The impact of triple anti-platelet therapy for endothelialization and inflammatory response at overlapping bioabsorbable polymer coated drug-eluting stents in a porcine coronary model

International Journal of Cardiology

Volumn 168, Issue 3, 2013, Pages 1853-1858

  Park, Keun Ho ^a   Jeong, Myung Ho ^a   Kim, Jong Min ^a   Park, Dae Sung ^a   Kim, Jung Ha ^a   Lim, Kyung Seob ^a   Lee, Ki Hong ^a   Sim, Doo Sun ^a   Yoon, Hyun Ju ^a   Yoon, Nam Sik ^a   Kim, Kye Hun ^a   Park, Hyung Wook ^a   Hong, Young Joon ^a   Kim, Ju Han ^a   Ahn, Youngkeun ^a   Cho, Jeong Gwan ^a   Park, Jong Chun ^a   Kang, Jung Chaee ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Cilostazol; Drug eluting stents; Inflammation; Restenosis

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; BIOPOLYMER; CILOSTAZOL; CLOPIDOGREL; UMIROLIMUS;

ANGIOCARDIOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DRUG COATING; DRUG ELUTING STENT; FEMALE; FOLLOW UP; HISTOPATHOLOGY; INFLAMMATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MORPHOMETRICS; NEOINTIMA; NONHUMAN; PRIORITY JOURNAL; RIGHT CORONARY ARTERY; SWINE;

CILOSTAZOL; DRUG-ELUTING STENTS; INFLAMMATION; RESTENOSIS;

ABSORBABLE IMPLANTS; ANIMALS; ASPIRIN; COATED MATERIALS, BIOCOMPATIBLE; CORONARY RESTENOSIS; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; DRUG-ELUTING STENTS; FEMALE; INFLAMMATION; NEOINTIMA; PLATELET AGGREGATION INHIBITORS; POLYMERS; SWINE; TETRAZOLES; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84885609799     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.12.070     Document Type: Article

References (31)

1. P.W. Serruys, D.P. Foley, and M.J. Suttorp A randomized comparison of the value of additional stenting after optimal balloon angioplasty for long coronary lesions: final results of the additional value of NIR stents for treatment of long coronary lesions (ADVANCE) study J Am Coll Cardiol 39 2002 393 399
2. R. Kornowski, B. Bhargava, and S. Fuchs Procedural results and late clinical outcomes after percutaneous interventions using long (> or = 25 mm) versus short (< 20 mm) stents J Am Coll Cardiol 35 2000 612 618
3. R. Kornowski, R. Mehran, and L.F. Satler Procedural results and late clinical outcomes following multivessel coronary stenting J Am Coll Cardiol 33 1999 420 426
4. M.C. Morice, P.W. Serruys, and J.E. Sousa A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization N Engl J Med 346 2002 1773 1780
5. S.J. Park, W.H. Shim, and D.S. Ho A paclitaxel-eluting stent for the prevention of coronary restenosis N Engl J Med 348 2003 1537 1545
6. A. Dibra, A. Kastrati, and J. Mehilli Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients N Engl J Med 353 2005 663 670
7. J. Aoki, A.T. Ong, and G.A. Rodriguez Granillo "Full metal jacket" (stented length > or = 64 mm) using drug-eluting stents for de novo coronary artery lesions Am Heart J 150 2005 994 999
8. I. Iakovou, T. Schmidt, and E. Bonizzoni Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents JAMA 293 2005 2126 2130
9. P.K. Kuchulakanti, W.W. Chu, and R. Torguson Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents Circulation 113 2006 1108 1113
10. A.V. Finn, F.D. Kolodgie, and J. Harnek Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents Circulation 112 2005 270 278
11. S.W. Lee, S.W. Park, and Y.H. Kim Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE - Long trial) Am J Cardiol 100 2007 1103 1108
12. R.S. Schwartz, K.C. Huber, and J.G. Murphy Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model J Am Coll Cardiol 19 1992 267 274
13. R. Kornowski, M.K. Hong, F.O. Tio, O. Bramwell, H. Wu, and M.B. Leon In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia J Am Coll Cardiol 31 1998 224 230
14. E. Grube, and L. Buellesfeld BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease Expert Rev Med Devices 3 2006 731 741
15. S. Windecker, P.W. Serruys, and S. Wandel Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial Lancet 372 2008 1163 1173
16. V. Klauss, P.W. Serruys, and T. Pilgrim 2-year clinical follow-up from the randomized comparison of biolimus-eluting stents with biodegradable polymer and sirolimus-eluting stents with durable polymer in routine clinical practice JACC Cardiovasc Interv 4 2011 887 895
17. J. Wykrzykowska, P. Serruys, and P. Buszman The three year follow-up of the randomised "all-comers" trial of a biodegradable polymer biolimus-eluting stent versus permanent polymer sirolimus-eluting stent (LEADERS) Euro Interv 7 2011 789 795
18. G.G. Stefanini, B. Kalesan, and P.W. Serruys Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial Lancet 378 2011 1940 1948
19. J.R. Nebeker, R. Virmani, and C.L. Bennett Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project J Am Coll Cardiol 47 2006 175 181
20. R. Virmani, A. Farb, G. Guagliumi, and F.D. Kolodgie Drug-eluting stents: caution and concerns for long-term outcome Coron Artery Dis 15 2004 313 318
21. B. Azarbal, and J.W. Currier Allergic reactions after the implantation of drug-eluting stents: is it the pill or the polymer? J Am Coll Cardiol 47 2006 182 183
22. S.Y. Lim, M.H. Jeong, and S.J. Hong Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis Circ J 72 2008 463 468
23. L.K. Pendyala, D. Matsumoto, and T. Shinke Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent JACC Cardiovasc Interv 5 2012 436 444
24. Y. Kimura, T. Tani, T. Kanbe, and K. Watanabe Effect of cilostazol on platelet aggregation and experimental thrombosis Arzneimittelforschung 35 1985 1144 1149
25. T. Tanaka, T. Ishikawa, M. Hagiwara, K. Onoda, H. Itoh, and H. Hidaka Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle Pharmacology 36 1988 313 320
26. T. Inoue, T. Uchida, and M. Sakuma Cilostazol inhibits leukocyte integrin Mac-1, leading to a potential reduction in restenosis after coronary stent implantation J Am Coll Cardiol 44 2004 1408 1414
27. T. Inoue, T. Uchida, I. Yaguchi, Y. Sakai, K. Takayanagi, and S. Morooka Stent-induced expression and activation of the leukocyte integrin Mac-1 is associated with neointimal thickening and restenosis Circulation 107 2003 1757 1763
28. S.W. Lee, S.W. Park, and Y.H. Kim Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES trial (a randomized comparison of triple antiplatelet therapy with dual antiplatelet therapy after drug-eluting stent implantation in diabetic patients) J Am Coll Cardiol 51 2008 1181 1187
29. K.H. Park, M.H. Jeong, and M.G. Lee Efficacy of triple anti-platelet therapy including cilostazol in acute myocardial infarction patients undergoing drug-eluting stent implantation Korean Circ J 39 2009 190 197
30. K.H. Park, M.H. Jeong, and M.G. Lee What is the optimal duration of triple anti-platelet therapy in patients with acute myocardial infarction undergoing drug-eluting stent implantation? J Cardiol 57 2011 53 60
31. N. Malik, J. Gunn, and C.M. Holt Intravascular stents: a new technique for tissue processing for histology, immunohistochemistry, and transmission electron microscopy Heart 80 1998 509 516