Elevated extracellular HSP70 (HSPA1A) level as an independent prognostic marker of mortality in patients with heart failure

Cell Stress and Chaperones

Volumn 18, Issue 6, 2013, Pages 809-813

  Jenei, Zsigmond M ^a   Gombos, Tímea ^a   Förhécz, Zsolt ^a   Pozsonyi, Zoltán ^a   Karádi, István ^a   Jánoskuti, Lívia ^a   Prohászka, Zoltán ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Five year survival; Heart failure; HSP70; HSPA1A; Inflammation; Prognostic marker

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; CREATININE; HEAT SHOCK PROTEIN 70;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; SURVIVAL RATE; SURVIVAL TIME; SURVIVOR; SYSTOLIC HEART FAILURE;

AGE FACTORS; AGED; BIOLOGICAL MARKERS; BODY MASS INDEX; CREATININE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; SEX FACTORS;

EID: 84885475457     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-013-0425-z     Document Type: Article

References (21)

1. Asea A (2007) Mechanisms of HSP72 release. J Biosci 32(3):579-584
2. Daugaard M, Rohde M, Jaattela M (2007) The heat shock protein 70 family: highly homologous proteins with overlapping and distinct functions. FEBS Lett 581(19):3702-3710. doi: 10.1016/j.febslet.2007.05.039
3. Deedwania PC, Carbajal E (2012) Evidence-based therapy for heart failure. Med Clin N Am 96(5):915-931. doi: 10.1016/j.mcna.2012.07.010
4. Dybdahl B, Slordahl SA, Waage A, Kierulf P, Espevik T, Sundan A (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart 91(3):299-304. doi: 10.1136/hrt.2003.028092
5. Forhecz Z, Gombos T, Borgulya G, Pozsonyi Z, Prohaszka Z, Janoskuti L (2009) Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. Am Heart J 158(4):659-666. doi: 10.1016/j.ahj.2009.07.024
6. Genth-Zotz S, Bolger AP, Kalra PR, von Haehling S, Doehner W, Coats AJ, Volk HD, Anker SD (2004) Heat shock protein 70 in patients with chronic heart failure: relation to disease severity and survival. Int J Cardiol 96(3):397-401. doi: 10.1016/j.ijcard.2003.08.008
7. Giannessi D, Colotti C, Maltinti M, Del Ry S, Prontera C, Turchi S, Labbate A, Neglia D (2007) Circulating heat shock proteins and inflammatory markers in patients with idiopathic left ventricular dysfunction: their relationships with myocardial and microvascular impairment. Cell Stress Chaperones 12(3):265-274
8. Gombos T, Forhecz Z, Pozsonyi Z, Janoskuti L, Prohaszka Z (2008) Interaction of serum 70-kDa heat shock protein levels and HspA1B (+1267) gene polymorphism with disease severity in patients with chronic heart failure. Cell Stress Chaperones 13(2):199-206. doi: 10.1007/s12192-007-0001-5
9. Hecker JG, McGarvey M (2011) Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair. Cell Stress Chaperones 16(2):119-131. doi: 10.1007/s12192-010-0224-8
10. Henderson B, Pockley AG (2010) Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation. J Leukoc Biol 88(3):445-462. doi: 10.1189/jlb.1209779
11. Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford EA, Cheetham ME, Chen B, Hightower LE (2009) Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones 14(1):105-111. doi: 10.1007/s12192-008-0068-7
12. Krepuska M, Szeberin Z, Sotonyi P, Sarkadi H, Fehervari M, Apor A, Rimely E, Prohaszka Z, Acsady G (2011) Serum level of soluble Hsp70 is associated with vascular calcification. Cell Stress Chaperones 16(3):257-265. doi: 10.1007/s12192-010-0237-3
13. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Kober L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Ronnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A, Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, Bonet LA, Avraamides P, Ben Lamin HA, Brignole M, Coca A, Cowburn P, Dargie H, Elliott P, Flachskampf FA, Guida GF, Hardman S, Iung B, Merkely B, Mueller C, Nanas JN, Nielsen OW, Orn S, Parissis JT, Ponikowski P (2012) ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 14(8):803-869. doi: 10.1093/eurjhf/hfs105
14. Meng X, Brown JM, Ao L, Banerjee A, Harken AH (1996) Norepinephrine induces cardiac heat shock protein 70 and delayed cardioprotection in the rat through alpha 1 adrenoceptors. Cardiovasc Res 32(2):374-383
15. Moalic JM, Bauters C, Himbert D, Bercovici J, Mouas C, Guicheney P, Baudoin-Legros M, Rappaport L, Emanoil-Ravier R, Mezger V et al (1989) Phenylephrine, vasopressin and angiotensin II as determinants of proto-oncogene and heat-shock protein gene expression in adult rat heart and aorta. J Hypertens 7(3):195-201
16. Mosterd A, Hoes AW (2007) Clinical epidemiology of heart failure. Heart 93(9):1137-1146. doi: 10.1136/hrt.2003.025270
17. Pockley AG, Shepherd J, Corton JM (1998) Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals. Immunol Investig 27(6):367-377
18. Pugh PJ, Jones RD, Jones TH, Channer KS (2002) Heart failure as an inflammatory condition: potential role for androgens as immune modulators. Eur J Heart Fail 4(6):673-680
19. Satoh M, Shimoda Y, Akatsu T, Ishikawa Y, Minami Y, Nakamura M (2006) Elevated circulating levels of heat shock protein 70 are related to systemic inflammatory reaction through monocyte Toll signal in patients with heart failure after acute myocardial infarction. Eur J Heart Fail 8(8):810-815. doi: 10.1016/j.ejheart.2006.03.004
20. Wei YJ, Huang YX, Shen Y, Cui CJ, Zhang XL, Zhang H, Hu SS (2009) Proteomic analysis reveals significant elevation of heat shock protein 70 in patients with chronic heart failure due to arrhythmogenic right ventricular cardiomyopathy. Mol Cell Biochem 332(1-2):103-111. doi: 10.1007/s11010-009-0179- 1
21. Zhang X, Xu Z, Zhou L, Chen Y, He M, Cheng L, Hu FB, Tanguay RM, Wu T (2010) Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome. Cell Stress Chaperones 15(5):675-686. doi: 10.1007/s12192-010-0180-3