Association analysis of two candidate polymorphisms in the Tumour Necrosis Factor-α gene with osteoarthritis in a Chinese population

International Orthopaedics

Volumn 37, Issue 10, 2013, Pages 2061-2063

  Ji, Bin ^a   Shi, Jixiang ^a   Cheng, Xiangyu ^a   Zhou, Junjie ^a   Zhou, Qiang ^a   Cao, Chengfu ^a   Pang, Jinhui ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHINESE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPING TECHNIQUE; HUMAN; MAJOR CLINICAL STUDY; MOLECULAR PATHOLOGY; OSTEOARTHRITIS; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR NECROSIS FACTOR ALPHA GENE;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; OSTEOARTHRITIS; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885421785     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-013-1931-4     Document Type: Article

References (14)

1. Reynard LN, Loughlin J (2012) Genetics and epigenetics of osteoarthritis. Maturitas 71(3):200-204. doi: 10.1016/j.maturitas.2011.12.001
2. Hoff P, Buttgereit F, Burmester GR, Jakstadt M, Gaber T, Andreas K, Matziolis G, Perka C, Rohner E (2013) Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes. Int Orthop 37(1):145-151. doi: 10.1007/s00264-012-1724-1
3. Pelletier JP, Martel-Pelletier J, Abramson SB (2001) Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets. Arthritis Rheum 44(6):1237-1247. doi: 10.1002/1529-0131(200106)44: 6<1237::aid-art214>3.0.co;2-f
4. Janeway C, Travers P, Walport M, Capra J (1999) Immunobiology: the immune system in health and disease. Garland Publishers, New York
5. Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H (2011) Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 7(1):33-42. doi: 10.1038/nrrheum.2010.196
6. Munoz-Valle JF, Oregon-Romero E, Rangel-Villalobos H, Martinez-Bonilla GE, Castaneda-Saucedo E, Salgado-Goytia L, Leyva-Vazquez MA, Illades-Aguiar B, Alarcon-Romero LD, Espinoza-Rojo M, Parra-Rojas I (2012) High expression of TNF alpha is associated with -308 and -238 TNF alpha polymorphisms in knee osteoarthritis. Clin Exp Med. doi: 10.1007/s10238-012-0216-3
7. Kroeger KM, Carville KS, Abraham LJ (1997) The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 34(5):391-399
8. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW (1997) Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 94(7):3195-3199
9. Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld AE (1998) Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. Tissue Antigens 52(4):359-367
10. Han L, Song JH, Yoon JH, Park YG, Lee SW, Choi YJ, Nam SW, Lee JY, Park WS (2012) TNF-alpha and TNF-beta polymorphisms are associated with susceptibility to osteoarthritis in a Korean population. Korean J Pathol 46(1):30-37. doi: 10.4132/KoreanJPathol.2012.46.1.30
11. Sezgin M, Barlas IO, Ankarali HC, Altintas ZM, Turkmen E, Gokdogan T, Sahin G, Erdal ME (2008) Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population. Clin Exp Rheumatol 26(5):763-768
12. Sellam J, Berenbaum F (2010) The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol 6(11):625-635. doi: 10.1038/nrrheum.2010.159
13. Shi D, Zheng Q, Chen D, Zhu L, Qin A, Fan J, Liao J, Xu Z, Lin Z, Norman P, Xu J, Nakamura T, Dai K, Zheng M, Jiang Q (2010) Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis. Osteoarthr Cartil/OARS Osteoarthr Res Soc 18(11):1454-1457. doi: 10.1016/j.joca.2010.07.009
14. Nakajima M, Takahashi A, Kou I, Rodriguez-Fontenla C, Gomez-Reino JJ, Furuichi T, Dai J, Sudo A, Uchida A, Fukui N, Kubo M, Kamatani N, Tsunoda T, Malizos KN, Tsezou A, Gonzalez A, Nakamura Y, Ikegawa S (2010) New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. PLoS One 5(3):e9723. doi: 10.1371/journal.pone.0009723