More than one ring to bind them all: Recent insights into the structure of the axon

Developmental Neurobiology

Volumn 73, Issue 11, 2013, Pages 799-805

  Gallo, Gianluca ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adducin; Branching; Cortactin; Dynamin; Filopodia; Filopodium; Guidance; Microtubules; Septin; Spectrin; Sprouting

Indexed keywords

ACTIN; CORTACTIN; DYNAMIN; DYNAMIN I; DYNAMIN II; SPECTRIN;

ACTIN FILAMENT; ARTICLE; BRAIN CORTEX; CELL MATURATION; CELL MEMBRANE; CELL STRUCTURE; CYTOSKELETON; DENDRITE; FILOPODIUM; GROWTH CONE; HIPPOCAMPAL NEURONAL CULTURE; HUMAN; MICROTUBULE; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ULTRASTRUCTURE;

ADDUCIN; BRANCHING; CORTACTIN; DYNAMIN; FILOPODIA; FILOPODIUM; GUIDANCE; MICROTUBULES; SEPTIN; SPECTRIN; SPROUTING;

ACTIN CYTOSKELETON; ANIMALS; AXONS; GROWTH CONES; HUMANS;

EID: 84885434025     PISSN: 19328451     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/dneu.22100     Document Type: Article

References (27)

1. Brown JA, Bridgman PC. 2009. Disruption of the cytoskeleton during Semaphorin 3A induced growth cone collapse correlates with differences in actin organization and associated binding proteins. Dev Neurobiol 69:633-646.
2. Burnette DT, Ji L, Schaefer AW, Medeiros NA, Danuser G, Forscher P. 2008. Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck. Dev Cell 15:163-169.
3. Dent EW, Gertler FB. 2003. Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 40:209-227.
4. Faty M, Fink M, Barral Y. 2002. Septins: A ring to part mother and daughter. Curr Genet 413:123-131.
5. Flynn KC, Pak CW, Shaw AE, Bradke F, Bamburg JR. 2009. Growth cone-like waves transport actin and promote axonogenesis and neurite branching. Dev Neurobiol 69:761-779.
6. Gallo G. 2006. RhoA-kinase coordinates F-actin organization and myosin II activity during semaphorin-3A-induced axon retraction. J Cell Sci 119(Pt 16):3413-3423.
7. Gallo G. 2011. The cytoskeletal and signaling mechanisms of axon collateral branching. Dev Neurobiol 71:201-220.
8. Gallo G. 2013. Mechanisms underlying the initiation and dynamics of neuronal filopodia: from neurite formation to synaptogenesis. Int Rev Cell Mol Biol 301:95-156.
9. Hammarlund M, Jorgensen EM, Bastiani MJ. 2007. Axons break in animals lacking beta-spectrin. J Cell Biol 176:269-275.
10. Hu J, Bai X, Bowen JR, Dolat L, Korobova F, Yu W, Baas PW, et al. 2012. Septin-driven coordination of actin and microtubule remodeling regulates the collateral branching of axons. Curr Biol 22:1109-1115.
11. Ketschek A, Gallo G. 2010. Nerve growth factor induces axonal filopodia through localized microdomains of phosphoinositide 3-kinase activity that drive the formation of cytoskeletal precursors to filopodia. J Neurosci 30:12185-12197.
12. Kirchhausen T, Macia E, Pelish HE. 2008. Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis. Methods Enzymol 438:77-93.
13. Korobova F, Svitkina T. 2010. Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis. Mol Biol Cell 21:165-176.
14. Loudon RP, Silver LD, Yee HF Jr, Gallo G. (2006) RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor. J Neurobiol 66:847-867.
15. Mingorance-Le Meur A, O'Connor TP. 2009. Neurite consolidation is an active process requiring constant repression of protrusive activity. EMBO J 28:248-260.
16. Pollard TD. 2010. Mechanics of cytokinesis in eukaryotes. Curr Opin Cell Biol 22:50-56.
17. Pathak D, Sepp KJ, Hollenbeck PJ. 2010. Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria. J Neurosci 30:8984-8992.
18. Poliak S, Peles E. 2003. The local differentiation of myelinated axons at nodes of Ranvier. Nat Rev Neurosci 4:968-980.
19. Rasband MN. 2013. Cytoskeleton: axons earn their stripes. Curr Biol 23:R197-R198.
20. Ren G, Crampton MS, Yap AS. 2009. Cortactin: Coordinating adhesion and the actin cytoskeleton at cellular protrusions. Cell Motil Cytoskeleton 66:865-873.
21. Ruthel G, Banker G. 1988. Actin-dependent anterograde movement of growth-cone-like structures along growing hippocampal axons: A novel form of axonal transport? Cell Motil Cytoskeleton 40:160-173.
22. Steketee MB, Tosney KW. 2002. Three functionally distinct adhesions in filopodia: Shaft adhesions control lamellar extension. J Neurosci 22:8071-8083.
23. Spillane M, Ketschek A, Donnelly CJ, Pacheco A, Twiss JL, Gallo G. 2012. Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex. J Neurosci 32:17671-17689.
24. Spillane M, Ketschek A, Jones SL, Korobova F, Marsick B, Lanier L, Svitkina T, et al. 2011. The actin nucleating Arp2/3 complex contributes to the formation of axonal filopodia and branches through the regulation of actin patch precursors to filopodia. Dev Neurobiol 71:747-758.
25. Xu K, Zhong G, Zhuang X. 2013. Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science 339:452-456.
26. Yamada H, Abe T, Satoh A, Okazaki N, Tago S, Kobayashi K, Yoshida Y, et al. 2013. Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia. J Neurosci 33:4514-4526.
27. Zhang XF, Schaefer AW, Burnette DT, Schoonderwoert VT, Forscher P. 2003. Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow. Neuron 40:931-944.