Circulating heat shock proteins and inflammatory markers in patients with idiopathic left ventricular dysfunction: Their relationships with myocardial and microvascular impairment

Cell Stress and Chaperones

Volumn 12, Issue 3, 2007, Pages 265-274

  Giannessi, Daniela ^a   Colotti, Chiara ^b   Maltinti, Maristella ^a   Del Ry, Silvia ^a   Prontera, Concetta ^a   Turchi, Stefano ^a   L'Abbate, Antonio ^b   Neglia, Danilo ^a  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; DIPYRIDAMOLE; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 60 ANTIBODY; HEAT SHOCK PROTEIN 72; INTERLEUKIN 6; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; AUTACOID; AUTOANTIBODY; CHAPERONIN; IL6 PROTEIN, HUMAN;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DISEASE SEVERITY; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE BLOOD FLOW; HUMAN; IDIOPATHIC DISEASE; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; MYOCARDIAL DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; BLOOD; COMPARATIVE STUDY; CORONARY ARTERY BLOOD FLOW; FORWARD HEART FAILURE; HEART CONTRACTION; HOSPITALIZATION; IMMUNOLOGY; METABOLISM; MICROCIRCULATION; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; AGED; AUTOANTIBODIES; C-REACTIVE PROTEIN; CARDIAC OUTPUT, LOW; CHAPERONIN 60; CORONARY CIRCULATION; FEMALE; HSP72 HEAT-SHOCK PROTEINS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MALE; MICROCIRCULATION; MIDDLE AGED; MYOCARDIAL CONTRACTION; NATRIURETIC PEPTIDE, BRAIN; SEVERITY OF ILLNESS INDEX; VENTRICULAR DYSFUNCTION, LEFT;

EID: 35348854947     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1379/CSC-272.1     Document Type: Article

References (31)

1. Asea A, Kraeft SK, Kurt-Jones EA, Stevenson MA, Chen LB, Finberg RW, Koo GC, Calderwood SK. 2000. Hsp70 stimulates cytokine production through a CD-14-dependent pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 6: 435-442.
2. Biasucci LM, Liuzzo G, Ciervo A, et al. 2003. Antibody response to chlamydial heat shock protein 60 is strongly associated with acute coronary syndromes. Circulation 107: 3015-3017.
3. Campisi J, Leem TH, Fleshner M. 2003. Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system. Cell Stress Chaperones 8: 272-286.
4. Del Ry S, Clerico A, Giannessi D, et al. 2000. Measurement of brain natriuretic peptide in plasma samples and cardiac tissue extracts by means of an immunoradiometric assay method. Scand J Clin Lab Invest 60: 81-90.
5. Depré C, Kim SJ, John AS, et al. 2004. Program of cell survival underlying human and experimental hibernating myocardium. Circ Res 95: 433-440.
6. Dybdahl B, Slordahl SA, Waage A, Kierulf P, Espevik T, Sundan A. 2005. Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart 91: 299-304.
7. Fallavollita JA, Jacob S, Young RF, Canty JM Jr. 1999. Regional alterations in SR Ca2+-ATPase, phospholamban, and Hsp70 expression in chronic hibernating myocardium. Am J Physiol Heart Circ Physiol 277: H1418-1428.
8. Genth-Zotz S, Bolger AP, Kalra PR, von Haehling S, Doehner W, Coats AJS, Volk HD, Anker SD. 2004. Heat shock protein 70 in patients with chronic heart failure: relation to disease severity and survival. Int J Cardiol 96: 397-401.
9. Hartl F. 1996. Molecular chaperones in cellular protein folding. Nature 381: 571-579.
10. Hightower LE. 1991. Heat shock, stress proteins, chaperones, and proteotoxicity. Cell 166: 191-197.
11. Kanwar RK, Kanwar JR, Wang D, Ormrod DJ, Krissansen GW. 2001. Temporal expression of heat shock proteins 60 and 70 at lesionprone sites during atherogenesis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 21: 1991-1997.
12. Knowlton AA, Brecher P, Apstein CS. 1991a. Rapid expression of heat shock proteins in the rabbit after brief cardiac ischemia. J Clin Invest 87: 139-147.
13. Knowlton AA, Eberli FR, Brecher P, Romo GM, Owen A, Apstein CS. 1991b. A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart. J Clin Invest 88: 2018-2025.
14. Knowlton AA, Kapadia S, Torre-Amione G, Durand JB, Bies R, Young J, Mann DL. 1998. Differential expression of heat shock proteins in normal and failing human hearts. J Mol Cell Cardiol 30: 811-818.
15. Kuhl U, Pauschinger M, Seeberg B, Lassner D, Noutsias M, Poller W, Pauschinger M. 2005. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation 112: 1965-1970.
16. Lang RM, Bierig M, Devereux RB, et al. 2005. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18: 1440-1463.
17. Latif N, Taylor PM, Khan MA, Yacoub MH, Dunn MJ. 1999. The expression of heat shock protein 60 in patients with dilated cardiomyopathy. Basic Res Cardiol 94: 112-119.
18. Mandal K, Jahangiri M, Xu Q. 2004. Autoimmunity to heat shock proteins in atherosclerosis. Autoimmunity Reviews 3: 31-37.
19. Martin JL, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann WH. 1997. Small heat shock proteins and protection against ischemic injury in cardiac myocytes. Circulation 96: 4343-4348.
20. Mestril R, Chi S, Sayen R, O'Reilly K, Dillman WH. 1994. Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against stimulated ischemia-induced injury. J Clin Invest 93: 759-767.
21. Morimoto RI. 1993. Cells in stress: transcriptional activation of heat shock genes. Science 259: 1409-1410.
22. Neglia D, Michelassi C, Trivieri MG, et al. 2002. Prognostic role of myocardial blood flow impairment in idiopathic left ventricular dysfunction. Circulation 105: 186-193.
23. Neglia D, Parodi O, Gallopin M, et al. 1995. Myocardial blood flow response to pacing tachycardia and to dipyridamole infusion in patients with dilated cardiomyopathy without overt heart failure. Circulation 92: 796-804.
24. Neglia D, Sambuceti G, Iozzo P, L'Abbate A, Strauss HW. 2002. Myocardial metabolic and receptor imaging in idiopathic dilated cardiomyopathy. Eur J Nucl Med Mol Imaging 29: 1403-1413.
25. Pilo A, Zucchelli GC, Malvano R, Masini S. 1982. Main features of computer algorithms for RIA data reduction. Comparison of same different approaches for the interpolation of dose-response curve. J Nucl Med All Sci 26: 235-248.
26. Portig I, Pankuweit S, Maisch B. 1997. Antibodies against stress proteins in sera of patients with dilated cardiomyopathy. J Mol Cell Cardiol 29: 2245-2251.
27. Sampietro T, Neglia D, Bionda A, et al. 2005. Inflammatory markers and serum lipids in idiopathic dilated cardiomyopathy. Am J Cardiol 96: 1718-1720.
28. Srivastava P. 2002. Roles of heat shock proteins in innate and adaptative immunity. Nature Rev Immunol 2: 185-194.
29. Valen G, Hansson GK, Dumitrescu A, Vaage J. 2000. Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factor NF-kb and AP-1. Cardiovasc Res 47: 49-56.
30. Van den Heuvel AF, Van Veldhuisen DJ, Van der Wall EE, Blanksma PK, Siebelink HM, Vaalburg WM, van Gilst WH, Crijns HJ. 2000. Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 35: 19-28.
31. Xu Q. 2002. Role of heat shock proteins in atherosclerosis. Arterioscler Thromb Vasc Biol 22: 1547-1559.