Characterization of Lung Cancer by Amide Proton Transfer (APT) Imaging: An In-Vivo Study in an Orthotopic Mouse Model

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Togao, Osamu ^a   Kessinger, Chase W ^a   Huang, Gang ^a   Soesbe, Todd C ^a   Sagiyama, Koji ^a   Dimitrov, Ivan ^a   Sherry, A Dean ^a   Gao, Jinming ^a   Takahashi, Masaya ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; PROTON;

AMIDE PROTON TRANSFER IMAGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER CLASSIFICATION; CANCER GRADING; CANCER SURGERY; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FEASIBILITY STUDY; FEMALE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMAGE QUALITY; IN VIVO STUDY; INVASIVE PROCEDURE; LUNG CANCER; MOUSE; NEEDLE BIOPSY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; TREATMENT INDICATION; TUMOR DIFFERENTIATION; TUMOR XENOGRAFT;

AMIDES; ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MOLECULAR IMAGING; PROTONS; RESPIRATORY-GATED IMAGING TECHNIQUES; WATER;

EID: 84885440227     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077019     Document Type: Article

References (41)

1. Pastorino U, (2010) Lung cancer screening. Br J Cancer 102: 1681-1686.
2. Hansell DM (1999) High-resolution computed tomography in the evaluation of fibrosing alveolitis. Clin Chest Med 20: 739-760, viii.
3. Lindell RM, Hartman TE, Swensen SJ, Jett JR, Midthun DE, et al. (2009) 5-year lung cancer screening experience: growth curves of 18 lung cancers compared to histologic type, CT attenuation, stage, survival, and size. Chest 136: 1586-1595.
4. Swensen SJ, Jett JR, Hartman TE, Midthun DE, Sloan JA, et al. (2003) Lung cancer screening with CT: Mayo Clinic experience. Radiology 226: 756-761.
5. Revel MP, Bissery A, Bienvenu M, Aycard L, Lefort C, et al. (2004) Are two-dimensional CT measurements of small noncalcified pulmonary nodules reliable? Radiology 231: 453-458.
6. Kubo T, Lin PJ, Stiller W, Takahashi M, Kauczor HU, et al. (2008) Radiation dose reduction in chest CT: a review. AJR Am J Roentgenol 190: 335-343.
7. Smith-Bindman R, (2010) Is computed tomography safe? N Engl J Med 363: 1-4.
8. Lindell RM, Hartman TE, Swensen SJ, Jett JR, Midthun DE, et al. (2005) Lung cancer screening experience: a retrospective review of PET in 22 non-small cell lung carcinomas detected on screening chest CT in a high-risk population. AJR Am J Roentgenol 185: 126-131.
9. Henschke CI, McCauley DI, Yankelevitz DF, Naidich DP, McGuinness G, et al. (1999) Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet 354: 99-105.
10. Diederich S, Wormanns D, Lenzen H, Semik M, Thomas M, et al. (2000) Screening for asymptomatic early bronchogenic carcinoma with low dose CT of the chest. Cancer 89: 2483-2484.
11. Matsuoka S, Hunsaker AR, Gill RR, Jacobson FL, Ohno Y, et al. (2008) Functional MR imaging of the lung. Magn Reson Imaging Clin N Am 16: 275-289, ix.
12. van Zijl PC, Jones CK, Ren J, Malloy CR, Sherry AD, (2007) MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST). Proc Natl Acad Sci U S A 104: 4359-4364.
13. Mani T, Tircso G, Togao O, Zhao P, Soesbe TC, et al. (2009) Modulation of water exchange in Eu(III) DOTA-tetraamide complexes: considerations for in vivo imaging of PARACEST agents. Contrast Media Mol Imaging 4: 183-191.
14. Ren J, Trokowski R, Zhang S, Malloy CR, Sherry AD, (2008) Imaging the tissue distribution of glucose in livers using a PARACEST sensor. Magn Reson Med 60: 1047-1055.
15. Zhou J, Payen JF, Wilson DA, Traystman RJ, van Zijl PC, (2003) Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat Med 9: 1085-1090.
16. Zhou J, Lal B, Wilson DA, Laterra J, van Zijl PC, (2003) Amide proton transfer (APT) contrast for imaging of brain tumors. Magn Reson Med 50: 1120-1126.
17. Salhotra A, Lal B, Laterra J, Sun PZ, van Zijl PC, et al. (2008) Amide proton transfer imaging of 9L gliosarcoma and human glioblastoma xenografts. NMR Biomed 21: 489-497.
18. Zhou J, Blakeley JO, Hua J, Kim M, Laterra J, et al. (2008) Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging. Magn Reson Med 60: 842-849.
19. Howe FA, Barton SJ, Cudlip SA, Stubbs M, Saunders DE, et al. (2003) Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy. Magn Reson Med 49: 223-232.
