Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior

Developmental Psychobiology

Volumn 55, Issue 7, 2013, Pages 673-683

  Bromer, Cailey ^a   Marsit, Carmen J ^b,c   Armstrong, David A ^c   Padbury, James F ^b,d   Lester, Barry ^a,b,d  

^a WOMEN AND INFANTS HOSPITAL   (United States)

^b Women Infants' Hosp of Rhode Isl   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d BROWN UNIVERSITY   (United States)

Author keywords

Attention; Epigenetic; Glucocorticoid receptor; Human; Neurodevelopment; Placenta; Quality of movement

Indexed keywords

GLUCOCORTICOID RECEPTOR; NR3C1 PROTEIN, HUMAN;

ADULT; ARTICLE; ATTENTION; CHILD BEHAVIOR; DNA METHYLATION; EPIGENETIC; FEMALE; GENETIC EPIGENESIS; GENETICS; GENOTYPE; HUMAN; MALE; METABOLISM; MOVEMENT (PHYSIOLOGY); NERVE CELL DIFFERENTIATION; NEWBORN; PHYSIOLOGY; PLACENTA; PREGNANCY; PROMOTER REGION; QUALITY OF MOVEMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ATTENTION; EPIGENETIC; GLUCOCORTICOID RECEPTOR; HUMAN; NEURODEVELOPMENT; PLACENTA; QUALITY OF MOVEMENT;

ADULT; ATTENTION; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENOTYPE; HUMANS; INFANT BEHAVIOR; INFANT, NEWBORN; MALE; MOVEMENT; PLACENTA; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID;

EID: 84885475330     PISSN: 00121630     EISSN: 10982302     Source Type: Journal    
DOI: 10.1002/dev.21061     Document Type: Article

References (30)

