Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral protease and Tat

Virology Journal

Volumn 10, Issue , 2013, Pages

  Nutan, S K ^a   Modi, Manoj ^a   Dezzutti, Charlene S ^b   Kulshreshtha, Shweta ^c   Rawat, Ajay Kumar Singh ^c   Srivastava, Sharad Kumar ^c   Malhotra, Swadesh ^c   Verma, Anjali ^d   Ranga, Udaykumar ^d   Gupta, Satish Kumar ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

^d JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACACIA CATECHU EXTRACT; ALCOHOL; BUTANOL; CAEFFIC ACID; CATECHIN; CHLOROFORM; FERULIC ACID; INTEGRASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; NATURAL PRODUCT; PETROLEUM ETHER; PLANT EXTRACT; PROTEINASE; RNA DIRECTED DNA POLYMERASE; RUTOSIDE; SAQUINAVIR; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR;

ANTIVIRAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BARK; CELL STRAIN CACO 2; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DOSE RESPONSE; DRUG MECHANISM; DRUG SAFETY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IC 50; IN VITRO STUDY; KERATINOCYTE; LONG TERMINAL REPEAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VIRUS ISOLATION; VIRUS PARTICLE; VIRUS REPLICATION; ACACIA; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; HUMAN IMMUNODEFICIENCY VIRUS 1; IC50; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; PLANT STEM;

ACACIA CATECHU; HUMAN IMMUNODEFICIENCY VIRUS 1; MIMOSA;

ACACIA; ANTIVIRAL AGENTS; CELLS, CULTURED; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84885550636     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-10-309     Document Type: Article

References (44)