20. Kubo S, Levantini E, Kobayashi S, Kocher O, Halmos B, et al. (2006) Three-dimensional magnetic resonance microscopy of pulmonary solitary tumors in transgenic mice. Magn Reson Med 56: 698-703.
21. Takahashi M, Kubo S, Kiryu S, Gee J, Hatabu H, (2007) MR microscopy of the lung in small rodents. Eur J Radiol 64: 367-374.
22. Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, et al. (2010) Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy. Cancer Res 70: 3896-3904.
23. Madero-Visbal RA, Colon JF, Hernandez IC, Limaye A, Smith J, et al. (2010) Bioluminescence imaging correlates with tumor progression in an orthotopic mouse model of lung cancer. Surg Oncol.
24. Takahashi M, Togao O, Obara M, van Cauteren M, Ohno Y, et al. (2010) Ultra-short echo time (UTE) MR imaging of the lung: comparison between normal and emphysematous lungs in mutant mice. J Magn Reson Imaging 32: 326-333.
25. Togao O, Tsuji R, Ohno Y, Dimitrov I, Takahashi M, (2010) Ultrashort echo time (UTE) MRI of the lung: Assessment of tissue density in the lung parenchyma. Magn Reson Med 64: 1491-1498.
26. Jones CK, Schlosser MJ, van Zijl PC, Pomper MG, Golay X, et al. (2006) Amide proton transfer imaging of human brain tumors at 3T. Magn Reson Med 56: 585-592.
27. Imbalzano KM, Tatarkova I, Imbalzano AN, Nickerson JA, (2009) Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture. Cancer Cell Int 9: 7.
28. Kiryu S, Loring SH, Mori Y, Rofsky NM, Hatabu H, et al. (2006) Quantitative analysis of the velocity and synchronicity of diaphragmatic motion: dynamic MRI in different postures. Magn Reson Imaging 24: 1325-1332.
29. Kino A, Takahashi M, Ashiku SK, Decamp MM, Lenkinski RE, et al. (2007) Optimal breathing protocol for dynamic contrast-enhanced MRI of solitary pulmonary nodules at 3T. Eur J Radiol 64: 397-400.
30. Pekar J, Jezzard P, Roberts DA, Leigh JS Jr, Frank JA, et al. (1996) Perfusion imaging with compensation for asymmetric magnetization transfer effects. Magn Reson Med 35: 70-79.
31. van Zijl PC, Zhou J, Mori N, Payen JF, Wilson D, et al. (2003) Mechanism of magnetization transfer during on-resonance water saturation. A new approach to detect mobile proteins, peptides, and lipids. Magn Reson Med 49: 440-449.
32. Hua J, Jones CK, Blakeley J, Smith SA, van Zijl PC, et al. (2007) Quantitative description of the asymmetry in magnetization transfer effects around the water resonance in the human brain. Magn Reson Med 58: 786-793.
33. Szentirmai O, Baker CH, Lin N, Szucs S, Takahashi M, et al. (2006) Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect. Neurosurgery 58: 365-372; discussion 365-372.
34. Kangasniemi K, Sagiyama K, Gao B, Huang J, Minnna M, et al. (2012) Characterization of lung tumor cell lines by amide proton transfer (APT) imaging in in-vitro system. Proceeding of the 20th Annual Meeting and Exhibition, International Society for Magnetic Resonance in Medicine. 2012; Melbourne, Austraria.
35. Dimitrov I, Takahashi M, Sagiyama K, Sherry AD, Keupp J (2012) In-vivo human kidney pH mapping at 3T using time-interleaved parallel RF transmission CEST. Proceeding of the 20th Annual Meeting and Exhibition, International Society for Magnetic Resonance in Medicine. 2012; Melbourne, Austraria.
36. Varma G, Lenkinski RE, Vinogradov E, (2012) Keyhole chemical exchange saturation transfer. Magn Reson Med 68: 1228-1233.
37. Keall PJ, Mageras GS, Balter JM, Emery RS, Forster KM, et al. (2006) The management of respiratory motion in radiation oncology report of AAPM Task Group 76. Med Phys 33: 3874-3900.
38. Zhao X, Wen Z, Zhang G, Huang F, Lu S, et al. (2012) Three-Dimensional Turbo-Spin-Echo Amide Proton Transfer MR Imaging at 3-Tesla and Its Application to High-Grade Human Brain Tumors. Mol Imaging Biol 15: 114-122.
39. Kim M, Gillen J, Landman BA, Zhou J, van Zijl PC, (2009) Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments. Magn Reson Med 61: 1441-1450.
40. Scheidegger R, Vinogradov E, Alsop DC, (2011) Amide proton transfer imaging with improved robustness to magnetic field inhomogeneity and magnetization transfer asymmetry using saturation with frequency alternating RF irradiation. Magn Reson Med 66: 1275-1285.
41. Soesbe TC, Togao O, Takahashi M, Sherry AD, (2012) SWIFT-CEST: A new MRI method to overcome T(2) shortening caused by PARACEST contrast agents. Magn Reson Med 68: 816-821.