1. Banister, C. E., Koestler, D. C., Maccani, M. A., Padbury, J. F., Houseman, E. A., & Marsit, C. J. (2011). Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas. [Research Support, N.I.H., Extramural]. Epigenetics: Official Journal of the DNA Methylation Society, 6(7), 920-927. doi: 10.4161/epi.6.7.16079
2. Bouma, E. M., Riese, H., Nolte, I. M., Oosterom, E., Verhulst, F. C., Ormel, J., & Oldehinkel, A. J. (2011). No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: The TRAILS Study. [Research Support, Non-U.S. Gov't]. Behavior Genetics, 41(2), 253-261. doi: 10.1007/s10519-010-9385-6
3. Champagne, F. A. (2010). Epigenetic perspectives on development: Evolving insights on the origins of variation. Developmental Psychobiology, 52(4), e1-e3. doi: 10.1002/dev.20443
4. Derijk, R. H. (2009). Single nucleotide polymorphisms related to HPA axis reactivity. [Research Support, Non-U.S. Gov't Review]. Neuroimmunomodulation, 16(5), 340-352. doi: 10.1159/000216192
5. Dolinoy, D. C., Das, R., Weidman, J. R., & Jirtle, R. L. (2007). Metastable epialleles, imprinting, and the fetal origins of adult diseases. [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Review]. Pediatric Research, 61(5 Pt 2), 30R-37R. doi: 10.1203/pdr.0b013e31804575f7
6. Ellman, L. M., Schetter, C. D., Hobel, C. J., Chicz-Demet, A., Glynn, L. M., & Sandman, C. A. (2008). Timing of fetal exposure to stress hormones: Effects on newborn physical and neuromuscular maturation. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]. Developmental Psychobiology, 50(3), 232-241. doi: 10.1002/dev.20293
7. Fenton, T. R. (2003). A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format. BMC Pediatrics, 3, 13. doi: 10.1186/1471-2431-3-13
8. Filiberto, A. C., Maccani, M. A., Koestler, D., Wilhelm-Benartzi, C., Avissar-Whiting, M., Banister, C. E., Marsit, C. J. (2011). Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta. [Research Support, N.I.H., Extramural]. Epigenetics: Official Journal of the DNA Methylation Society, 6(5), 566-572.
9. Hanson, M. A., & Gluckman, P. D. (2008). Developmental origins of health and disease: New insights. [Research Support, Non-U.S. Gov't Review]. Basic & Clinical Pharmacology & Toxicology, 102(2), 90-93. doi: 10.1111/j.1742-7843.2007.00186.x
10. Lester, B. M., & Padbury, J. F. (2009). Third pathophysiology of prenatal cocaine exposure. Developmental Neuroscience, 31(1-2), 23-35. doi: 000207491[pii]10.1159/000207491
11. Lester, B., & Tronick, E. (2004). The Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics, 113(Suppl. 3 Pt 2), 631-695.
12. Liu, J. H. (2009). Endocrinology of pregnancy. In C. A. Resnik (Ed.), Maternal-fetal medicine, principles and practice (6th ed., pp. 111-124). Philadelphia: Saunders Elsevier.
13. Liu, J., Bann, C., Lester, B., Tronick, E., Das, A., Lagasse, L., . Bada, H. (2010). Neonatal neurobehavior predicts medical and behavioral outcome. Pediatrics, 125(1), e90-e98. doi: peds.2009-0204[pii]10.1542/peds.2009-0204
14. Maccani, M. A., & Marsit, C. J. (2009). Epigenetics in the placenta. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review]. American Journal of Reproductive Immunology, 62(2), 78-89. doi: 10.1111/j.1600-0897.2009.00716.x
15. Marsit, C. J., Lambertini, L., Maccani, M. A., Koestler, D. C., Houseman, E. A., Padbury, J. F., . Chen, J. (2011). Placenta-imprinted gene expression association of infant neurobehavior. The Journal of Pediatrics, 160(5), 854-860. doi: 10.1016/j.jpeds.2011.10.028
16. Marsit, C. J., Maccani, M. A., Padbury, J. F., & Lester, B. M. (2012). Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome. PLoS ONE, 7(3), e33794. doi: 10.1371/journal.pone.0033794
17. Mathers, J. C., & McKay, J. A. (2009). Epigenetics-Potential contribution to fetal programming. [Research Support, Non-U.S. Gov't Review]. Advances in Experimental Medicine and Biology, 646, 119-123. doi: 10.1007/978-1-4020-9173-5_13
18. McGowan, P. O., Sasaki, A., D'Alessio, A. C., Dymov, S., Labonte, B., Szyf, M., . Meaney, M. J. (2009). Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. [Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]. Nature Neuroscience, 12(3), 342-348. doi: 10.1038/nn.2270
19. McMillen, I. C., & Robinson, J. S. (2005). Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiological Reviews, 85(2), 571-633. doi: 85/2/571[pii]10.1152/physrev.00053.2003
20. Oberlander, T. F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., & Devlin, A. M. (2008). Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics, 3(2), 97-106. doi: 6034[pii]
21. Ponder, K. L., Salisbury, A., McGonnigal, B., Laliberte, A., Lester, B., & Padbury, J. F. (2011). Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: Implications for fetal programming. Developmental Psychobiology, 53(7), 711-723. doi: 10.1002/dev.20549
22. Robins, J. C., Marsit, C. J., Padbury, J. F., & Sharma, S. S. (2011). Endocrine disruptors, environmental oxygen, epigenetics and pregnancy. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review]. Frontiers in Bioscience, 3, 690-700.
23. Roth, T. L., & Sweatt, J. D. (2011). Annual research review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review]. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 52(4), 398-408. doi: 10.1111/j.1469-7610.2010.02282.x
24. Sarkar, S., Tsai, S. W., Nguyen, T. T., Plevyak, M., Padbury, J. F., & Rubin, L. P. (2001). Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by catecholamines via alpha-adrenergic signaling. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 281(6), R1966-R1974.
25. Seckl, J. R., & Meaney, M. J. (2006). Glucocorticoid "programming" and PTSD risk. Annals of the New York Academy of Sciences, 1071, 351-378.
26. Slone-Wilcoxon, J., & Redei, E. E. (2004). Maternal-fetal glucocorticoid milieu programs hypothalamic-pituitary-thyroid function of adult offspring. Endocrinology, 145(9), 4068-4072. doi: 10.1210/en.2004-0473en.2004-0473[pii]
27. Tremblay, R. E. (2010). Developmental origins of disruptive behaviour problems: The 'original sin' hypothesis, epigenetics and their consequences for prevention. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 51(4), 341-367. doi: 10.1111/j.1469-7610.2010.02211.x
28. Van den Bergh, B. R. (2011). Developmental programming of early brain and behaviour development and mental health: A conceptual framework. Developmental Medicine and Child Neurology, 4(53 Suppl.), 19-23. doi: 10.1111/j.1469-8749.2011.04057.x
29. Weaver, I. C., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., . Meaney, M. J. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7(8), 847-854. doi: 10.1038/nn1276nn1276[pii]
30. Welberg, L. A., & Seckl, J. R. (2001). Prenatal stress, glucocorticoids and the programming of the brain. Journal of Neuroendocrinology, 13(2), 113-128. doi: jne601[pii]