1. Antiretroviral therapy and management of HIV infection. Volberding PA, Deeks SG, Lancet 2010 376 49 62 10.1016/S0140-6736(10)60676-9 20609987
2. Molecular basis of human immunodeficiency virus drug resistance: an update. Menendez-Arias L, Antiviral Res 2010 85 210 231 10.1016/j.antiviral. 2009.07.006 19616029
3. Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection. Vlietinck AJ, De Bruyne T, Apers S, Pieters LA, Planta Med 1998 64 97 109 10.1055/s-2006-957384 9525100
4. Anti-HIV activity of medicinal plant extracts. Bedoya LM, Sanchez-Palomino S, Abad MJ, Bermejo P, Alcami J, J Ethnopharmacol 2001 77 113 116 10.1016/S0378-8741(01)00265-3 11483387
5. Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection-an update (1998-2007). Cos P, Maes L, Vlietinck A, Pieters L, Planta Med 2008 74 1323 1337 10.1055/s-2008-1081314 18671200
6. Ethnomedicinal plants and other natural products with anti-HIV active compounds and their putative modes of action. Chinsembu CK, Hedimbi M, Int J Biotech Mol Biol Res 2010 1 74 91
7. Coffin J, Hiughes S, Varmus H, Retroviruses Plainview NY USA: Cold Spring Harbor Laboratory Press 1997
8. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. Mitchell RS, Beitzel BF, Schroder AR, Shinn P, Chen H, Berry CC, Ecker JR, Bushman FD, PLoS Biol 2004 2 234 10.1371/journal.pbio.0020234 15314653
9. Regulatory pathways governing HIV-1 replication. Cullen BR, Greene WC, Cell 1989 58 423 426 10.1016/0092-8674(89)90420-0 2569361
10. Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. el Kharroubi A, Piras G, Zensen R, Martin MA, Mol Cell Biol 1998 18 2535 2544 9566873
11. NF-kappa B and HIV: linking viral and immune activation. Rabson AB, Lin HC, Adv Pharmacol 2000 48 161 207 10987091
12. HIV-1 Tat protein: a target for the development of anti-AIDS therapies. Rusnati M, Presta M, Drugs Future 2002 27 481 493 10.1358/dof.2002.027.05.680587
13. Chemical constituents of Acacia catechu. Li X, Wang H, Liu C, Chen R, Zhongguo Zhong Yao Za Zhi 2010 35 1425 1427 20822013
14. Phenolic compounds from the aqueous extract of Acacia catechu. Li XC, Liu C, Yang LX, Chen RY, J Asian Nat Prod Res 2011 13 826 830 10.1080/10286020. 2011.597384 21830887
15. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Burnett BP, Jia Q, Zhao Y, Levy RM, J Med Food 2007 10 442 451 10.1089/jmf.2006.255 17887937
16. Immunomodulatory activity of Acacia catechu. Ismail S, Asad M, Indian J Physiol Pharmacol 2009 53 25 33 19810573
17. A medicinal plant extract of Scutellaria baicalensis and Acacia Catechu reduced LPS-stimulated gene expression in immune cells: A comprehensive genomic study using QPCR, ELISA, and microarray. Tseng-Crank J, Sung S, Jia Q, Zhao Y, Burnett B, Park DR, Woo SS, J Diet Suppl 2010 7 253 272 10.3109/19390211.2010. 493169 22432516
18. In Vitro antimicrobial activity of Acacia catechu and its phytochemical analysis. Negi BS, Dave BP, Indian J Microbiol 2010 50 369 374 10.1007/s12088-011-0061-1 22282602
19. Antioxidant activity and protective effect against plasmid DNA strand scission of leaf, bark, and heartwood extracts from Acacia catechu. Guleria S, Tiku AK, Singh G, Vyas D, Bhardwaj A, J Food Sci 2011 76 959 964 10.1111/j.1750-3841.2011.02284.x
20. Antifertility activity of a traditional contraceptive pill comprising Acacia catechu, A. Arabica & Tragiain volucerta. Azad-Chowdhury AK, Khaleque RA, Chakder SK, Indian J Med Res 1984 80 372 374 6526444
21. Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-Binding domain of CD4. Yang Q, Stephen AG, Adelsberger JW, Roberts PE, Zhu W, Currens MJ, Feng Y, Crise BJ, Gorelick RJ, Rein AR, Fisher RJ, Shoemaker RH, Sei S, J Virol 2005 79 6122 6133 10.1128/JVI.79.10.6122-6133.2005 15857997
22. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. Balda MS, Whitney JA, Flores C, Gonzalez S, Cereijido M, Matter K, J Cell Biol 1996 134 1031 1049 10.1083/jcb.134.4.1031 8769425
23. In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories. Beer BE, Doncel GF, Krebs FC, Shattock RJ, Fletcher PS, Buckheit RW Jr, Watson K, Dezzutti CS, Cummins JE, Bromley E, Richardson-Harman N, Pallansch LA, Lackman-Smith C, Osterling C, Mankowski M, Miller SR, Catalone BJ, Welsh PA, Howett MK, Wigdahl B, Turpin JA, Reichelderfer P, Antimicrob Agents Chemother 2006 50 713 723 10.1128/AAC.50.2.713-723.2006 16436731
