adverse reactions are more variable than expected in children. J Rheumatol 1998; 25: 1995-2002
31. Baethge BA, Lidsky MD, Goldberg JW. A study of adverse effects of high-dose intravenous (pulse) methylprednisolone therapy in patients with rheumatic disease. Ann Pharmacother 1992; 26: 316-320
32. Shaheedi-Dadras M, Karami A, Mollaei M, et al. The effect of methylprednisolone pulse therapy plus oral cyclosporine in the treatment of alopecia totalis and universalis. Arch Iranian Med 2008; 11: 90-93
33. Chartaux E, Joly P. Long-term follow-up of the efficacy of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis. Ann Dermatol Venereol 2010; 137: 507-513
34. Droitcourt C, Milpied B, Ezzedine K, et al. Interest of high-dose pulse corticosteroid therapy combined with methotrexate for severe alopecia areata: a retrospective case series. Dermatology 2012; 224: 369-373