Overnight Resting of PBMC Changes Functional Signatures of Antigen Specific T- Cell Responses: Impact for Immune Monitoring within Clinical Trials

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Kutscher, Sarah ^a,b,h   Dembek, Claudia J ^a,b,g   Deckert, Simone ^a,b   Russo, Carolina ^a   Körber, Nina ^a   Bogner, Johannes R ^c   Geisler, Fabian ^d   Umgelter, Andreas ^d   Neuenhahn, Michael ^b,e   Albrecht, Julia ^b,e   Cosma, Antonio ^f   Protzer, Ulrike ^a,b,g   Bauer, Tanja ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f DIF   (France)

^g German Center for Infection Research   (Germany)

^h IMMATICS BIOTECHNOLOGIES GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD40 LIGAND; CD45RA ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL VIABILITY; CLINICAL ARTICLE; CLINICAL TRIAL (TOPIC); COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; FEMALE; FLOW CYTOMETRY; FREEZE THAWING; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOREGULATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; SEROLOGY; T LYMPHOCYTE; VIRUS REPLICATION;

ADULT; AGED; ANTIGEN-PRESENTING CELLS; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CHEMOKINES; CLINICAL TRIALS AS TOPIC; CRYOPRESERVATION; EPITOPES; EPITOPES, T-LYMPHOCYTE; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTRACELLULAR SPACE; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MONITORING, IMMUNOLOGIC; STAINING AND LABELING; TIME FACTORS;

EID: 84885418048     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076215     Document Type: Article

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