24. Antipyretic, antidiarrhoel, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu wild in albino rats. Ray D, Sharatchandra KH, Thokchom IS, Indian J Pharmacol 2006 38 408 413 10.4103/0253-7613.28207
25. Human epithelial carcinoma cytotoxicity and inhibition of DMBA/TPA induced squamous cell carcinoma in Balb/c mice by Acacia catechu heartwood. Monga J, Chauhan CS, Sharma M, J Pharm Pharmacol 2011 63 1470 1482 10.1111/j.2042-7158.2011.01354.x 21988428
26. Acaconin, a chitinase-like antifungal protein with cytotoxic and anti-HIV-1 reverse transcriptase activities from Acacia confusa seeds. Lam SK, Ng TB, Acta Biochim Pol 2010 57 299 304 20725649
27. Determination of the predominant catechins in Acacia catechu by liquid chromatography/electrospray ionization-mass spectrometry. Shen D, Wu Q, Wang M, Yang Y, Lavoie EJ, Simon JE, J Agric Food Chem 2006 54 3219 3224 10.1021/jf0531499 16637676
28. Differential inhibition of reverse transcriptase and various DNA polymerases by digallic acid and its derivatives. Nakane H, Fukushima M, Ono K, J Nat Prod 1990 53 1234 1240 10.1021/np50071a015 1705574
29. Observations on the inhibition of HIV-1 reverse transcriptase by catechins. Moore PS, Pizza C, Biochem J 1992 288 717 719 1281981
30. Catechins containing a galloyl moiety as potential anti-HIV-1 compounds. Zhao Y, Jiang F, Liu P, Chen W, Yi K, Drugs Discov Today 2012 17 630 635 10.1016/j.drudis.2012.02.015
31. A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function. Mehla R, Bivalkar-Mehla S, Chauhan A, PLoS One 2011 6 27915 10.1371/journal. pone.0027915 22140483
32. The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function. Southgate CD, Green MR, Genes Dev 1991 5 2496 2507 10.1101/gad.5.12b.2496 1752440
33. HIV-1 Tat directly binds to NFkappaB enhancer sequence: role in viral and cellular gene expression. Dandekar DH, Ganesh KN, Mitra D, Nucleic Acids Res 2004 32 1270 1278 10.1093/nar/gkh289 14981150
34. Anti-human immunodeficiency virus type 1 microbicide cellulose acetate 1,2-benzene dicarboxylate in a human in vitro model of vaginal inflammation. Fichorova RN, Zhou F, Ratnam V, Atanassova V, Jiang S, Strick N, Neurath AR, Antimicrob Agents Chemother 2005 49 323 335 10.1128/AAC.49.1.323-335.2005 15616312
35. Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms. Poli G, Bressler P, Kinter A, Duh E, Timmer WC, Rabson A, Justement JS, Stanley S, Fauci AS, J Exp Med 1990 172 151 158 10.1084/jem.172.1.151 2193094
36. IL-8 increases transmission of HIV type 1 in cervical explant tissue. Narimatsu R, Wolday D, Patterson BK, AIDS Res Hum Retroviruses 2005 21 228 233 10.1089/aid.2005.21.228 15795529
37. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, Cost M, Huang Y, Gai F, Billitto N, Lynam JD, Pryke K, Graebing P, Hopkins N, Rooney JF, Friend D, Dezzuti CS, PLoS One 2010 5 9310 10.1371/journal.pone.0009310 20174579
38. Cell-based method and assay for measuring the infectivity and drug sensitivity of immuno-deficiency virus. Kappes JC, Wu X, United States Patent US 2004 6 797,4622 B1
39. HEC-1 cells. Kurarmoto H, Hamano M, Imai M, Hum Cell 2002 2 81 95
40. Generation of papilloma virus-immortalized cell lines from normal human ectocervical, endocervical and vaginal epithelium that maintain expression of tissue specific differentiation proteins. Fichorova RN, Rheinwald JG, Anderson DJ, Biol Reprod 1997 57 847 855 10.1095/biolreprod57.4.847 9314589
41. A bioassay for HIV-1 based on Env-CD4 interaction. Ciminale V, Felber BK, Campbell M, Pavlakis GN, AIDS Res Hum Retroviruses 1990 6 1281 1287 2078409
42. Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR. Liszewski MK, Yu JJ, O'Doherty U, Methods 2009 47 254 260 10.1016/j.ymeth.2009.01.002 19195495
43. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Mosmann T, J Immunol Methods 1983 65 55 63 10.1016/0022-1759(83)90303-4 6606682
44. Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappa B pathway. Marquez N, Sancho R, Bedoya LM, Alcami J, Lopez Perez JL, Feliciano AS, Fiebich BL, Munoz E, Antiviral Res 2005 66 137 145 10.1016/j.antiviral.2005.02.006 15911030