Higher mean arterial pressure with or without vasoactive agents is associated with increased survival and better neurological outcomes in comatose survivors of cardiac arrest

Intensive Care Medicine

Volumn 39, Issue 11, 2013, Pages 1981-1988

  Beylin, Marie E ^a,b   Perman, Sarah M ^a,c   Abella, Benjamin S ^a   Leary, Marion ^a   Shofer, Frances S ^a   Grossestreuer, Anne V ^a   Gaieski, David F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SAN FRANCISCO GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Blood pressure; Cardiac arrest; Goal directed therapy; Hemodynamic optimization; Post cardiac arrest care; Therapeutic hypothermia

Indexed keywords

ADRENALIN; DOBUTAMINE; DOPAMINE; ESMOLOL; GLYCERYL TRINITRATE; HYPERTENSIVE AGENT; INOTROPIC AGENT; METOPROLOL TARTRATE; MILRINONE; NITROPRUSSIDE SODIUM; NORADRENALIN; PHENYLEPHRINE; VASOACTIVE AGENT; VASODILATOR AGENT; VASOPRESSIN;

ADULT; ALGORITHM; ARTICLE; BODY TEMPERATURE; BRAIN PERFUSION; CARDIOVASCULAR DISEASE; CENTRAL VENOUS PRESSURE; CEREBROVASCULAR ACCIDENT; CLINICAL PRACTICE; CLINICAL PROTOCOL; COMA; COMORBIDITY; COOLING; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE SEVERITY; DRUG DOSE TITRATION; FEMALE; FLUID THERAPY; HEART ARREST; HEART CATHETERIZATION; HEART OUTPUT; HEMODYNAMIC MONITORING; HEMODYNAMIC PARAMETERS; HUMAN; HYPERLIPIDEMIA; INTENSIVE CARE UNIT; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; OUT OF HOSPITAL CARDIAC ARREST; OUTCOMES RESEARCH; OXYGEN SATURATION; PATIENT MONITORING; PERCUTANEOUS CORONARY INTERVENTION; POST CARDIAC ARREST SYNDROME; PRACTICE GUIDELINE; SEPSIS; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; WARMING;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; ARTERIAL PRESSURE; COMA; COMORBIDITY; FEMALE; HEART ARREST; HEMODYNAMICS; HUMANS; HYPOTENSION; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; PENNSYLVANIA; REGISTRIES; RETROSPECTIVE STUDIES; SURVIVORS;

EID: 84885424050     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-013-3075-9     Document Type: Article

References (23)

1. Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, Smith K (2002) Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 346(8):557-563
2. Hypothermia after Cardiac Arrest Study Group (2002) Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 346:549-556
3. Peberdy MA, Callaway CW, Neumar RW, Geocadin RG, Zimmerman JL, Donnino M, Gabrielli A, Silvers SM, Zaritsky AL, Merchant R, Vanden Hoek TL, Kronick SL (2010) Part 9: Post-cardiac arrest care: 2010 American heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 122:S768-S786
4. Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Böttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT Jr, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T (2008) Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation 118:2452-2483
5. Adrie C, Laurent I, Monchi M, Cariou A, Dhainaou JF, Spaulding C (2004) Post resuscitation disease after cardiac arrest: A sepsis-like syndrome? Curr Opin Crit Care 10:208-212
6. Adrie C, Adib-Conquy M, Laurent I, Monchi M, Vinsonneau C, Fitting C, Fraisse F, Dinh-Xuan AT, Carli P, Spaulding C, Dhainaut JF, Cavaillon JM (2002) Successful cardiopulmonary resuscitation after cardiac arrest as a sepsis-like syndrome. Circulation 106:562-568
7. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368-1377
8. Laver S, Farrow C, Turner D, Nolan J (2004) Mode of death after admission to an intensive care unit following cardiac arrest. Intensive Care Med 30:2126-2128
9. Nolan JP, Soar J (2008) Post resuscitation care-Time for a bundle?. Resuscitation 76:161-162
10. Laurent I, Monchi M, Chiche JD, Joly LM, Spaulding C, Bourgeois B, Cariou A, Rozenberg A, Carli P, Weber S, Dhainaut JF (2002) Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest. J Am Coll Cardiol 40:2110-2116
11. Jones AE, Shapiro NI, Kilgannon JH, Trzeciak S (2008) Goal-directed hemodynamic optimization in the post-cardiac arrest syndrome: A systematic review. Resuscitation 77:26-29
12. Gaieski DF, Neumar RW, Fuchs B, Abella BS, Kolansky D, Delfin G, Leary M, Goyal M (2012) Hemodynamic management strategies are not explicitly defined in the majority of therapeutic hypothermia implementation studies. Resuscitation 83:835-839
13. Gaieski DF, Band RA, Abella BS, Neumar RW, Fuchs BD, Kolansky DM, Merchant RM, Carr BG, Becker LB, Maguire C, Klair A, Hylton J, Goyal M (2009) Early goal-directed hemodynamic optimization combined with therapeutic hypothermia in comatose survivors of out-of-hospital cardiac arrest. Resuscitation 80:418-424
14. Sunde K, Pytte M, Jacobsen D, Mangschau A, Jensen LP, Smedsrud C, Draegni T, Steen PA (2007) Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest. Resuscitation 73:29-39
15. Zobel C, Adler C, Kranz A, Seck C, Pfister R, Hellmich M, Kochanek M, Reuter H (2012) Mild therapeutic hypothermia in cardiogenic shock syndrome. Crit Care Med 40:1715-1723
16. Schmidt-Schweda S, Ohler A, Post H, Pieske B (2013) Moderate hypothermia for severe cardiogenic shock (COOL Shock Study I & II). Resuscitation 84:319-325
17. Jacobshagen C, Pelster T, Pax A, Horn W, Schmidt-Schweda S, Unsöld BW, Seidler T, Wagner S, Hasenfuss G, Maier LS (2010) Effects of mild hypothermia on hemodynamics in cardiac arrest survivors and isolated failing human myocardium. Clin Res Cardiol 99:267-276
18. Rittenberger JC, Tisherman SA, Holm MB, Guyette FX, Callaway CW (2011) An early, novel illness severity score to predict outcome after cardiac arrest. Resuscitation 82:1399-1404
19. Trzeciak S, Jones AE, Kilgannon JH, Milcarek B, Hunter K, Shapiro NI, Hollenberg SM, Dellinger P, Parrillo JE (2009) Significance of arterial hypotension after resuscitation from cardiac arrest. Crit Care Med 37:2895-2903
20. Müllner M, Sterz F, Binder M, Hellwagner K, Meron G, Herkner H, Laggner AN (1996) Arterial blood pressure after human cardiac arrest and neurological recovery. Stroke 27:59-62
21. Safar P, Xiao F, Radovsky A, Tanigawa K, Ebmeyer U, Bircher N, Alexander H, Stezoski SW (1996) Improved cerebral resuscitation from cardiac arrest in dogs with mild hypothermia plus blood flow promotion. Stroke 27:105-113
22. Nolan JP (2013) What's new in the management of cardiac arrest? Intensive Care Med 39:1211-1213
23. Augusto J-F, Teboul J-L, Radermacher P, Asfar P (2011) Interpretation of blood pressure signal: Physiologic bases, clinical relevance, and objectives during shock states. Intensive Care Med 37:411-419